Improved dissolution and micromeritic properties of naproxen from spherical agglomerates: preparation, in vitro and in vivo characterization

Autor: Damineni Saritha, Penjuri Subhash Chandra Bose, Poreddy Srikanth Reddy, Grandhi Madhuri, Ravouru Nagaraju

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 48, Iss 4, Pp 683-690 (2012)

Naproxen, an anti-inflammatory drug, exhibits poor aqueous solubility, which limits the pharmacological effects. The present work was carried out to study the effect of agglomeration on micromeritic properties and dissolution. Naproxen agglomerates w

Externí odkaz: https://doaj.org/article/4631506b44ae4ff790546ce210c87ac1

Residual solvent determination by head space gas chromatography with flame ionization detector in omeprazole API

Autor: Preeti Pandey, Saurabh Pandey, Raj Kumar, Narendra Pal Singh

Publikováno v: Brazilian Journal of Pharmaceutical Sciences, Vol 47, Iss 2, Pp 379-384 (2011)
Brazilian Journal of Pharmaceutical Sciences, Volume: 47, Issue: 2, Pages: 379-384, Published: JUN 2011
Brazilian Journal of Pharmaceutical Sciences; Vol. 47 No. 2 (2011); 379-384
Brazilian Journal of Pharmaceutical Sciences; Vol. 47 Núm. 2 (2011); 379-384
Brazilian Journal of Pharmaceutical Sciences; v. 47 n. 2 (2011); 379-384
Brazilian Journal of Pharmaceutical Sciences
Universidade de São Paulo (USP)
instacron:USP

Residual solvents in pharmaceutical samples are monitored using gas chromatography with head space. Based on good manufacturing practices, measuring residual solvents is mandatory for the release testing of all active pharmaceutical ingredients (API)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26abd44d766d3c51eb162d9d93926dc5
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502011000200019