Effect of national guidance on survival for babies born at 22 weeks’ gestation in England and Wales: population based cohort study

Autor: Bradley N Manktelow, Stavros Petrou, Jennifer J Kurinczuk, Richard Lindley, Victoria Nesbitt, Alan C Fenton, Sanjay Salgia, Sarah E Seaton, Matthew Babirecki, Anita Mittal, Ahmed Hassan, Karin Schwarz, Stephen Brearey, Mehdi Garbash, David Gibson, Pauline Adiotomre, Cath Seagrave, Hilary Dixon, Narendra Aladangady, Hassan Gaili, Matthew James, M Lal, Khalid Mannan, Dhaval Dave, Jennifer Birch, I Misra, Richard Nicholl, Charlotte Groves, Christos Zipitis, Joanne Fedee, Richa Gupta, Salim Yasin, Carrie Heal, Chris Knight, Hari Kumar, Delyth Webb, Sankara Narayanan, Elizabeth Eyre, Caroline Sullivan, Wynne Leith, Megan Eaton, Ambalika Das, Andrew Powls, Sanjeev Bali, Katharine Mcdevitt, Anna Gregory, Donovan Duffy, Shu-Ling Chuang, Lucy K Smith, Amit Gupta, Cheryl Battersby, Imran Ahmed, Chris Warren, Laura Stewart, Igor Fierens, Tristan Bate, Mark Johnson, Rashmi Gandhi, Nitin Goel, Artur Abelian, Shakir Saeed, Cheentan Singh, Hilary Conetta, Faith Emery, Vineet Gupta, Yee Aung, Vennila Ponnusamy, Pinki Surana, Caroline Delahunty, Anand Kamalanathan, Kavi Aucharaz, Matt Nash, Alex Allwood, Nigel Brooke, Jennifer Holman, Sobia Balal, Savi Sivashankar, Michael Grosdenier, Prakash Thiagarajan, Lidia Tyszcuzk, Bushra Abdul-Malik, Dominic Muogbo, Chrissie Oliver, Lucinda Winckworth, Naveen Athiraman, Jim Baird, Akinsola Ogundiya, Pamela Cairns, Porus Bastani, Giles Kendall, Puneet Nath, Yee Mon Aung, Ros Garr, Sundeep Sandhu, Anitha James, S Kinmond, Ruchika Gupta, Rebecca Winterson, Nick Barnes, AM Heuchan, Hannah Shore, Archana Mishra, DAMIEN ARMSTRONG, Oluseun Tayo, Carolina Zorro, J Coutts, Karen Turnock, David Deekollu, Victoria Sharp, Rajiv Chaudhary, Sam Wallis, Stan Craig, Lee Abbott, Shaveta Mulla, Penny Broggio, Peter McEwan, Divyen Shah, Grenville Fox, Alison Verner, Clare Cane, Clare Irving, Shelagh Parkinson, Ghada Ramadan, Ruth J Matthews, Ian Gallimore, Nigel Ruggins, Emily van Blankenstein, Penelope Young, Ramona Onita, Toria Klutse, Sonia Spathis, Sathish Krishnan, Samar Sen, Prem Pitchaikani, Jonathan Filkin, Ashok Karupaiah, Richard Heaver, Mohammad Alam, Patricia Cowley, Shilpa Ramesh, Julia Croft, Soma Sengupta, Anitha Vayalakkad, Arun Ramachandran, Se-Yeon Park, Bharath Gowda, Eleanor Bond, Daniel Dogar, Rebecca Kettle, Rathod Poorva, Maninder Bal, Mani Kandasamy, Claire Hollinsworh, Alaa Ghoneem, Girish Gowda, Abraham Isaac, Jo Behrsin, Ather Ahmed, Surendran Chandrasekaran, Tiziana Fragapane Muthukumar, Bivan Saha, Sangeeta Tiwary, Dush Batra, Sanath Reddy, Aesha Mohammedi, Salamatu Jalloh, Kemy Naidoo, Anjali Pektar, Adedayo Owoeye, Umapathee Majuran, Helen Purves, Esther Morris, Peter Curtis, Tayyaba Aamir, Angela Yannoulias, Edward Yates, Abijeet Godhamgaonkar, Abby Parish, Mario Martínez-Jiménez, LM Wong, Dr Morris, Dr Siramhatia, Nim Subhedar, Jo MacLeod, Arin Mukherjee, Dr Bird, Saulius Satas, Andrew Eccleston, Dominic O'Reilly, Dr Bhushan, P Van Der Heide, Helen Rhodes Ben Stenson, Ambrose Onibere, Nita Saxena

