356 - Novel approach for depletion of TCRab+ and CD45RA+ cells from apheresis products products using the CliniMACS Prodigy

Autor: Soltenborn, S., Stenzel, J.J., Thießen, C., Hebbeker, F., Kauling, B., Meißner, R., Kaltz, N., Langeveld, K., Malchow, M., Assenmacher, M., Huppert, V., Dzionek, J.

Publikováno v: In Cytotherapy May 2018 20(5) Supplement:S119-S119

Optimization of Human NK Cell Manufacturing: Fully Automated Separation, Improved Ex Vivo Expansion Using IL-21 with Autologous Feeder Cells, and Generation of Anti-CD123-CAR-Expressing Effector Cells.

Autor: Klöß S; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany., Oberschmidt O; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany., Morgan M; 2 Institute of Experimental Hematology, Hannover Medical School , Hannover, Germany.; 3 REBIRTH Cluster of Excellence, Hannover Medical School , Hannover, Germany., Dahlke J; 2 Institute of Experimental Hematology, Hannover Medical School , Hannover, Germany.; 3 REBIRTH Cluster of Excellence, Hannover Medical School , Hannover, Germany., Arseniev L; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany., Huppert V; 4 Miltenyi Biotec GmbH, Bergisch Gladbach , Germany., Granzin M; 4 Miltenyi Biotec GmbH, Bergisch Gladbach , Germany., Gardlowski T; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany., Matthies N; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany., Soltenborn S; 4 Miltenyi Biotec GmbH, Bergisch Gladbach , Germany., Schambach A; 2 Institute of Experimental Hematology, Hannover Medical School , Hannover, Germany.; 3 REBIRTH Cluster of Excellence, Hannover Medical School , Hannover, Germany.; 5 Division of Hematology/Oncology, Boston Children's Hospital, Harvard Medical School , Boston, Massachusetts., Koehl U; 1 Institute for Cellular Therapeutics, GMPDU, IFB-Tx, Hannover Medical School , Hannover, Germany.

Publikováno v: Human gene therapy [Hum Gene Ther] 2017 Oct; Vol. 28 (10), pp. 897-913. Date of Electronic Publication: 2017 Aug 15.

Next-Generation CEA-CAR-NK-92 Cells against Solid Tumors: Overcoming Tumor Microenvironment Challenges in Colorectal Cancer.

Autor: Franzén, Alexander Sebastian^1,2 (AUTHOR), Boulifa, Abdelhadi^1,2 (AUTHOR), Radecke, Clarissa² (AUTHOR), Stintzing, Sebastian² (AUTHOR), Raftery, Martin J.^1,2 (AUTHOR), Pecher, Gabriele^1,2 (AUTHOR) gabriele.pecher@charite.de

Publikováno v: Cancers. Jan2024, Vol. 16 Issue 2, p388. 20p.

Fully automated expansion and activation of clinical-grade natural killer cells for adoptive immunotherapy.

Autor: Granzin M; Miltenyi Biotec GmbH, Bergisch Gladbach, Germany; Innate Immunity Group, German Cancer Research Center, Heidelberg, Germany. Electronic address: markusgr@miltenyibiotec.de., Soltenborn S; Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Müller S; Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Kollet J; Miltenyi Biotec GmbH, Bergisch Gladbach, Germany., Berg M; National Heart, Lung and Blood Institute, Hematology Branch, Bethesda, Maryland, USA., Cerwenka A; Innate Immunity Group, German Cancer Research Center, Heidelberg, Germany., Childs RW; National Heart, Lung and Blood Institute, Hematology Branch, Bethesda, Maryland, USA., Huppert V; Miltenyi Biotec GmbH, Bergisch Gladbach, Germany. Electronic address: volker@miltenyibiotec.de.

Publikováno v: Cytotherapy [Cytotherapy] 2015 May; Vol. 17 (5), pp. 621-32.

Emerging Targeted Therapies for HER2-Positive Breast Cancer.

Autor: Mercogliano, María Florencia¹ (AUTHOR) fmercogliano@dna.uba.ar, Bruni, Sofía¹ (AUTHOR), Mauro, Florencia Luciana¹ (AUTHOR), Schillaci, Roxana¹ (AUTHOR) fmercogliano@dna.uba.ar

Publikováno v: Cancers. Apr2023, Vol. 15 Issue 7, p1987. 50p.