Structural Elucidation of a Metagenomic Urethanase and Its Engineering Towards Enhanced Hydrolysis Profiles.

Autor: Bayer T; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Palm GJ; Department of Synthetic & Structural Biochemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Berndt L; Department of Synthetic & Structural Biochemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Meinert H; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Branson Y; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Schmidt L; Department of Pharmaceutical & Medicinal Chemistry Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Str. 17, 17489, Greifswald, Germany., Cziegler C; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Somvilla I; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Zurr C; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Graf LG; Department of Synthetic & Structural Biochemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Janke U; Department of Biophysical Chemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Badenhorst CPS; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., König S; Department of Pharmaceutical & Medicinal Chemistry Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Str. 17, 17489, Greifswald, Germany., Delcea M; Department of Biophysical Chemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Garscha U; Department of Pharmaceutical & Medicinal Chemistry Institute of Pharmacy, University of Greifswald, Friedrich-Ludwig-Jahn-Str. 17, 17489, Greifswald, Germany., Wei R; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Lammers M; Department of Synthetic & Structural Biochemistry Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany., Bornscheuer UT; Department of Biotechnology & Enzyme Catalysis Institute of Biochemistry, University of Greifswald, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Sep 16; Vol. 63 (38), pp. e202404492. Date of Electronic Publication: 2024 Aug 16.

Quantification of increased MUC5AC expression in airway mucus of smoker using an automated image-based approach.

Autor: Groiss S; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Somvilla I; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Daxböck C; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Fuchs J; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Lang-Olip I; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria., Stiegler P; Division of Transplantation Surgery, Department of Surgery, Medical University of Graz, Graz, Austria., Leber B; Division of Transplantation Surgery, Department of Surgery, Medical University of Graz, Graz, Austria., Liegl-Atzwanger B; Diagnostic and Research Institute of Pathology, Diagnostic and Research Center for Molecular for Molecular Biomedicine, Medical University Graz, Graz, Austria., Brislinger D; Division of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.

Publikováno v: Microscopy research and technique [Microsc Res Tech] 2022 Jan; Vol. 85 (1), pp. 5-18. Date of Electronic Publication: 2021 Jul 20.

PHYSIOLOGY AND PATHOPHYSIOLOGY OF HUMAN AIRWAY MUCUS.

Autor: Hill, David B., Button, Brian, Rubinstein, Michael, Boucher, Richard C.

Publikováno v: Physiological Reviews; Oct2022, Vol. 102 Issue 4, p1757-1836, 81p