Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Soluble immune checkpoints"'
Autor:
Joao Gorgulho, Sven H. Loosen, Ramsha Masood, Franziska Giehren, Francesca Pagani, Gustav Buescher, Lorenz Kocheise, Vincent Joerg, Constantin Schmidt, Kornelius Schulze, Christoph Roderburg, Eva Kinkel, Britta Fritzsche, Simon Wehmeyer, Benjamin Schmidt, Paul Kachel, Christina Rolling, Julian Götze, Alina Busch, Marianne Sinn, Thais Pereira-Veiga, Harriet Wikman, Maria Geffken, Sven Peine, Urte Matschl, Markus Altfeld, Samuel Huber, Ansgar W. Lohse, Fabian Beier, Tim H. Brümmendorf, Carsten Bokemeyer, Tom Luedde, Johann von Felden
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-15 (2024)
Abstract Background The major breakthrough in cancer therapy with immune checkpoint inhibitors (ICIs) has highlighted the important role of immune checkpoints in antitumoral immunity. However, most patients do not achieve durable responses, making bi
Externí odkaz:
https://doaj.org/article/c2fb5d5ae25641debf5ff764186a0fca
Autor:
Xingcheng Yang, Lijun Jiang, Xiaoying Zhang, Juan Peng, Hu Qian, Lifang Huang, Shaolong He, Zhiqiong Wang, Liting Chen, Yicheng Zhang, Ling Ma, Yuan Chen, Jia Wei
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-5 (2024)
Abstract The role of the compromised immune microenvironment, including immune checkpoints, in myelodysplastic syndromes (MDS) has been identified as critical This study aimed to investigate the expression patterns of immune checkpoints, particularly
Externí odkaz:
https://doaj.org/article/0c0886bf71d24e7fb1a80567baeefd78
Autor:
Tudorita Gabriela Paranga, Mariana Pavel-Tanasa, Daniela Constantinescu, Elena Iftimi, Claudia Elena Plesca, Ionela-Larisa Miftode, Petru Cianga, Egidia Miftode
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionOver the past four years, the COVID-19 pandemic has posed serious global health challenges. The severe form of disease and death resulted from the failure of immune regulatory mechanisms, closely highlighted by the dual proinflammatory cy
Externí odkaz:
https://doaj.org/article/3909a79faa574a94b5eddf88dda47aa8
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-32 (2024)
Abstract Longitudinal sampling of tumor tissue from patients with solid cancers, aside from melanoma and a few other cases, is often unfeasible, and thus may not capture the plasticity of interactions between the tumor and immune system under selecti
Externí odkaz:
https://doaj.org/article/9a7a67bd92584ad988f0fb41a0f405ba
Autor:
Shima Shahbaz, Najmeh Bozorgmehr, Julia Lu, Mohammed Osman, Wendy Sligl, D. Lorne Tyrrell, Shokrollah Elahi
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 5 (2023)
ABSTRACT There is an urgent need to better understand the impact of different severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants on immune response and disease dynamics to facilitate better intervention strategies. Here, we show th
Externí odkaz:
https://doaj.org/article/ea83091d2101436b9e2f6bb708d6f972
Autor:
Silvia Mezi, Giulia Pomati, Giulia Fiscon, Sasan Amirhassankhani, Ilaria Grazia Zizzari, Chiara Napoletano, Aurelia Rughetti, Ernesto Rossi, Giovanni Schinzari, Giampaolo Tortora, Gaetano Lanzetta, Giulia D’Amati, Marianna Nuti, Daniele Santini, Andrea Botticelli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe immune profile of each patient could be considered as a portrait of the fitness of his/her own immune system. The predictive role of the immune profile in immune-related toxicities (irAEs) development and tumour response to treatment wa
Externí odkaz:
https://doaj.org/article/dc54455f60d4429eb31fa7aa6fc746c3
Autor:
Mohammad Sadegh Soltani-Zangbar, Forough Parhizkar, Mojtaba Abdollahi, Navid Shomali, Leili Aghebati-Maleki, Sima Shahmohammadi Farid, Leila Roshangar, Ata Mahmoodpoor, Mehdi Yousefi
Publikováno v:
Cell Communication and Signaling, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract During SARS-CoV-2 infection, an effective immune response provides the first line of defense; however, excessive inflammatory innate immunity and impaired adaptive immunity may harm tissues. Soluble immune mediators are involved in the dynam
Externí odkaz:
https://doaj.org/article/2eef3eecbed7491ea6632fe8f044ae21
Akademický článek
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Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Alicia Landeira-Viñuela, Carlota Arias-Hidalgo, Pablo Juanes-Velasco, Miguel Alcoceba, Almudena Navarro-Bailón, Carlos Eduardo Pedreira, Quentin Lecrevisse, Laura Díaz-Muñoz, José Manuel Sánchez-Santos, Ángela-Patricia Hernández, Marina L. García-Vaquero, Rafael Góngora, Javier De Las Rivas, Marcos González, Alberto Orfao, Manuel Fuentes
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Chronic lymphocytic leukemia (CLL) is a lymphoid neoplasm characterized by the accumulation of mature B cells. The diagnosis is established by the detection of monoclonal B lymphocytes in peripheral blood, even in early stages [monoclonal B-cell lymp
Externí odkaz:
https://doaj.org/article/62d0774abeb14b328f36f357e45ac731