Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Sompong, Wattanasin"'
Autor:
Rui Zhang, Xiaoyu Shen, JoAnn Dzink-Fox, Brian Hurley, Sompong Wattanasin, Regina E. Cebula, Stefan Peukert, Michael Sabio, Christen Gray, Yingchuan Sun, Jianshi Tao
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1840-1844
Based on a pharmacophore hypothesis substituted tetramic and tetronic acid 3-carboxamides as well as dihydropyridin-2-one-3-carboxamides were investigated as inhibitors of undecaprenyl pyrophosphate synthase (UPPS) for use as novel antimicrobial agen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec10afbbae145de9ee7df1249359217
https://doi.org/10.1016/j.bmcl.2008.02.009
https://doi.org/10.1016/j.bmcl.2008.02.009
Autor:
Sompong, Wattanasin, Joerg, Kallen, Stewart, Myers, Qin, Guo, Michael, Sabio, Claus, Ehrhardt, Rainer, Albert, Ulrich, Hommel, Gisbert, Weckbecker, Karl, Welzenbach, Gabriele, Weitz-Schmidt
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 15:1217-1220
1,4-Diazepane-2,5-diones (2) are found to be a new class of potent LFA-1 inhibitors. The synthesis, structure, and biological evaluation of these 1,4-diazepine-2,5-diones and related derivatives are described.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59f65d17c722f1e9f1c1e00fc6d2f5bf
https://doi.org/10.1016/j.bmcl.2004.11.072
https://doi.org/10.1016/j.bmcl.2004.11.072
Autor:
Constance Friedman, Philip Lake, Gabriele Weitz-Schmidt, Susan Maida, Susan West, Rochdi Bouhel, Ronald Hugo, Sompong Wattanasin, Marla Weetall
Publikováno v:
Analytical Biochemistry. 293:277-287
We have developed a homogeneous high-capacity assay format for measuring integrin- and selectin-dependent cell binding to immobilized ligand using V-well microtiter plates. 2',7'-Bis(2-carboxyethyl)-5-(and-6)-carboxylfluorescence, acetoxymethylester-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91dc079e2814628826c1c698e95fe431
https://doi.org/10.1006/abio.2001.5140
https://doi.org/10.1006/abio.2001.5140
Autor:
Yansong J. Lu, John Bontempo, Frederick Ray Kinder, Sonya Zabludoff, H. Rao Marepalli, Liladhar Murlidhar Waykole, Run-Ming Wang, and David D. Xu, Sompong Wattanasin, Richard William Versace, Kenneth W. Bair, Penny E. Phillips, Long D. Tran, Didier Roche, Green Michael A
Publikováno v:
The Journal of Organic Chemistry. 66:2118-2122
Total syntheses of the cytotoxic marine natural products bengamides B and E are described. Both bengamides are prepared via amide coupling of a protected polyhydroxylated lactone intermediate 9 with a suitably substituted aminocaprolactam intermediat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fc9ec261da2078cc8e3f74191a7410
https://doi.org/10.1021/jo0017133
https://doi.org/10.1021/jo0017133
Autor:
Zia Thale, Ania M. Czuchta, Penny E. Phillips, Miranda L. Sanders, Sompong Wattanasin, Richard William Versace, John Bontempo, Kinder Frederick Ray, Kenneth W. Bair, Phillip Crews
Publikováno v:
The Journal of Organic Chemistry. 66:1733-1741
The structural chemistry and biological activity of the bengamide class of compounds have been further characterized. Extracts prepared from recollected Jaspis cf. coriacea from five sites in Fiji were pooled. Six new bengamides, M (7b), N (8a), O (8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::014307d987e9a66d052328bc0def7d79
https://doi.org/10.1021/jo001380+
https://doi.org/10.1021/jo001380+
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 7:3039-3044
The squalene synthase inhibiting properties of farnesyl diphosphate (FPP) mimics, 3 and related analogues, are described. The results indicate that the nonphosphorus-containing N-hydroxyglycine is a novel replacement for the diphosphate group. Furthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6190e00fe02f18f0749dca4159722bce
https://doi.org/10.1016/s0960-894x(97)10133-0
https://doi.org/10.1016/s0960-894x(97)10133-0
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1951-1954
A series of phosphorus-containing analogs of cholesteryl ester have been synthesized as potential inhibitors of cholesteryl ester transfer protein (CETP). The most potent inhibitor, phosphonate 7 , represents a novel inhibitor of CETP.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7490c555e3bf4e9cdf111aa3a3b50c59
https://doi.org/10.1016/0960-894x(96)00350-2
https://doi.org/10.1016/0960-894x(96)00350-2
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c6f6d7aab9c175988fb4fba5492a24a
https://doi.org/10.1002/chin.199652233
https://doi.org/10.1002/chin.199652233
Publikováno v:
ChemInform. 32
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcad91dc224b1d22953943a291a1da6c
https://doi.org/10.1002/chin.200129198
https://doi.org/10.1002/chin.200129198
Autor:
Kenneth W. Bair, Miranda L. Sanders, Phillip Crews, Zia Thale, Kinder Frederick Ray, Sompong Wattanasin, Richard William Versace, Ania M. Czuchta, Penny E. Phillips, John Bontempo
Publikováno v:
ChemInform. 32
The structural chemistry and biological activity of the bengamide class of compounds have been further characterized. Extracts prepared from recollected Jaspis cf. coriacea from five sites in Fiji were pooled. Six new bengamides, M (7b), N (8a), O (8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4ce6f262bad4db7d930b607bc848f515
https://doi.org/10.1002/chin.200126231
https://doi.org/10.1002/chin.200126231