Beneficial effects of the combination of BCc1 and Hep-S nanochelating-based medicines on IL-6 in hospitalized moderate COVID-19 adult patients: a randomized, double-blind, placebo-controlled clinical trial

Autor: Maryam Hafizi, Somayeh Kalanaky, Saideh Fakharzadeh, Pegah Karimi, Atefeh Fakharian, Somayeh Lookzadeh, Esmaeil Mortaz, Maryam Sadat Mirenayat, Jalal Heshmatnia, Mehrdad Bakhshayesh Karam, Homa Zamani, Alireza Nadji, Mihan Pourabdollah Toutkaboni, Saeed Oraee-Yazdani, Mohammad Esmaeil Akbari, Hamidreza Jamaati, Mohammad Hassan Nazaran

Publikováno v: Trials, Vol 24, Iss 1, Pp 1-15 (2023)

Abstract Background In the severe forms of COVID-19 and many other infectious diseases, the patients develop a cytokine storm syndrome (CSS) where pro-inflammatory cytokines such as IL-6 and TNF-α play a key role in the development of this serious p

Externí odkaz: https://doaj.org/article/99951f6850c74caaa844a52adb5e5cea

Decreased serum levels of angiotensin converting enzyme (ACE)2 and enhanced cytokine levels with severity of COVID-19: normalisation upon disease recovery

Autor: Esmaeil Mortaz, Hamidreza Jamaati, Neda Dalil Roofchayee, Hakime Sheikhzade, Maryam Mirenayat, Mohsen Sadeghi, Somayeh Lookzadeh, Neda K. Dezfuli, Gert Folkerts, Sharon Mumby, Johan Garssen, Ian M. Adcock

Publikováno v: Heliyon, Vol 8, Iss 2, Pp e08957- (2022)

Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Circulating soluble angiotensin-converting enzyme (sACE2)2, the main receptor for SARS-CoV-2, together with components of the renin-a

Externí odkaz: https://doaj.org/article/c951173a3452467ab61c415d70a1dca4

Atorvastatin versus Placebo in ICU Patients with COVID-19: Ninety-day Results of the INSPIRATION-S Trial

Autor: Azita H. Talasaz, Parham Sadeghipour, Hooman Bakhshandeh, Babak Sharif-Kashani, Farid Rashidi, Mohammad Taghi Beigmohammadi, Keivan Gohari Moghadam, Somaye Rezaian, Ali Dabbagh, Seyed Hashem Sezavar, Mohsen Farrokhpour, Atefeh Abedini, Rasoul Aliannejad, Taghi Riahi, Mahdi Yadollahzadeh, Somayeh Lookzadeh, Parisa Rezaeifar, Samira Matin, Ouria Tahamtan, Keyhan Mohammadi, Elnaz Zoghi, Hamid Rahmani, Seyed Hossein Hosseini, Seyed Masoud Mousavian, Homa Abri, Pardis Sadeghipour, Elahe Baghizadeh, Farnaz Rafiee, Sepehr Jamalkhani, Ahmad Amin, Bahram Mohebbi, Seyed Ehsan Parhizgar, Mahshid Soleimanzadeh, Maryam Aghakouchakzadeh, Vahid Eslami, Pooya Payandemehr, Hossein Khalili, Hamed Talakoob, Taranom Tojari, Shadi Shafaghi, Sanaz Tabrizi, Hessam Kakavand, Alireza Kashefizadeh, Atabak Najafi, David Jimenez, Aakriti Gupta, Mahesh V. Madhavan, Sanjum S. Sethi, Sahil A. Parikh, Manuel Monreal, Naser Hadavand, Alireza Hajighasemi, Khalil Ansarin, Majid Maleki, Saeed Sadeghian, Stefano Barco, Bob Siegerink, Erica S. Spatz, Gregory Piazza, Ajay J. Kirtane, Benjamin W. Van Tassell, Gregory Y. H. Lip, Frederikus A. Klok, Samuel Z. Goldhaber, Gregg W. Stone, Harlan M. Krumholz, Behnood Bikdeli

