Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Soma Dhakal"'
Autor:
Aleah N. Edwards, Alexandria N. Iannucci, Jacob VanDenBerg, Annastiina Kesti, Tommie Rice, Srishty Sethi, Soma Dhakal, Philip M. Yangyuoru
Publikováno v:
ACS Omega, Vol 9, Iss 12, Pp 14343-14350 (2024)
Externí odkaz:
https://doaj.org/article/be739fc0eef540f9b3e8558bb4056d78
Publikováno v:
Nanomaterials, Vol 14, Iss 14, p 1185 (2024)
The use of DNA structures in creating multimodal logic gates bears high potential for building molecular devices and computation systems. However, due to the complex designs or complicated working principles, the implementation of DNA logic gates wit
Externí odkaz:
https://doaj.org/article/8ec744b27f374ecda3c2ccb1a956cc18
Publikováno v:
Biosensors, Vol 13, Iss 1, p 119 (2023)
The multiplexed detection of disease biomarkers is part of an ongoing effort toward improving the quality of diagnostic testing, reducing the cost of analysis, and accelerating the treatment processes. Although significant efforts have been made to d
Externí odkaz:
https://doaj.org/article/edf4ba2cb6fb49f68831516cbb11a878
Autor:
Zhao Zhao, Jinglin Fu, Soma Dhakal, Alexander Johnson-Buck, Minghui Liu, Ting Zhang, Neal W. Woodbury, Yan Liu, Nils G. Walter, Hao Yan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Cells compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here, the authors describe a self-assembly approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability, and observe an inversed correla
Externí odkaz:
https://doaj.org/article/0c8994d2379840b6bc7c9a797d47c2d7
Autor:
Kumar Sapkota, Soma Dhakal
Publikováno v:
Sensors, Vol 20, Iss 3, p 914 (2020)
Lysozyme is a conserved antimicrobial enzyme and has been cited for its role in immune modulation. Increase in lysozyme concentration in body fluids is also regarded as an early warning of some diseases such as Alzheimer’s, sarcoidosis, Crohn’s d
Externí odkaz:
https://doaj.org/article/a3c3f8b4f25346f0931f38a6b0dd9592
Publikováno v:
Sensors, Vol 19, Iss 16, p 3495 (2019)
Sensitive detection of nucleic acids and identification of single nucleotide polymorphism (SNP) is crucial in diagnosis of genetic diseases. Many strategies have been developed for detection and analysis of DNA, including fluorescence, electrical, op
Externí odkaz:
https://doaj.org/article/931e908e09c3410ebbc5a639ce0a4a7d
Publikováno v:
Methods and Protocols, Vol 1, Iss 4, p 40 (2018)
Prism-based total internal reflection fluorescence (pTIRF) microscopy is one of the most widely used techniques for the single molecule analysis of a vast range of samples including biomolecules, nanostructures, and cells, to name a few. It allows fo
Externí odkaz:
https://doaj.org/article/7fc812c1eab244cbad47f6dd9f058975
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e39271 (2012)
Enrichment of four tandem repeats of guanine (G) rich and cytosine (C) rich sequences in functionally important regions of human genome forebodes the biological implications of four-stranded DNA structures, such as G-quadruplex and i-motif, that can
Externí odkaz:
https://doaj.org/article/b14ed94a916641639ac9784683a56f14
Autor:
Roaa Mahmoud, Soma Dhakal
Publikováno v:
The Journal of Physical Chemistry B. 126:7252-7261
Branch migration (BM) of DNA Holliday junctions (HJs) occurs through base-pair rearrangements between homologous DNA molecules during the repair of double-strand breaks (DSBs) by homologous recombination. Despite the fact that BM is conserved among o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62fcc6a143bc5a73f0ab390889b495e8
https://doi.org/10.1021/acs.jpcb.2c03153
https://doi.org/10.1021/acs.jpcb.2c03153
Publikováno v:
Biophys J
The repair of double-stranded DNA breaks via homologous recombination involves a four-way cross-strand intermediate known as Holliday junction (HJ), which is recognized, processed, and resolved by a specific set of proteins. RuvA, a prokaryotic HJ-bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64a6a5d08502a2b1593de6abd7dead4e
https://doi.org/10.1016/j.bpj.2021.03.006
https://doi.org/10.1016/j.bpj.2021.03.006