Publikováno v: BMJ Medicine, Vol 2, Iss 1 (2023)

Objectives To explore the effect of changes in national clinical recommendations in 2019 that extended provision of survival focused care to babies born at 22 weeks’ gestation in England and Wales.Design Population based cohort study.Setting Englan

Externí odkaz: https://doaj.org/article/4280309e7532482487fea1dbe4046d40

Final Report on Clinical Outcomes and Tumor Recurrence Patterns of a Pilot Study Assessing Efficacy of Belinostat (PXD-101) with Chemoradiation for Newly Diagnosed Glioblastoma

Autor: Karen Xu, Karthik Ramesh, Vicki Huang, Saumya S. Gurbani, James Scott Cordova, Eduard Schreibmann, Brent D. Weinberg, Soma Sengupta, Alfredo D. Voloschin, Matthias Holdhoff, Peter B. Barker, Lawrence R. Kleinberg, Jeffrey J. Olson, Hui-Kuo G. Shu, Hyunsuk Shim

Publikováno v: Tomography, Vol 8, Iss 2, Pp 688-700 (2022)

Glioblastoma (GBM) is highly aggressive and has a poor prognosis. Belinostat is a histone deacetylase inhibitor with blood–brain barrier permeability, anti-GBM activity, and the potential to enhance chemoradiation. The purpose of this clinical tria

Externí odkaz: https://doaj.org/article/c5d64c1e66924dba9ace3ae3ee5433e3

Ligand-Gated Ion Channels as Targets for Treatment and Management of Cancers

Autor: Rohan Rao, Sanjit Shah, Debanjan Bhattacharya, Donatien Kamdem Toukam, Román Cáceres, Daniel A. Pomeranz Krummel, Soma Sengupta

Publikováno v: Frontiers in Physiology, Vol 13 (2022)

Ligand-gated ion channels are an ionotropic receptor subtype characterized by the binding of an extracellular ligand, followed by the transient passage of ions through a transmembrane pore. Ligand-gated ion channels are commonly subcategorized into t

Externí odkaz: https://doaj.org/article/4440816b4f0f485581f61b6b855aa0ba

An interactive single cell web portal identifies gene and cell networks in COVID-19 host responses

Autor: Kang Jin, Eric E. Bardes, Alexis Mitelpunkt, Jake Y. Wang, Surbhi Bhatnagar, Soma Sengupta, Daniel Pomeranz Krummel, Marc E. Rothenberg, Bruce J. Aronow

Publikováno v: iScience, Vol 24, Iss 10, Pp 103115- (2021)

Summary: Numerous studies have provided single-cell transcriptome profiles of host responses to SARS-CoV-2 infection. Critically lacking however is a data mine that allows users to compare and explore cell profiles to gain insights and develop new hy

Externí odkaz: https://doaj.org/article/02a5c99eec9b4449b05e89883b6bdcbf

COVID-19 Vaccine Mandates for Healthcare Professionals in the United States

Autor: Rohan Rao, Abigail Koehler, Katrina Beckett, Soma Sengupta

Publikováno v: Vaccines, Vol 10, Iss 9, p 1425 (2022)

Healthcare workers (HCWs) need to be vaccinated against COVID-19 because they care for vulnerable patients. Hesitation to receiving the COVID-19 vaccine stems from the argument of bodily autonomy, novel mRNA vaccine technology, and conspiracy theorie

Externí odkaz: https://doaj.org/article/6486c0e1a4a443dd822b52a155af65ac