Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sona Rani, Roy"'
Autor:
Xunwu Hu, Sona Rani Roy, Chengzhi Jin, Guanying Li, Qizheng Zhang, Natsuko Asano, Shunsuke Asahina, Tomoko Kajiwara, Atsushi Takahara, Bolu Feng, Kazuhiro Aoki, Chenjie Xu, Ye Zhang
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Engineering peptide assembly that controls integrin ligand presentation on the molecular level possesses by far the highest ligand density, expanding the perspective of ligand-density-dependent modulation.
Externí odkaz:
https://doaj.org/article/64a809daa2f94225907a1ec1a50239b4
Autor:
Kazi Abdus Salam, Atsushi Furuta, Naohiro Noda, Satoshi Tsuneda, Yuji Sekiguchi, Atsuya Yamashita, Kohji Moriishi, Masamichi Nakakoshi, Hidenori Tani, Sona Rani Roy, Junichi Tanaka, Masayoshi Tsubuki, Nobuyoshi Akimitsu
Publikováno v:
Molecules, Vol 19, Iss 4, Pp 4006-4020 (2014)
The helicase portion of the hepatitis C virus nonstructural protein 3 (NS3) is considered one of the most validated targets for developing direct acting antiviral agents. We isolated polybrominated diphenyl ether (PBDE) 1 from a marine sponge as an N
Externí odkaz:
https://doaj.org/article/eae347ac00ca414684d71b216c0593a4
Publikováno v:
ACS Applied Materials & Interfaces. 13:17236-17242
Heparan sulfate (HS) has important emerging roles in oncogenesis, which represents potential therapeutic strategies for human cancers. However, due to the complexity of the HS signaling network, HS-targeted synthetic cancer therapeutics has never bee
Autor:
William Cortes, Shijin Zhang, Sachie Yukawa, Dingze Mang, Shi Jiao, Shunsuke Asahina, Zhaocai Zhou, Hiroaki Sugasawa, Ye Zhang, Guanying Li, Xunwu Hu, Sona Rani Roy, Pingping Nie
Publikováno v:
Nano Letters. 21:747-755
The Yes-associated protein (YAP) is a major oncoprotein responsible for cell proliferation control. YAP's oncogenic activity is regulated by both the Hippo kinase cascade and uniquely by a mechanical-force-induced actin remodeling process. Inspired b
Autor:
Peni Ahmadi, Junichi Tanaka, Alisa Minei, Idam Hermawan, Sona Rani Roy, Matthew H. Dick, Viqqi Kurnianda
Publikováno v:
Natural Product Research. 36:742-747
Two new steroid sulfates 1 and 2 were obtained from a lipophilic extract of an undescribed bryozoan species in the genus Calyptotheca. The structures of compounds 1 and 2 were elucidated by spectroscopic methods and chemical modifications. Steroids 1
Autor:
Shunsuke Asahina, Sona Rani Roy, Atsushi Takahara, Xunwu Hu, Bolu Feng, Tomoko Kajiwara, Kazuhiro Aoki, Asano Natsuko, Qizheng Zhang, Guanying Li, Chengzhi Jin, Ye Zhang
Advances in mechanistic understanding of integrin-mediated adhesion highlight the importance of precise control of ligand presentation in directing cell migration. Top-down nanopatterning limited the spatial presentation to sub-micron. To enhance it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6084e842eb34ae5e783c9c1007f0f904
https://doi.org/10.1101/2021.09.14.460227
https://doi.org/10.1101/2021.09.14.460227
Autor:
Sona Rani, Roy, Alisa, Minei, Peni, Ahmadi, Idam, Hermawan, Viqqi, Kurnianda, Matthew H, Dick, Junichi, Tanaka
Publikováno v:
Natural product research. 36(3)
Two new steroid sulfates
Publikováno v:
ACS applied materialsinterfaces. 12(17)
Metastasis is one of the ongoing challenges in cancer therapy which most treatments failed to address. Inspired by the upregulated expression of both integrin β1 and heparan sulfate in metastatic tumors, we developed an integrin/HS dual-targeting pe
Publikováno v:
Langmuir : the ACS journal of surfaces and colloids. 36(14)
Malignant brain cancer remains challenging in treatment due to the highly invasive quality of gliomas. Inspired by the upregulated expression of integrin β1 subunits in tumors, we designed and synthesized an integrin-targeting self-assembling ligand
Autor:
Xunwu Hu, Toshio Sasaki, Enming Du, Sona Rani Roy, Ye Zhang, Dingze Mang, Shijin Zhang, Guanying Li
Publikováno v:
Langmuir. 35(23):7376-7382
Inspired by the metamorphosis of pore-forming toxins from soluble inactive monomers to cytolytic trans-membrane assemblies, we developed self-assembly-directed membrane insertion of synthetic analogues for permeability alteration. An expanded pi-conj