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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor.

Autor: Freeman-Cook K; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Hoffman RL; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Miller N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Almaden J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Chionis J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Zhang Q; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Eisele K; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Liu C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Zhang C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Huser N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Nguyen L; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Costa-Jones C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Niessen S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Carelli J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Lapek J; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Weinrich SL; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Wei P; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., McMillan E; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Wilson E; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Wang TS; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., McTigue M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Ferre RA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., He YA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Ninkovic S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Behenna D; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Tran KT; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Sutton S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Nagata A; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Ornelas MA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Kephart SE; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Zehnder LR; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Murray B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Xu M; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Solowiej JE; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Visswanathan R; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Boras B; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Looper D; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Lee N; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Bienkowska JR; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Zhu Z; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Kan Z; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Ding Y; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Mu XJ; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Oderup C; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., Salek-Ardakani S; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., White MA; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA., VanArsdale T; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA. Electronic address: todd.vanarsdale@pfizer.com., Dann SG; Pfizer Global Research and Development La Jolla, 10770 Science Center Drive, San Diego, CA 92121, USA. Electronic address: stephen@genesistherapeutics.ai.

Publikováno v: Cancer cell [Cancer Cell] 2021 Oct 11; Vol. 39 (10), pp. 1404-1421.e11. Date of Electronic Publication: 2021 Sep 13.