Výsledky vyhledávání - "Somaia I. Masoud"

RETRACTED: Molecular mechanisms of neuroprotective effect of adjuvant therapy with phenytoin in pentylenetetrazole-induced seizures: Impact on Sirt1/NRF2 signaling pathways

Autor: Amani E. Khalifa, Rania M. Rahmo, Somaia I. Masoud, Hadwa Ali Abd Al-khalek, Nagwa Ali Sabri, Marwa M. Nagib, Mariane G. Tadros

Publikováno v: NeuroToxicology. 68:47-65

Current anticonvulsant therapies are principally aimed at suppressing neuronal hyperexcitability to prevent or control the incidence of seizures. However, the role of oxidative stress processes in seizures led to the proposition that antioxidant comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5724a9ad11edb962e432e39220a25b5
https://doi.org/10.1016/j.neuro.2018.07.006

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Nitric oxide is involved in ibuprofen preemptive analgesic effect in the plantar incisional model of postsurgical pain in mice

Autor: May Hamza, Sherin S.T. Saad, Somaia I. Masoud, Mohamed H. Bahr

Publikováno v: Neuroscience Letters. 614:33-38

Control of postoperative pain is far from satisfactory. Yet, non-steroidal anti-inflammatory drugs (NSAIDs) remain an important choice. The production of nitric oxide (NO), which plays an important role in the development and maintenance of inflammat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124f53534eaac2d8930c88a5287db8d9
https://doi.org/10.1016/j.neulet.2015.12.034

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Ameliorative Effects of α-Tocopherol and/or Coenzyme Q10 on Phenytoin-Induced Cognitive Impairment in Rats: Role of VEGF and BDNF-TrkB-CREB Pathway

Autor: Nagwa Ali Sabri, Rania M. Rahmo, Marwa M. Nagib, Somaia I. Masoud, Amani E. Khalifa, Mariane G. Tadros

Publikováno v: Neurotoxicity research. 35(2)

Phenytoin is one of the most well-known antiepileptic drugs that cause cognitive impairment which is closely related to cAMP response element-binding protein (CREB) brain-derived neurotrophic factor (BDNF) signaling pathway. Moreover, vascular endoth

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::247bf90864d576dba4dd62bc9dfe29a8
https://pubmed.ncbi.nlm.nih.gov/30374909

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Prophylactic L-arginine and ibuprofen delay the development of tactile allodynia and suppress spinal miR-155 in a rat model of diabetic neuropathy

Autor: Marwa Matboli, Wesam M. El-Bakly, May Hamza, Hadwa A. Abd-Alkhalek, Ghada M. El-Lithy, Somaia I. Masoud

Publikováno v: Translational research : the journal of laboratory and clinical medicine. 177

Diabetic neuropathy (DN) is a common complication of diabetes mellitus that is hardly reversible at the late stages. Since treatment of neuropathic pain is predominantly symptomatic, a prophylactic measure would be useful. Both ibuprofen and L-argini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7e7aa3d100bb96f9b843017fa44493
https://pubmed.ncbi.nlm.nih.gov/27392937

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Ibuprofen suppresses depressive like behavior induced by BCG inoculation in mice: role of nitric oxide and prostaglandin

Autor: Nesreen H. El Gayar, May Hamza, Lobna A Saleh, Essam A. Nasr, Somaia I. Masoud, Abeer A. Abd El-Samad

Publikováno v: Pharmacology, biochemistry, and behavior. 125

Prostaglandins (PGs) and nitric oxide (NO) may be involved in the pathophysiology of depression. Since NSAIDs decrease PGs and NO production, they may have an antidepressant effect. The aim of the present work was to explore a possible antidepressant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::badd88fb7981ea7c0352862d6d1cd232
https://pubmed.ncbi.nlm.nih.gov/25101545

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