Výsledky vyhledávání - "Solveig Boehnke"

Carbaboranes – more than just phenyl mimetics

Autor: Sven Hofmann, Annette G. Beck-Sickinger, Ágota Bartók, Solveig Boehnke, Stefan Saretz, Evamarie Hey-Hawkins, René Frank, Menyhárt B. Sárosi, Verena M. Ahrens, Martin Kellert, Souvik Pandey

Publikováno v: Pure and Applied Chemistry. 87:163-171

Dicarba-closo-dodecaboranes(12) (C2B10H12, carbaboranes) are highly hydrophobic and stable icosahedral carbon-containing boron clusters. The cage framework of these clusters can be modified with a variety of substituents, both at the carbon and at th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1d0b0b4328c3e7ee14db51213542bdef
https://doi.org/10.1515/pac-2014-1006

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Imitation and modification of bioactive lead structures via integration of boron clusters

Autor: Solveig Boehnke, René Frank, Annette G. Beck-Sickinger, Verena M. Ahrens, Evamarie Hey-Hawkins, Matthias Scholz, Sven Stadlbauer

Publikováno v: Pure and Applied Chemistry. 84:2289-2298

In medicinal chemistry, carbaboranes can be employed either as boron carriers for boron neutron capture therapy (BNCT) or as scaffolds for radiodiagnostic or therapeutic agents. We have developed a suitable synthesis employing the phosphoramidite met

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3b2bc73e97bbf2e6e34df9d24bfd0f05
https://doi.org/10.1351/pac-con-11-11-02

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From ortho-carbaborane-9-thiol towards new building blocks

Autor: Almaz Aliev, René Frank, Solveig Boehnke, Evamarie Hey-Hawkins

Publikováno v: Polyhedron. 39:9-13

The potential of 1,2-dicarba-closo-dodecaborane(12)-9-thiol, 9-HS-1,2-closo-C2B10H11, for the design of novel building blocks is highlighted by two examples envisioned for incorporation into tumor-selective peptides for boron neutron capture therapy

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ffc7b4ceea014a0dd2c615a1cb0f605
https://doi.org/10.1016/j.poly.2012.03.003

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A mechanistic investigation of cell-penetrating Tat peptides with supported lipid membranes

Autor: Leone Spiccia, Stefania Piantavigna, Lisandra L. Martin, Bim Graham, George A. McCubbin, Solveig Boehnke

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1808(7):1811-1817

The multifarious Tat peptide derived from the HIV-1 virus exhibits antimicrobial activity. In this article, we use Quartz Crystal Microbalance with Dissipation monitoring (QCM-D) to investigate the mechanisms of action of Tat (44–57) and Tat (49–

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ee58ac6ad1a5d1a780a59f899c7b1b4

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Receptor-mediated uptake of boron-rich neuropeptide y analogues for boron neutron capture therapy

Autor: Dorothee Iffland, Solveig Boehnke, C. Schütz, Verena M. Ahrens, G. Hampel, René Frank, Nicolas H. Bings, Evamarie Hey-Hawkins, Annette G. Beck-Sickinger

Publikováno v: ChemMedChem. 10(1)

Peptidic ligands selectively targeting distinct G protein-coupled receptors that are highly expressed in tumor tissue represent a promising approach in drug delivery. Receptor-preferring analogues of neuropeptide Y (NPY) bind and activate the human Y

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be052a4aa8847b4620747e5397d12c6d
https://pubmed.ncbi.nlm.nih.gov/25338544

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