Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Sona Legartova"'
Autor:
Soňa Legartová, Alena Svobodová Kovaříková, Jana Běhalová Suchánková, Hana Polášek-Sedláčková, Eva Bártová
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1153-1171 (2022)
RNA methylation, especially 6-methyladenosine (m6A)-modified RNAs, plays a specific role in DNA damage response (DDR). Here, we also observe that RNA modified at 8-methyladenosine (m8A) is recruited to UVA-damaged chromatin immediately after microirr
Externí odkaz:
https://doaj.org/article/57202bccd64143ef8845697dfaf2ada0
Publikováno v:
Life, Vol 12, Iss 6, p 798 (2022)
Background: Variants of linker histone H1 are tissue-specific and are responsible for chromatin compaction accompanying cell differentiation, mitotic chromosome condensation, and apoptosis. Heterochromatinization, as the main feature of these process
Externí odkaz:
https://doaj.org/article/257a422c746f4b6a9def43377b04a775
Autor:
Arigela Harikumar, Raghu Ram Edupuganti, Matan Sorek, Gajendra Kumar Azad, Styliani Markoulaki, Petra Sehnalová, Soňa Legartová, Eva Bártová, Shlomit Farkash-Amar, Rudolf Jaenisch, Uri Alon, Eran Meshorer
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1304-1314 (2017)
Embryonic stem cells (ESCs), with their dual capacity to self-renew and differentiate, are commonly used to study differentiation, epigenetic regulation, lineage choices, and more. Using non-directed retroviral integration of a YFP/Cherry exon into m
Externí odkaz:
https://doaj.org/article/d8c7170f17f64996acc876ed0d2be165
Publikováno v:
Cells, Vol 10, Iss 2, p 297 (2021)
The essential components of splicing are the splicing factors accumulated in nuclear speckles; thus, we studied how DNA damaging agents and A-type lamin depletion affect the properties of these regions, positive on the SC-35 protein. We observed that
Externí odkaz:
https://doaj.org/article/3128938e4e7444a7a59911331cdba6df
Autor:
Alena Svobodová Kovaříková, Lenka Stixová, Aleš Kovařík, Denisa Komůrková, Soňa Legartová, Paolo Fagherazzi, Eva Bártová
Publikováno v:
Cells, Vol 9, Iss 2, p 360 (2020)
The DNA damage response is mediated by both DNA repair proteins and epigenetic markers. Here, we observe that N6-methyladenosine (m6A), a mark of the epitranscriptome, was common in RNAs accumulated at UV-damaged chromatin; however, inhibitors of RNA
Externí odkaz:
https://doaj.org/article/0f0ff6109b3c4db9b21e76b0ad6363a6
Publikováno v:
Stem Cells International, Vol 2017 (2017)
Cajal bodies (CBs) are important compartments containing accumulated proteins that preferentially regulate RNA-related nuclear events, including splicing. Here, we studied the nuclear distribution pattern of CBs in neurogenesis. In adult brains, coil
Externí odkaz:
https://doaj.org/article/41cca016a8704c4c87b0e85176677703
Autor:
Soňa Legartová, Gabriela Lochmanová, Zbyněk Zdráhal, Stanislav Kozubek, Jiří Šponer, Miroslav Krepl, Pavlína Pokorná, Eva Bártová
Publikováno v:
Cells, Vol 8, Iss 9, p 1097 (2019)
The family of heterochromatin protein 1 (HP1) isoforms is essential for chromatin packaging, regulation of gene expression, and repair of damaged DNA. Here we document that γ-radiation reduced the number of HP1α-positive foci, but not HP1β and HP1
Externí odkaz:
https://doaj.org/article/db6c1e9f9a5f46199bac09c13d72220f
Autor:
Eva Bártová, Gabriela Šustáčková, Lenka Stixová, Stanislav Kozubek, Soňa Legartová, Veronika Foltánková
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e27281 (2011)
Oct4 is a specific marker of embryonic stem cell (ESC) pluripotency. However, little is known regarding how Oct4 responds to DNA damage. Here, we investigated whether Oct4 recognizes damaged chromatin in mouse ESCs stably expressing GFP-Oct4. These e
Externí odkaz:
https://doaj.org/article/599e619380da4effba6a947504c296a5
Publikováno v:
Life; Volume 12; Issue 6; Pages: 798
Background: Variants of linker histone H1 are tissue-specific and are responsible for chromatin compaction accompanying cell differentiation, mitotic chromosome condensation, and apoptosis. Heterochromatinization, as the main feature of these process
Methylation of RNAs, especially 6-methyladenosine (m6A)-modified RNAs, plays a specific role in DNA damage response (DDR). Here, we observed that 8-methyladenosine (m8A)-modified RNA is recruited to UVA-microirradiated chromatin, which was reduced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5186e60e9d3edf29d649c532aa3fb81c
https://doi.org/10.21203/rs.3.rs-892499/v1
https://doi.org/10.21203/rs.3.rs-892499/v1