Publikováno v: Talasaz, A H, Sadeghipour, P, Bakhshandeh, H, Sharif-Kashani, B, Rashidi, F, Beigmohammadi, M T, Moghadam, K G, Rezaian, S, Dabbagh, A, Sezavar, S H, Farrokhpour, M, Abedini, A, Aliannejad, R, Riahi, T, Yadollahzadeh, M, Lookzadeh, S, Rezaeifar, P, Matin, S, Tahamtan, O, Mohammadi, K, Zoghi, E, Rahmani, H, Hosseini, S H, Mousavian, S M, Abri, H, Sadeghipour, P, Baghizadeh, E, Rafiee, F, Jamalkhani, S, Amin, A, Mohebbi, B, Parhizgar, S E, Soleimanzadeh, M, Aghakouchakzadeh, M, Eslami, V, Payandemehr, P, Khalili, H, Talakoob, H, Tojari, T, Shafaghi, S, Tabrizi, S, Kakavand, H, Kashefizadeh, A, Najafi, A, Jimenez, D, Gupta, A, Madhavan, M V, Sethi, S S, Parikh, S A, Monreal, M, Hadavand, N, Hajighasemi, A, Ansarin, K, Maleki, M, Sadeghian, S, Barco, S, Siegerink, B, Spatz, E S, Piazza, G, Kirtane, A J, Tassell, B W V, Lip, G Y H, Klok, F A, Goldhaber, S Z, Stone, G W, Krumholz, H M & Bikdeli, B 2023, ' Atorvastatin versus Placebo in ICU Patients with COVID-19 : Ninety-day Results of the INSPIRATION-S Trial ', Thrombosis and Haemostasis, vol. 123, no. 7, pp. 723-733 . https://doi.org/10.1055/a-2059-4844

Background In the INSPIRATION-S trial, atorvastatin versus placebo was associated with a nonsignificant 16% reduction in 30-day composite of venous/arterial thrombosis or death in intensive care unit (ICU) patients with COVID-19. Thrombo-inflammatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6859407a208bfb41a09e412609ae4f85
https://doi.org/10.1055/a-2059-4844

Asthma induces psychiatric impairments in association with default mode and salience networks alteration:A resting-state EEG study

Autor: Leila Gholami-Mahtaj, Morteza Salimi, Milad Nazari, Farhad Tabasi, Sobhan Bamdad, Kolsoum Dehdar, Mohammad Mikaili, Seyed Alireza Mahdaviani, Fereshteh Salari, Somayeh Lookzadeh, Hamidreza Jamaati, Alireza Salimi, Mohammad Reza Raoufy

Publikováno v: Gholami-Mahtaj, L, Salimi, M, Nazari, M, Tabasi, F, Bamdad, S, Dehdar, K, Mikaili, M, Mahdaviani, S A, Salari, F, Lookzadeh, S, Jamaati, H, Salimi, A & Raoufy, M R 2022, ' Asthma induces psychiatric impairments in association with default mode and salience networks alteration : A resting-state EEG study ', Respiratory Physiology and Neurobiology, vol. 300, 103870 . https://doi.org/10.1016/j.resp.2022.103870

Asthma is a chronic inflammatory disease associated with a high prevalence of psychiatric disorders. There are specific brain networks responsible for emotional processes, including two important networks associated with psychiatric problems: the def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82cf76c09e604c3da8f1f28eeb1a5296
https://pure.au.dk/portal/da/publications/asthma-induces-psychiatric-impairments-in-association-with-default-mode-and-salience-networks-alteration(7c5f75ee-f677-4ed8-aeb2-02741cf46a66).html

Intermediate-Dose versus Standard-Dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to the Intensive Care Unit:90-Day Results from the INSPIRATION Randomized Trial

