Zobrazeno 1 - 10
of 491
pro vyhledávání: '"Somdutt"'
Autor:
Mohamed El fadili, Mohammed Er-rajy, Somdutt Mujwar, Abduljelil Ajala, Rachid Bouzammit, Mohammed Kara, Hatem A. Abuelizz, Sara Er-rahmani, Menana Elhallaoui
Publikováno v:
BMC Chemistry, Vol 18, Iss 1, Pp 1-22 (2024)
Abstract Based on a structural family of thirty-two NR2B-selective N-Methyl-D-Aspartate receptor (NMDAR) antagonists, two phenylpiperazine derivatives labeled C37 and C39 were conceived thanks to molecular modeling techniques, as novel NMDAR inhibito
Externí odkaz:
https://doaj.org/article/68b2ece01da4488b885bf6c3bc083b71
Autor:
Mateusz Kciuk, Anjali Garg, Manni Rohilla, Rishabh Chaudhary, Sanchit Dhankhar, Sachin Dhiman, Seema Bansal, Monika Saini, Thakur Gurjeet Singh, Samrat Chauhan, Somdutt Mujwar, Adrianna Gielecińska, Renata Kontek
Publikováno v:
Antioxidants, Vol 13, Iss 7, p 775 (2024)
Rheumatoid arthritis (RA) is a persistent autoimmune disorder that is characterized by joint inflammation, discomfort, and impairment. Despite the existence of several therapeutic approaches, their effectiveness is often restricted and may be linked
Externí odkaz:
https://doaj.org/article/0ed4c67fe47545928b5fbe4bcdc2cc0b
Autor:
Mateusz Kciuk, Nitika Garg, Sanchit Dhankhar, Monika Saini, Somdutt Mujwar, Sushma Devi, Samrat Chauhan, Thakur Gurjeet Singh, Randhir Singh, Beata Marciniak, Adrianna Gielecińska, Renata Kontek
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 701 (2024)
Neurodegenerative diseases (Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and others) and cancer, seemingly disparate in their etiology and manifestation, exhibit intriguing associations in certain cellular and molecular proce
Externí odkaz:
https://doaj.org/article/7bad4445312c461f8a591f45b257cb20
Autor:
Rachid Bouzammit, Salim Belchkar, Mohamed El fadili, Youssra Kanzouai, Somdutt Mujwar, Mohammed M. Alanazi, Mohammed Chalkha, Asmae Nakkabi, Mohamed Bakhouch, Emese Gal, Luiza Ioana Gaina, Ghali al houari
Publikováno v:
Molecules, Vol 29, Iss 11, p 2510 (2024)
Novel isoxazole–triazole conjugates have been efficiently synthesized using 3-formylchromone as starting material according to a multi-step synthetic approach. The structures of the target conjugates and intermediate products were characterized by
Externí odkaz:
https://doaj.org/article/b96662f3f42f4b3aa825af06c89a9e83
Autor:
Ravinder Singh, Varinder Singh, Md. Altamash Ahmad, Chirag Pasricha, Pratima Kumari, Thakur Gurjeet Singh, Rupinder Kaur, Somdutt Mujwar, Tanveer A. Wani, Seema Zargar
Publikováno v:
Pharmaceuticals, Vol 17, Iss 4, p 454 (2024)
Inflammation is a distinguished clinical manifestation of COVID-19 and type 2 diabetes mellitus (T2DM), often associated with inflammatory dysfunctions, insulin resistance, metabolic dysregulation, and other complications. The present study aims to t
Externí odkaz:
https://doaj.org/article/d7ea81eae349449fa08b0d9b26ea9c72
Autor:
Kirti Sharma, Manjinder Singh, Pratibha Sharma, Sumesh C. Sharma, Somdutt Mujwar, Mohit Kapoor, Krishna Kumar Mishra, Tanveer A. Wani
Publikováno v:
Molecules, Vol 29, Iss 6, p 1406 (2024)
SARS-CoV, an RNA virus, is contagious and displays a remarkable degree of adaptability, resulting in intricate disease presentations marked by frequent genetic mutations that can ultimately give rise to drug resistance. Targeting its viral replicatio
Externí odkaz:
https://doaj.org/article/2a42876fa0324a53a90033f23b733da0
Autor:
Mohammed Er-rajy, Mohamed El fadili, Somdutt Mujwar, Hamada Imtara, Omkulthom Al kamaly, Samar Zuhair Alshawwa, Fahd A. Nasr, Sara Zarougui, Menana Elhallaoui
Publikováno v:
Arabian Journal of Chemistry, Vol 16, Iss 10, Pp 105193- (2023)
The overexpression of cyclooxygenase-2 (COX-2) was clearly associated with carcinogenesis, and COX-2 as a possible target has long been exploited for cancer therapy. A group of 29 derivatives of 1, 5-diarylpyrazole was used to study its structural re
Externí odkaz:
https://doaj.org/article/d263a7bee01d4b1f9c226eceb1bf3da7
Publikováno v:
Journal of Forensic Science and Medicine, Vol 9, Iss 1, Pp 70-75 (2023)
India has more than 4500 distinct population which are different based on caste, tribe, religion, locations, physical features, social beliefs, and language. Genome India project was approved in February 2020 by the Ministry of Science and Technology
Externí odkaz:
https://doaj.org/article/1366153d73aa4ef09b88c69a066b22d8
Autor:
Mateusz Kciuk, Adrianna Gielecińska, Somdutt Mujwar, Mariusz Mojzych, Beata Marciniak, Rafał Drozda, Renata Kontek
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1278-1298 (2022)
Carbonic anhydrases IX and CAXII (CAIX/CAXII) are transmembrane zinc metalloproteins that catalyze a very basic but crucial physiological reaction: the conversion of carbon dioxide into bicarbonate with a release of the proton. CA, especially CAIX an
Externí odkaz:
https://doaj.org/article/4aa6f40ea1f64622b22fec14a3440c6a
Autor:
Muhammed Amanat, Swati Gautam, Rishabh Chalotra, Kanhaiya Lal, Tanya Gupta, Rohini Agrawal, Somdutt Mojwar, Randhir Singh
Publikováno v:
Pharmacological Research - Modern Chinese Medicine, Vol 7, Iss , Pp 100258- (2023)
Introduction: A perennial, aromatic, tuberose plant Zingiber roseum (Roscoe.) (Zingiberaceae), flourishes in tropical and subtropical climates. In Traditional Chinese Medicine, several pharmacological properties of Zingiber roseum have been reported
Externí odkaz:
https://doaj.org/article/3920a78bd4cf449585b5cd1d7a0156db