Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Sonal Nagarkar-Jaiswal"'
Publikováno v:
Bio-Protocol, Vol 9, Iss 3 (2019)
Mosaic analysis in Drosophila, an important tool to assess cellular phenotypes of mutants in an otherwise heterozygous background, relies on mitosis. Hence, it cannot be used to inactivate gene function in mitotically inactive, terminally differentia
Externí odkaz:
https://doaj.org/article/977f9c9283e64401b59683b64fdafbda
Autor:
James Ashley, Violet Sorrentino, Meike Lobb-Rabe, Sonal Nagarkar-Jaiswal, Liming Tan, Shuwa Xu, Qi Xiao, Kai Zinn, Robert A Carrillo
Publikováno v:
eLife, Vol 8 (2019)
The Drosophila larval neuromuscular system provides an ideal context in which to study synaptic partner choice, because it contains a small number of pre- and postsynaptic cells connected in an invariant pattern. The discovery of interactions between
Externí odkaz:
https://doaj.org/article/6df7118dc7a14dcd9d8f2b74758845cb
Autor:
Lalanti Venkatasubramanian, Zhenhao Guo, Shuwa Xu, Liming Tan, Qi Xiao, Sonal Nagarkar-Jaiswal, Richard S Mann
Publikováno v:
eLife, Vol 8 (2019)
For animals to perform coordinated movements requires the precise organization of neural circuits controlling motor function. Motor neurons (MNs), key components of these circuits, project their axons from the central nervous system and form precise
Externí odkaz:
https://doaj.org/article/a04437481466484b8021625a8f8e3619
Publikováno v:
eLife, Vol 6 (2017)
Here, we describe a novel method based on intronic MiMIC insertions described in Nagarkar-Jaiswal et al. (2015) to perform conditional gene inactivation in Drosophila. Mosaic analysis in Drosophila cannot be easily performed in post-mitotic cells. We
Externí odkaz:
https://doaj.org/article/4a16979eb9374174a13a109dd687cfc5
Autor:
Samuel O Skinner, Heng Xu, Sonal Nagarkar-Jaiswal, Pablo R Freire, Thomas P Zwaka, Ido Golding
Publikováno v:
eLife, Vol 5 (2016)
Transcription is a highly stochastic process. To infer transcription kinetics for a gene-of-interest, researchers commonly compare the distribution of mRNA copy-number to the prediction of a theoretical model. However, the reliability of this procedu
Externí odkaz:
https://doaj.org/article/a50ec689bdd14cb0a8eaf4f0ea82da76
Autor:
Sonal Nagarkar-Jaiswal, Steven Z DeLuca, Pei-Tseng Lee, Wen-Wen Lin, Hongling Pan, Zhongyuan Zuo, Jiangxing Lv, Allan C Spradling, Hugo J Bellen
Publikováno v:
eLife, Vol 4 (2015)
Previously, we described a large collection of Minos-Mediated Integration Cassettes (MiMICs) that contain two phiC31 recombinase target sites and allow the generation of a new exon that encodes a protein tag when the MiMIC is inserted in a codon intr
Externí odkaz:
https://doaj.org/article/d0b3068e8f7c46cea2d2e55da0a8619c
Autor:
Sonal Nagarkar-Jaiswal, Pei-Tseng Lee, Megan E Campbell, Kuchuan Chen, Stephanie Anguiano-Zarate, Manuel Cantu Gutierrez, Theodore Busby, Wen-Wen Lin, Yuchun He, Karen L Schulze, Benjamin W Booth, Martha Evans-Holm, Koen JT Venken, Robert W Levis, Allan C Spradling, Roger A Hoskins, Hugo J Bellen
Publikováno v:
eLife, Vol 4 (2015)
Here, we document a collection of ∼7434 MiMIC (Minos Mediated Integration Cassette) insertions of which 2854 are inserted in coding introns. They allowed us to create a library of 400 GFP-tagged genes. We show that 72% of internally tagged proteins
Externí odkaz:
https://doaj.org/article/a360211c69524b5c898cb3e9e9faee55
Publikováno v:
PLoS Genetics, Vol 10, Iss 8, p e1004540 (2014)
Replicated sister chromatids are held in close association from the time of their synthesis until their separation during the next mitosis. This association is mediated by the ring-shaped cohesin complex that appears to embrace the sister chromatids.
Externí odkaz:
https://doaj.org/article/d60872bdc0fd4fbb8d2557312c1494e2
Autor:
Pinhua Wang, Sunayana Sarkar, Zhang Meng Huan, Zhe Zhang, Deepa Balasubramanian, Nandan Jayaram, Sayantan Datta, Ruyu He, Ping Wu, Peng Chao, Ying Zhang, Michael P. Washburn, Laurence Florens, Sonal Nagarkar-Jaiswal, Manish Jaiswal, Man Mohan
DYRK1A, a ubiquitously expressed kinase, is linked to the dominant intellectual developmental disorder, microcephaly and Down syndrome in humans. It regulates numerous cellular processes such cell cycle, vesicle trafficking and microtubule assembly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8d93e692e1b01d464067e48a42e7fdaf
https://doi.org/10.1101/2023.01.18.524493
https://doi.org/10.1101/2023.01.18.524493
Autor:
Rajit Narayanan Cheramangalam, Tarana Anand, Priyanka Pandey, Deepa Balasubramanian, Reshmi Varghese, Neha Singhal, Sonal Nagarkar Jaiswal, Manish Jaiswal
Cells under mitochondrial stress often co-opt mechanisms to maintain energy homeostasis, mitochondrial quality control and cell survival. A mechanistic understanding of such responses is crucial for further insight into mitochondrial biology and dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ce7a60fc49e50111006e064f309f44
https://doi.org/10.1101/2022.10.24.513457
https://doi.org/10.1101/2022.10.24.513457