Zobrazeno 1 - 10
of 508
pro vyhledávání: '"Somerharju P"'
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 3, Pp 182-187 (2020)
Abstract Mammalian cells maintain the complex glycerophospholipid (GPL) class compositions of their various membranes within close limits because this is essential to their well‐being or viability. Surprisingly, however, it is still not understood
Externí odkaz:
https://doaj.org/article/c60e25a3381043ef80631d6b8c813f82
Autor:
Kamel El Omari, Sai Li, Abhay Kotecha, Thomas S. Walter, Eduardo A. Bignon, Karl Harlos, Pentti Somerharju, Felix De Haas, Daniel K. Clare, Mika Molin, Felipe Hurtado, Mengqiu Li, Jonathan M. Grimes, Dennis H. Bamford, Nicole D. Tischler, Juha T. Huiskonen, David I. Stuart, Elina Roine
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Lipid membrane fusion is an essential function in many biological processes but little is known about membrane fusion in prokaryotes. The authors here study how haloarchaeal pleomorphic viruses (HRPVs) infect archaeal hosts. The structure-function an
Externí odkaz:
https://doaj.org/article/31855e58b674426b946b1b8cc027fb2e
Akademický článek
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Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Apr . 95(9), 4964-4969.
Externí odkaz:
https://www.jstor.org/stable/44649
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 6, Pp 1259-1264 (2017)
Phosphatidylinositol (PI) is the precursor of many important signaling molecules in eukaryotic cells and, most probably, PI also has important functions in cellular membranes. However, these functions are poorly understood, which is largely due to th
Externí odkaz:
https://doaj.org/article/03e92c7a7c594bbfb0b7b95d3719f38c
Autor:
Matthijs Kol, Radhakrishnan Panatala, Mirjana Nordmann, Leoni Swart, Leonie van Suijlekom, Birol Cabukusta, Angelika Hilderink, Tanja Grabietz, John G.M. Mina, Pentti Somerharju, Sergei Korneev, Fikadu G. Tafesse, Joost C.M. Holthuis
Publikováno v:
Journal of Lipid Research, Vol 58, Iss 5, Pp 962-973 (2017)
SM is a fundamental component of mammalian cell membranes that contributes to mechanical stability, signaling, and sorting. Its production involves the transfer of phosphocholine from phosphatidylcholine onto ceramide, a reaction catalyzed by SM synt
Externí odkaz:
https://doaj.org/article/7063de174e69443c96844c17cd5ebd93
Autor:
Matthijs Kol, Radhakrishnan Panatala, Mirjana Nordmann, Leoni Swart, Leonie van Suijlekom, Birol Cabukusta, Angelika Hilderink, Tanja Grabietz, John G.M. Mina, Pentti Somerharju, Sergei Korneev, Fikadu G. Tafesse, Joost C.M. Holthuis
Publikováno v:
Journal of Lipid Research, Vol 57, Iss 7, Pp 1273-1285 (2016)
SM is a fundamental component of mammalian cell membranes that contributes to mechanical stability, signaling, and sorting. Its production involves the transfer of phosphocholine from phosphatidylcholine onto ceramide, a reaction catalyzed by SM synt
Externí odkaz:
https://doaj.org/article/f750aa0450d64a23921c6eb4b124c2ef
Autor:
Andreas Bickert, Christina Ginkel, Matthijs Kol, Katharina vom Dorp, Holger Jastrow, Joachim Degen, René L. Jacobs, Dennis E. Vance, Elke Winterhager, Xian-Cheng Jiang, Peter Dörmann, Pentti Somerharju, Joost C.M. Holthuis, Klaus Willecke
Publikováno v:
Journal of Lipid Research, Vol 56, Iss 4, Pp 821-835 (2015)
Besides bulk amounts of SM, mammalian cells produce small quantities of the SM analog ceramide phosphoethanolamine (CPE). Little is known about the biological role of CPE or enzymes responsible for CPE production. Heterologous expression studies reve
Externí odkaz:
https://doaj.org/article/b55343a153c440909b926aa8cdb55ae3
Publikováno v:
Bio-Protocol, Vol 7, Iss 9 (2017)
Glycerophospholipids consist of a glycerophosphate backbone to which are esterified two acyl chains and a polar head group. The head group (e.g., choline, ethanolamine, serine or inositol) defines the glycerophospholipid class, while the acyl chains
Externí odkaz:
https://doaj.org/article/62a3d6f8d9084830a77296da245d331f
Publikováno v:
Journal of Lipid Research, Vol 51, Iss 12, Pp 3533-3541 (2010)
Previous studies indicate that methyl-β-cyclodextrin (meβ-CD) can greatly enhance translocation of long-chain phospholipids from vesicles to cells in culture, which is very useful when studying, e.g., phospholipid metabolism and trafficking. Howeve
Externí odkaz:
https://doaj.org/article/1e0de7984b80415c9630261033641adb