Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Somayeh Pouyanfard"'
Autor:
Hamidreza Hashemi, Somayeh Pouyanfard, Mojgan Bandehpour, Zahra Noroozbabaei, Bahram Kazemi, Xavier Saelens, Talat Mokhtari-Azad
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45765 (2012)
Considering the emergence of highly pathogenic influenza viruses and threat of worldwide pandemics, there is an urgent need to develop broadly-protective influenza vaccines. In this study, we demonstrate the potential of T7 bacteriophage-based nanopa
Externí odkaz:
https://doaj.org/article/b681775806df406ba474b07003c04b99
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49539 (2012)
We report here the development of multivalent T7 bacteriophage nanoparticles displaying an immunodominant H-2k(d)-restricted CTL epitope derived from the rat HER2/neu oncoprotein. The immunotherapeutic potential of the chimeric T7 nanoparticles as an
Externí odkaz:
https://doaj.org/article/9042daa8253845b0984c783d0fdd4bfb
Publikováno v:
Blood. 140:7390-7391
Publikováno v:
Experimental Hematology. 71:13-23
Mouse and human pluripotent stem cells have been widely used to study the development of the hematopoietic and immune systems. While not all cells can be derived with the same efficiency, immune cells such as natural killer (NK) cells and macrophages
Publikováno v:
Cancer Research. 82:553-553
Despite many recent advances, treatment of acute myeloid leukemia (AML) remains challenging. To generate an improved cell-based therapy against AML, our group has produced NK cells from induced pluripotent stem cells (iPSCs). iPSC-derived NK cells ef
Autor:
Tatiana Kisseleva, Karin Diggle, Timothy V. Pham, Pablo Tamayo, Dan S. Kaufman, Andrea Fanjul, Hamidreza Hashemi, Luisjesus S. Cruz, Manuel Fierro, Somayeh Pouyanfard, Nairika Meshgin
Publikováno v:
Stem cells (Dayton, Ohio), vol 39, iss 12
With an increasing number of patients with degenerative hepatic diseases, such as liver fibrosis, and a limited supply of donor organs, there is an unmet need for therapies that can repair or regenerate damaged liver tissue. Treatment with macrophage
Publikováno v:
Blood, vol 138, iss Supplement 1
Previous studies by our group demonstrate the ability to routinely derive hematopoietic and immune cells from human pluripotent stem cells. Here, we demonstrate the efficient derivation of macrophages from human induced pluripotent stem cells (iPSCs)
iPSC-Derived Natural Killer Cells and Macrophages Synergistically Kill Acute Myeloid Leukemia Blasts
Publikováno v:
Blood. 138:1692-1692
Despite many advances, the treatment of acute myeloid leukemia (AML) remains challenging, and few patients are cured by therapies other than allogeneic hematopoietic cell transplant. Treatment with natural killer (NK) cells from allogeneic donors is
Autor:
Pooja Vinay, Rachel Langland, Jennifer Govero, Nitin Mahajan, Anna Ballard, Andrew Martens, Liz Schwarzkopf, Tom Leedom, David H. Spencer, Somayeh Pouyanfard, Andrew Espenschied, Alexander S. Hamil, Kenneth M Chrobak, Matthew L. Cooper, Ayman Kabakibi, Michael R. James
Publikováno v:
Blood. 138:2772-2772
Background T-cell Acute Lymphoblastic Leukemia (T-ALL) / Lymphoblastic Lymphoma (LBL) represent a class of devastating hematologic cancers with high rates of relapse and mortality in both children and adults. Development of CAR-T cell therapies for T
Autor:
Gloria Spagnoli, Somayeh Pouyanfard, Stefano Maggi, Simone Ottonello, Elena Canali, Massimo Tommasino, Davide Cavazzini, Angelo Bolchi, Martin Müller
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Vaccines targeting the human papillomavirus (HPV) minor capsid protein L2 are emerging as chemico-physically robust and broadly protective alternatives to the current HPV (L1-VLP) vaccines. We have previously developed a trivalent L2 vaccine prototyp