Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Somnath Singha Roy"'
Autor:
Arup Ranjan Patra, Somnath Singha Roy, Abhishek Basu, Avishek Bhuniya, Arin Bhattacharjee, Subhadip Hajra, Ugir Hossain Sk, Rathindranath Baral, Sudin Bhattacharya
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Abstract A newly designed organoselenium compound, methyl substituted umbelliferone selenocyanate (MUS), was synthesized as a primary hit against the myelotoxic activity of carboplatin. MUS was administered at 6 mg/kg b.wt, p.o. in concomitant and pr
Externí odkaz:
https://doaj.org/article/1c8e2bdf391949c091109c468d6745fe
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S3. Gβ5 promotes chemotherapeutic drug-induced oxidative stress in isolated VCM.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::657f8e9a7ae721ec07a4302afb022864
https://doi.org/10.1158/0008-5472.22418150.v1
https://doi.org/10.1158/0008-5472.22418150.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S4. Gβ5 knockdown obviates mobilization of antioxidant defense systems in VCM exposed to chemotherapeutic drugs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e25bdd5d7eb0e0ab3f0f11849335043
https://doi.org/10.1158/0008-5472.22418147.v1
https://doi.org/10.1158/0008-5472.22418147.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S1. Gβ5 upregulation following chemotherapeutic drug exposure requires new protein synthesis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38ad5d98a3a800033abbc968b246bdb
https://doi.org/10.1158/0008-5472.22418156
https://doi.org/10.1158/0008-5472.22418156
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S8. Gβ5 promotes pathological myocyte-fibroblast crosstalk activated upon chemotherapeutic drug exposure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b23127d7681a68e7dc11fc9690f76591
https://doi.org/10.1158/0008-5472.22418135
https://doi.org/10.1158/0008-5472.22418135
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
The clinical use of multiple classes of cancer chemotherapeutics is limited by irreversible, dose-dependent, and sometimes life-threatening cardiotoxicity. Though distinct in their mechanisms of action, doxorubicin, paclitaxel, and 5-FU all induce ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d253f8b88254e84a0dac7f3d2cc86e6
https://doi.org/10.1158/0008-5472.c.6510047
https://doi.org/10.1158/0008-5472.c.6510047
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S5. Nox-dependent ROS generation promotes activation of CaMKII and ATM following chemotherapy exposure.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4aac9f84978dfc97061b2aab2a6b1bcf
https://doi.org/10.1158/0008-5472.22418144.v1
https://doi.org/10.1158/0008-5472.22418144.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S6. Gβ5 functions in a pathway with ROS, ATM and CAMKII to promote chemotherapeutic drug-induced cardiomyocyte apoptosis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bf35fbdab25a944242b1716781bc986
https://doi.org/10.1158/0008-5472.22418141.v1
https://doi.org/10.1158/0008-5472.22418141.v1
Autor:
Biswanath Maity, Adele Stewart, Sujoy Ghosh, Madhusudan Das, Arnab Ray Chaudhuri, Somnath Singha Roy, Sudipta Saha, Arnab Pramanick, Sreemoyee Chakraborti
Figure S2. Validation of Gβ5-targeted shRNA constructs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97f392fe9a081fce859d80a3259272a
https://doi.org/10.1158/0008-5472.22418153
https://doi.org/10.1158/0008-5472.22418153
Autor:
Sandip Ganguly, Bivas Biswas, Somnath Singha Roy, Joydeep Ghosh, Deepak Dabkara, Rupsa Bakshi
Publikováno v:
Journal of Clinical Oncology. 39:e21043-e21043
e21043 Background: Dacomitinib is an irreversible tyrosine kinase inhibitor of epidermal growth factor receptor (EGFR) approved in advanced non-small cell lung cancer (NSCLC) with mutated EGFR. Literature on real world experience of dacomitinib is la