Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Somanathapura K. NaveenKumar"'
Autor:
Gajanan D. Katkar, Mahalingam S. Sundaram, Somanathapura K. NaveenKumar, Basavarajaiah Swethakumar, Rachana D. Sharma, Manoj Paul, Gopalapura J. Vishalakshi, Sannaningaiah Devaraja, Kesturu S. Girish, Kempaiah Kemparaju
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
The saw-scaled viper venom causes continued tissue damage that may cause death. Here the authors show that the venom attracts neutrophils to the bite site and induces neutrophil extracellular traps that capture venom components causing tissue damage,
Externí odkaz:
https://doaj.org/article/e5a4eac896c04b2da861157c352e0645
Autor:
Somanathapura K. NaveenKumar, Mahadevappa Hemshekhar, Bidare N. Sharathbabu, Kempaiah Kemparaju, Govindasamy Mugesh, Kesturu S. Girish
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1869:166688
Publikováno v:
Nature Reviews Rheumatology. 18:675-676
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1865:2303-2316
Reactive oxygen species (ROS) are capable of inducing cell death or apoptosis. Recently, we demonstrated that lipid-ROS can mediate ferroptosis and activation of human platelets. Ferroptosis is an intracellular iron-mediated cell death, distinct from
Publikováno v:
ACS chemical biology. 15(10)
Red blood cell death or erythrocyte apoptosis (eryptosis) is generally mediated by oxidative stress, energy depletion, heavy metals exposure, or xenobiotics. As erythrocytes are a major target for oxidative stress due to their primary function as O2-
Publikováno v:
Angewandte Chemie (International ed. in English). 60(6)
Nanoparticles that functionally mimic the activity of metal-containing enzymes (metallo-nanozymes) are of therapeutic importance for treating various diseases. However, it is still not clear whether such nanozymes can completely substitute the functi
Autor:
K.S. Girish, Gopalapura J. Vishalakshi, Swamy Jagadish, Mahadevappa Hemshekhar, Kurnegala Manikanta, Somanathapura K. NaveenKumar, Kempaiah Kemparaju
Publikováno v:
Journal of Pineal Research. 69
Melatonin is a chronobiotic hormone, which can regulate human diseases like cancer, atherosclerosis, respiratory disorders, and microbial infections by regulating redox system. Melatonin exhibits innate immunomodulation by communicating with immune s
Autor:
Mahadevappa Hemshekhar, Gopalapura J. Vishalakshi, Kempaiah Kemparaju, Somanathapura K. NaveenKumar, Madegowda Mahendra, K.S. Girish
Publikováno v:
Environmental Toxicology. 34:262-270
The catecholic derivative para-tertiary butyl catechol (PTBC) is a conventional antioxidant and polymerization inhibitor, which exhibits melanocytotoxic effects and contact dermatitis often leading to occupational leucoderma or vitiligo. Although num
Autor:
Mahadevappa Hemshekhar, Kesturu S. Girish, Somanathapura K. NaveenKumar, Bidare N SharathBabu, Govindasamy Mugesh, Kempaiah Kemparaju
Publikováno v:
ACS Chemical Biology. 13:1996-2002
Hemolysis, a process by which the destruction of red blood cells leads to the release of hemoglobin, is a critical event observed during hemolytic disorders. Under oxidative stress conditions, hemoglobin can release its heme prosthetic group, which i
Autor:
Kesturu S. Girish, Kempaiah Kemparaju, Somanathapura K. NaveenKumar, Mahalingam S. Sundaram, Mahadevappa Hemshekhar
Publikováno v:
Biochemical and Biophysical Research Communications. 491:183-191
Cell-free hemoglobin (Hb), a well-known marker of intravascular hemolysis, is eventually oxidized to methemoglobin (MtHb). Elevated levels of MtHb have been noted, alongside depleted levels of platelets, in several hemolytic diseases. The current stu