Zobrazeno 1 - 10
of 1 483
pro vyhledávání: '"Solvent accessibility"'
Publikováno v:
J, Vol 6, Iss 2, Pp 236-247 (2023)
The COVID-19 pandemic, caused by the coronavirus SARS-CoV-2, has generated a renewed interest in the larger family of Coronaviridae, which causes a variety of different respiratory infections in a variety of different hosts. Understanding the mechani
Externí odkaz:
https://doaj.org/article/77d7f5c1dc51458dbb7f1c3985e208eb
Publikováno v:
RNA Biology, Vol 19, Iss 1, Pp 1179-1189 (2022)
Given the challenges for the experimental determination of RNA tertiary structures, probing solvent accessibility has become increasingly important to gain functional insights. Among various chemical probes developed, backbone-cleaving hydroxyl radic
Externí odkaz:
https://doaj.org/article/b23849d85bb84800bcd36b83e2a4e985
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 2223-2234 (2022)
Sequence-based predictors of the residue-level protein function and structure cover a broad spectrum of characteristics including intrinsic disorder, secondary structure, solvent accessibility and binding to nucleic acids. They were catalogued and ev
Externí odkaz:
https://doaj.org/article/1f4a5fdf26984052852ae2a58c5b0ab0
Autor:
Matthias Niemann, Yara Strehler, Nils Lachmann, Fabian Halleck, Klemens Budde, Gideon Hönger, Stefan Schaub, Benedict M. Matern, Eric Spierings
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Development of donor-specific human leukocyte antigen (HLA) antibodies (DSA) remains a major risk factor for graft loss following organ transplantation, where DSA are directed towards patches on the three-dimensional structure of the respective organ
Externí odkaz:
https://doaj.org/article/bbd636c2afcf480f920489f8af6db569
Autor:
Akanksha Pandey, Edward L. Braun
Publikováno v:
Biophysica, Vol 1, Iss 2, Pp 87-105 (2021)
Despite the long history of using protein sequences to infer the tree of life, the potential for different parts of protein structures to retain historical signal remains unclear. We propose that it might be possible to improve analyses of phylogenom
Externí odkaz:
https://doaj.org/article/b9cd172b4a534695b75ee72413abcbad
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5791-5799 (2021)
Protein–solvent interaction provides important features for protein surface engineering when the structure is absent or partially solved. Presently, we can integrate the notion of solvent exposed/buried residues with that of their flexibility and i
Externí odkaz:
https://doaj.org/article/f6a1c988c0cb4d7481cf93a7c7fbc45b
Akademický článek
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Publikováno v:
IEEE Access, Vol 7, Pp 30042-30049 (2019)
The study of nucleic acid-binding protein (NBP) has important significance for us to understand critical intracellular activities, such as the transmission of cellular genetic information, cell metabolism, substance transport, and signal transduction
Externí odkaz:
https://doaj.org/article/5b13ec8c1423457e8b653809c48ae395
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2021)
Solvent accessibility (SASA) is a key feature of proteins for determining their folding and stability. SASA is computed from protein structures with different algorithms, and from protein sequences with machine-learning based approaches trained on so
Externí odkaz:
https://doaj.org/article/ebcb82afa0154b0298885869984d197a
Autor:
Simone Marini, Marco Oliva, Ilya B. Slizovskiy, Noelle Robertson Noyes, Christina Boucher, Mattia Prosperi
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Antimicrobial resistance (AMR) is a significant and growing public health threat. Sequencing of bacterial isolates is becoming more common, and therefore automatic identification of resistant bacterial strains is of pivotal importance for efficient,
Externí odkaz:
https://doaj.org/article/3ab13cef5923467c9e71e213f63cbdad