Autor: Samuel Z. Goldhaber, Naser Hadavand, Aakriti Gupta, Ajay J. Kirtane, Samira Matin, Seyed Ehsan Parhizgar, Gregory Piazza, Mahesh V. Madhavan, Babak Sharif-Kashani, Benjamin W. Van Tassell, Sahil A. Parikh, Parisa Rezaeifar, Vahid Eslami, Homa Abri, Sanaz Hariri Tabrizi, Mohammad Taghi Beigmohammadi, Atabak Najafi, Paul P. Dobesh, Seyed Hossein Hosseini, Farid Rashidi, Hossein Khalili, Bahram Mohebbi, Ali Dabbagh, Manuel Monreal, Behnood Bikdeli, Hooman Bakhshandeh, Elnaz Zoghi, Rasoul Aliannejad, Majid Maleki, Farnaz Rafiee, Atefeh Abedini, Gregory Y.H. Lip, Samrand Fattah Ghazi, Keivan Gohari Moghadam, Pooya Payandemehr, Shadi Shafaghi, Seyed Masoud Mousavian, Alireza Kashefizadeh, Mahdi Yadollahzadeh, Mohsen Farrokhpour, Shaghayegh Shahmirzaei, Ouria Tahamtan, Sepehr Jamalkhani, Gregg W. Stone, Parham Sadeghipour, Azita Hajhossein Talasaz, Alireza Hajighasemi, David Jiménez, Harlan M. Krumholz, Hamid Reza Rahmani, Sanjum S. Sethi, Ahmad Amin, Hessam Kakavand, Somayeh Lookzadeh, Pardis Sadeghipour, Elahe Baghizadeh, Saeed Sadeghian, Seyed Hashem Sezavar, Taghi Riahi, Keyhan Mohammadi

Publikováno v: Bikdeli, B, Talasaz, A H, Rashidi, F, Bakhshandeh, H, Rafiee, F, Rezaeifar, P, Baghizadeh, E, Matin, S, Jamalkhani, S, Tahamtan, O, Sharif-Kashani, B, Beigmohammadi, M T, Farrokhpour, M, Sezavar, S H, Payandemehr, P, Dabbagh, A, Moghadam, K G, Khalili, H, Yadollahzadeh, M, Riahi, T, Abedini, A, Lookzadeh, S, Rahmani, H, Zoghi, E, Mohammadi, K, Sadeghipour, P, Abri, H, Tabrizi, S, Mousavian, S M, Shahmirzaei, S, Amin, A, Mohebbi, B, Parhizgar, S E, Aliannejad, R, Eslami, V, Kashefizadeh, A, Dobesh, P P, Kakavand, H, Hosseini, S H, Shafaghi, S, Ghazi, S F, Najafi, A, Jimenez, D, Gupta, A, Madhavan, M V, Sethi, S S, Parikh, S A, Monreal, M, Hadavand, N, Hajighasemi, A, Maleki, M, Sadeghian, S, Piazza, G, Kirtane, A J, Van Tassell, B W, Stone, G W, Lip, G Y H, Krumholz, H M, Goldhaber, S Z & Sadeghipour, P 2022, ' Intermediate-Dose versus Standard-Dose Prophylactic Anticoagulation in Patients with COVID-19 Admitted to the Intensive Care Unit : 90-Day Results from the INSPIRATION Randomized Trial ', Thrombosis and Haemostasis, vol. 122, no. 1, pp. 131-141 . https://doi.org/10.1055/a-1485-2372
Thrombosis And Haemostasis
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Background Thrombotic complications are considered among the main extrapulmonary manifestations of coronavirus disease 2019 (COVID-19). The optimal type and duration of prophylactic antithrombotic therapy in these patients remain unknown. Methods Thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e5e2e13e348ec82f749b945eb68309d
https://vbn.aau.dk/da/publications/c9500d65-d410-4abc-9a95-21ac6f2607ef