Microbeam Irradiation as a Simultaneously Integrated Boost in a Conventional Whole-Brain Radiotherapy Protocol

Autor: Jaekel, Felix, Bräuer-Krisch, Elke, Bartzsch, Stefan, Laissue, Jean, Blattmann, Hans, Scholz, Marten, Soloviova, Julia, Hildebrandt, Guido, Schültke, Elisabeth

Microbeam radiotherapy (MRT), an experimental high-dose rate concept with spatial fractionation at the micrometre range, has shown a high therapeutic potential as well as good preservation of normal tissue function in pre-clinical studies. We investi

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Microbeam Irradiation as a Simultaneously Integrated Boost in a Conventional Whole-Brain Radiotherapy Protocol.

Autor: Jaekel F; Department of Radiooncology, Rostock University Medical Center, 18059 Rostock, Germany., Bräuer-Krisch E; Biomedical Beamline ID 17, European Synchrotron Radiation Facility (ESRF), 38043 Grenoble, France., Bartzsch S; Department of Radiooncology, Technical University of Munich, 81675 Munich, Germany.; Institute for Radiation Medicine, Helmholtz Center Munich, 85764 Munich, Germany., Laissue J; Institute of Anatomy, University of Bern, 3012 Bern, Switzerland., Blattmann H; Niederwiesstr 13C, 5417 Untersiggenthal, Switzerland., Scholz M; Department of Radiooncology, Rostock University Medical Center, 18059 Rostock, Germany., Soloviova J; Department of Radiooncology, Rostock University Medical Center, 18059 Rostock, Germany.; Department of Paediatric Surgery, Leipzig University Medical Centre, 04103 Leipzig, Germany., Hildebrandt G; Department of Radiooncology, Rostock University Medical Center, 18059 Rostock, Germany., Schültke E; Department of Radiooncology, Rostock University Medical Center, 18059 Rostock, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Jul 28; Vol. 23 (15). Date of Electronic Publication: 2022 Jul 28.