Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Somanon Bhattacharya"'
Autor:
Natalia Kronbauer Oliveira, Kyungyoon Yoo, Somanon Bhattacharya, Rina Gambhir, Nigina Kirgizbaeva, Pilar Arcones García, Ignacio Pompa Prados, Caroline Mota Fernandes, Maurizio Del Poeta, Bettina C. Fries
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Cryptococcus neoformans (Cn) is an opportunistic yeast that causes meningoencephalitis in immunocompromised individuals. Calorie restriction (CR) prolongs Cn replicative lifespan (RLS) and mimics low-glucose environments in which Cn resides
Externí odkaz:
https://doaj.org/article/78c0f3c0c09d423cb4a64e7faae09013
Autor:
Kasturi Banerjee, Michael P. Motley, Camila Boniche-Alfaro, Somanon Bhattacharya, Raj Shah, Andrew Ardizzone, Bettina C. Fries
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 4 (2022)
ABSTRACT The most pressing challenge for the development of anti-capsular antibodies is maximizing coverage against the heterogenous capsular polysaccharide (CPS) of carbapenem-resistant Klebsiella pneumoniae (CR-Kp). So far, only CR-Kp with wzi154 C
Externí odkaz:
https://doaj.org/article/2f5969ee3e46430eb522014b2f613fdf
Autor:
Vanessa K. A. Silva, Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Daniel Zamith-Miranda, Joshua D. Nosanchuk, Bettina C. Fries
Publikováno v:
mBio, Vol 13, Iss 1 (2022)
ABSTRACT Replicative aging is an underexplored field of research in medical mycology. Cryptococcus neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal invasive infections. The fungal cell wall is essential for yeas
Externí odkaz:
https://doaj.org/article/254adcc416374002bd625ca8e9cbf4bb
Autor:
Natalia Kronbauer Oliveira, Somanon Bhattacharya, Rina Gambhir, Manav Joshi, Bettina C. Fries
Publikováno v:
Journal of Fungi, Vol 8, Iss 7, p 677 (2022)
Cryptococcus neoformans causes meningoencephalitis in immunocompromised individuals, which is treated with fluconazole (FLC) monotherapy when resources are limited. This can lead to azole resistance, which can be mediated by overexpression of ABC tra
Externí odkaz:
https://doaj.org/article/0104b70716b84962a97dd42bf3159e3b
Autor:
Erika P. Orner, Somanon Bhattacharya, Klea Kalenja, Danielle Hayden, Maurizio Del Poeta, Bettina C. Fries
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
As Cryptococcus neoformans mother cells generationally age, their cell walls become thicker and cell-wall associated virulence factors are upregulated. Antiphagocytic protein 1 (App1), and laccase enzymes (Lac1 and Lac2) are virulence factors known t
Externí odkaz:
https://doaj.org/article/54213505d0d94c35ae0144cd42c61f5c
Autor:
Somanon Bhattacharya, Natalia Kronbauer Oliveira, Anne G. Savitt, Vanessa K. A. Silva, Rachel B. Krausert, Berhane Ghebrehiwet, Bettina C. Fries
Publikováno v:
Journal of Fungi, Vol 7, Iss 6, p 489 (2021)
Chronic meningoencephalitis is caused by Cryptococcus neoformans and is treated in many parts of the world with fluconazole (FLC) monotherapy, which is associated with treatment failure and poor outcome. In the host, C. neoformans propagates predomin
Externí odkaz:
https://doaj.org/article/666f46a3ccc649e7af43f5a2f05ed2bb
Publikováno v:
Journal of Fungi, Vol 7, Iss 1, p 6 (2020)
Candida albicans, Candida auris, Candida glabrata, and Cryptococcus neoformans are pathogenic yeasts which can cause systemic infections in immune-compromised as well as immune-competent individuals. These yeasts undergo replicative aging analogous t
Externí odkaz:
https://doaj.org/article/1060cfe4142b47af8d3062ef06562ae6
Publikováno v:
Antibiotics, Vol 9, Iss 6, p 312 (2020)
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common. These are pathogenic yeast and are usually present in the normal microbio
Externí odkaz:
https://doaj.org/article/671e0fc5c11e4e2fb2c20bccf091738e
Publikováno v:
mBio, Vol 9, Iss 4 (2018)
ABSTRACT Ergosterol (ERG) is a critical sterol in the cell membranes of fungi, and its biosynthesis is tightly regulated by 25 known enzymes along the ERG production pathway. The effects of changes in expression of each ERG biosynthesis enzyme in Sac
Externí odkaz:
https://doaj.org/article/c3f1bbde2b7e4472b74e0932c31f0805
Autor:
Kasturi Banerjee, Michael P. Motley, Camila Boniche-Alfaro, Somanon Bhattacharya, Raj Shah, Andrew Ardizzone, Bettina C. Fries
Publikováno v:
Microbiology Spectrum. 10
Here, we presentin vitroandin vivodata for thewzi50CPS-specific monoclonal antibody MAb 24D11, demonstrating its cross-protective efficacy against three prominentwintypes (wzi29,wzi154, andwzi50) of the carbapenem-resistant clonal group CG258. In a m