Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Soňa Gurská"'
Autor:
Marianne Fleuti, Tania Sanchez-Quirante, Lenka Poštová Slavětínská, Eva Tloušt'ová, Michal Tichý, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 9, Iss 18, Pp 20557-20570 (2024)
Externí odkaz:
https://doaj.org/article/9fd51b42b0dc460dae1b9022e978c82e
Autor:
Jiří Řehulka, Michal Jurášek, Pavel Dráber, Aleksandra Ivanová, Soňa Gurská, Kateřina Ječmeňová, Olena Mokshyna, Marián Hajdúch, Pavel Polishchuk, Pavel B. Drašar, Petr Džubák
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 39, Iss 1 (2024)
Estradiol dimers (EDs) possess significant anticancer activity by targeting tubulin dynamics. In this study, we synthesised 12 EDs variants via copper-catalysed azide-alkyne cycloaddition (CuAAC) reaction, focusing on structural modifications within
Externí odkaz:
https://doaj.org/article/c6ffcd1be2c54765a90525facd8c6a33
Autor:
Vani Madhuri Velavalapalli, Venkatanarayana Chowdary Maddipati, Soňa Gurská, Narendran Annadurai, Barbora Lišková, Naresh Kumar Katari, Petr Džubák, Marián Hajdúch, Viswanath Das, Rambabu Gundla
Publikováno v:
ACS Omega, Vol 9, Iss 7, Pp 8067-8081 (2024)
Externí odkaz:
https://doaj.org/article/dcac0aed7d23459baaba501d8cac8aec
Autor:
Joyce E. Gutiérrez, Hegira Ramírez, Esteban Fernandez-Moreira, María E. Acosta, Michael R. Mijares, Juan Bautista De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdúch, Liesangerli Labrador-Fagúndez, Bruno G. Stella, Luis José Díaz-Pérez, Gustavo Benaim, Jaime E. Charris
Publikováno v:
Pharmaceuticals, Vol 16, Iss 12, p 1709 (2023)
A series of heterocyclic chloroquine hybrids, containing a chain of two carbon atoms at position four of the quinolinic chain and acting as a link between quinoline and several benzoyl groups, is synthesized and screened in vitro as an inhibitor of
Externí odkaz:
https://doaj.org/article/c3ae8e752e514bfdab501d036bed6509
Autor:
Lucia Veselovská, Radek Pohl, Eva Tloušt′ová, Soňa Gurská, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
ACS Omega, Vol 5, Iss 40, Pp 26278-26286 (2020)
Externí odkaz:
https://doaj.org/article/da63e6d1e1a848d88919a30a79a6038a
Autor:
Joyce E. Gutiérrez, Esteban Fernandez-Moreira, Miguel A. Rodríguez, Michael R. Mijares, Juan Bautista De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdůch, Julia Bruno-Colmenarez, Luis Rojas, Denis Deffieux, Laurent Pouységu, Stéphane Quideau, Jaime Charris, Hegira Ramírez
Publikováno v:
Pharmaceuticals, Vol 15, Iss 10, p 1234 (2022)
A series of 78 synthetic 7-chloro-(4-thioalkylquinoline) derivatives were investigated for cytotoxic activity against eight human cancer as well as 4 non-tumor cell lines. The results showed, with some exceptions, that sulfanyl 5–40 and sulfinyl 41
Externí odkaz:
https://doaj.org/article/ec01600f92cc479f85cac12e2bcbc218
Autor:
Zuleima Blanco, Esteban Fernandez-Moreira, Michael R. Mijares, Carmen Celis, Gricelis Martínez, Juan B. De Sanctis, Soňa Gurská, Petr Džubák, Marián Hajdůch, Ali Mijoba, Yael García, Xenón Serrano, Nahum Herrera, Jhonny Correa-Abril, Yonathan Parra, Jorge Ángel, Hegira Ramírez, Jaime E. Charris
Publikováno v:
Molecules, Vol 27, Iss 17, p 5626 (2022)
The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensively documented. The use of common drugs in the treatment of these pathologies invites us to search for new molecules with these characteristics. In this
Externí odkaz:
https://doaj.org/article/2f9fecb0b6884c4cb8a3b7f2b739e2f1
Autor:
David Kodr, Jarmila Stanková, Michaela Rumlová, Petr Džubák, Jiří Řehulka, Tomáš Zimmermann, Ivana Křížová, Soňa Gurská, Marián Hajdúch, Pavel B. Drašar, Michal Jurášek
Publikováno v:
Biomedicines, Vol 9, Iss 9, p 1104 (2021)
Betulinic acid (BA) is a potent triterpene, which has shown promising potential in cancer and HIV-1 treatment. Here, we report a synthesis and biological evaluation of 17 new compounds, including BODIPY labelled analogues derived from BA. The analogu
Externí odkaz:
https://doaj.org/article/5e863bb72c9b49ad97b6593f6a49c8e3
Autor:
Silvie Rimpelová, Tomáš Zimmermann, Pavel B. Drašar, Bohumil Dolenský, Jiří Bejček, Eva Kmoníčková, Petra Cihlářová, Soňa Gurská, Lucie Kuklíková, Marián Hajdůch, Tomáš Ruml, Lubomír Opletal, Petr Džubák, Michal Jurášek
Publikováno v:
Foods, Vol 10, Iss 1, p 136 (2021)
Cardiac glycosides (CGs) represent a group of sundry compounds of natural origin. Most CGs are potent inhibitors of Na+/K+-ATPase, and some are routinely utilized in the treatment of various cardiac conditions. Biological activities of other lesser k
Externí odkaz:
https://doaj.org/article/be64c88eba2144b19dc471520129a97a
Autor:
Chao Yang, Lenka Poštová Slavětínská, Marianne Fleuti, Blanka Klepetářová, Michal Tichý, Soňa Gurská, Petr Pavliš, Petr Džubák, Marián Hajdúch, Michal Hocek
Publikováno v:
Journal of the American Chemical Society. 144(42)
A new approach for synthesizing polycyclic heterofused 7-deazapurine heterocycles and the corresponding nucleosides was developed based on C-H functionalization of diverse (hetero)aromatics with dibenzothiophene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee85ffc8b8f766a5c73b67f5a6ae8eaf
https://pubmed.ncbi.nlm.nih.gov/36245092
https://pubmed.ncbi.nlm.nih.gov/36245092