Tripeptidyl-Peptidase II (TPP II) Inhibitory Activity of (S)-2,3-Dihydro-2-(1H-imidazol-2-yl)-1H-indoles, a Systematic SAR Evaluation. Part 2.

Autor: Breslin, Henry J., Miskowski, Tamara A., Kukla, Michael J., De Winter, Hans L., Somers, Maria V. F., Roevens, Peter W. M., Kavash, Robert W.

Publikováno v: ChemInform; Mar2004, Vol. 35 Issue 12, pno-no, 1p

Design, synthesis, and tripeptidyl peptidase II inhibitory activity of a novel series of (S)-2,3-dihydro-2-(4-alkyl-1H-imidazol-2-yl)-1H-indoles.

Autor: Breslin HJ; Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Welsh and McKean Roads, P.O. Box 776, Spring House, Pennsylvania 19477-0776, USA. HBreslin@prdus.jnj.com, Miskowski TA, Kukla MJ, Leister WH, De Winter HL, Gauthier DA, Somers MV, Peeters DC, Roevens PW

Publikováno v: Journal of medicinal chemistry [J Med Chem] 2002 Nov 21; Vol. 45 (24), pp. 5303-10.