Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Solomon Mwaigwisya"'
Autor:
Camilla L.C. Ip, Matthew Loose, John R. Tyson, Mariateresa de Cesare, Bonnie L. Brown, Miten Jain, Richard M. Leggett, David A. Eccles, Vadim Zalunin, John M. Urban, Paolo Piazza, Rory J. Bowden, Benedict Paten, Solomon Mwaigwisya, Elizabeth M. Batty, Jared T. Simpson, Terrance P. Snutch, Ewan Birney, David Buck, Sara Goodwin, Hans J. Jansen, Justin O'Grady, Hugh E. Olsen, MinION Analysis and Reference Consortium
Publikováno v:
F1000Research, Vol 4 (2015)
The advent of a miniaturized DNA sequencing device with a high-throughput contextual sequencing capability embodies the next generation of large scale sequencing tools. The MinION™ Access Programme (MAP) was initiated by Oxford Nanopore Technologie
Externí odkaz:
https://doaj.org/article/b9fd4c6fe9d440deaa166902e0f8d188
Autor:
Stellah G. Mpagama, Charles Mtabho, Solomon Mwaigwisya, Liberate J. Mleoh, I Marion Sumari-de Boer, Scott K. Heysell, Eric R. Houpt, Gibson S. Kibiki
Publikováno v:
Tuberculosis Research and Treatment, Vol 2012 (2012)
In Tanzania sputum culture for tuberculosis (TB) is resource intensive and available only at zonal facilities. In this study overnight pooled sputum collection technique was compared with standard spot morning collection among pulmonary TB suspects a
Externí odkaz:
https://doaj.org/article/1b90115440a2419e85bf9358e5f428cb
Autor:
John Wain, Wolfgang Rabsch, Justin O'Grady, Timothy J. Dallman, Salvatore Rubino, Philip Ashton, Satheesh Nair, Solomon Mwaigwisya
Publikováno v:
Nature Biotechnology. 33:296-300
Short-read, high-throughput sequencing technology cannot identify the chromosomal position of repetitive insertion sequences that typically flank horizontally acquired genes such as bacterial virulence genes and antibiotic resistance genes. The MinIO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac43005a992a44428fada3373db23b30
https://doi.org/10.1038/nbt.3103
https://doi.org/10.1038/nbt.3103
Autor:
Solomon Mwaigwisya, Cléo T. G. V. M. T. Pires, K. Schmidt, Nigel J. Saunders, D. Munroe, Justin O'Grady, Lisa Crossman, John Wain, Neil Woodford, Michel Doumith, Arshad Khan, David M. Livermore
Publikováno v:
Europe PubMed Central
Objectives: The introduction of metagenomic sequencing to diagnostic microbiology has been hampered by slowness, cost and complexity. We explored whether MinION nanopore sequencing could accelerate diagnosis and resistance profiling, using complicate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bc65adf4f9f9cae3ddd8c5b2ab95f62
https://bura.brunel.ac.uk/handle/2438/19914
https://bura.brunel.ac.uk/handle/2438/19914
Autor:
Gemma C. Langridge, Elizabeth de Pinna, Gauri Godbole, Philip Ashton, Satheesh Nair, Martin Day, Solomon Mwaigwisya, Steve Connell, Anaïs Painset, Michel Doumith
Publikováno v:
The Journal of antimicrobial chemotherapy. 71(12)
Objectives: WGS and phenotypic methods were used to determine the prevalence of azithromycin resistance in Salmonella enterica isolates from the UK and to identify the underlying mechanisms of resistance. Methods: WGS by Illumina HiSeq was carried ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8c29b364c44d063353a928cf57a7d95
https://pubmed.ncbi.nlm.nih.gov/27585964
https://pubmed.ncbi.nlm.nih.gov/27585964
Autor:
Gibson S. Kibiki, Jean Gratz, Solomon Mwaigwisya, Suporn Pholwat, Eric R. Houpt, Stellah G. Mpagama, Charles M. Mtabho, Rob E. Aarnoutse, Norah Ndusilo, Scott K. Heysell
Publikováno v:
Antimicrobial Agents and Chemotherapy, 55, 12, pp. 5819-25
Antimicrobial Agents and Chemotherapy, 55, 5819-25
Antimicrobial Agents and Chemotherapy, 55, 5819-25
Low antituberculosis (TB) drug levels are common, but their clinical significance remains unclear, and methods of measurement are resource intensive. Subjects initiating treatment for sputum smear-positive pulmonary TB were enrolled from Kibong'oto N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b890d56897c70d6cb6e216825e9e26b
https://doi.org/10.1128/aac.05561-11
https://doi.org/10.1128/aac.05561-11
Low rate of fluoroquinolone resistance in Mycobacterium tuberculosis isolates from northern Tanzania
Autor:
Hadija H. Semvua, Tridia van der Laan, Solomon Mwaigwisya, Jakko van Ingen, Gibson S. Kibiki, Jossy van den Boogaard, Martin J. Boeree, Dick van Soolingen, Rob E. Aarnoutse
Publikováno v:
Journal of Antimicrobial Chemotherapy, 66, 8, pp. 1810-4
Journal of Antimicrobial Chemotherapy, 66, 1810-4
Journal of Antimicrobial Chemotherapy, 66, 1810-4
Item does not contain fulltext OBJECTIVES: Fluoroquinolones are used in second-line treatment of tuberculosis (TB) and have a potential role in shortening TB treatment duration. The wide use of fluoroquinolones in the treatment of other infections, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a36e956f20198dd8254b3d41073fe7a
https://doi.org/10.1093/jac/dkr205
https://doi.org/10.1093/jac/dkr205
Publikováno v:
Expert review of molecular diagnostics. 15(5)
Bloodstream infection (BSI) by microorganisms can lead to sepsis. This condition has a high mortality rate, which rises significantly with delays in initiation of appropriate antimicrobial treatment. Current culture methods for diagnosing BSI have lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24a8ef8fc60323eb9c6112ad03420489
https://pubmed.ncbi.nlm.nih.gov/25866124
https://pubmed.ncbi.nlm.nih.gov/25866124
Autor:
Josephine M, Bryant, Simon R, Harris, Julian, Parkhill, Rodney, Dawson, Andreas H, Diacon, Paul, van Helden, Alex, Pym, Aziah A, Mahayiddin, Charoen, Chuchottaworn, Ian M, Sanne, Cheryl, Louw, Martin J, Boeree, Michael, Hoelscher, Timothy D, McHugh, Anna L C, Bateson, Robert D, Hunt, Solomon, Mwaigwisya, Laura, Wright, Stephen H, Gillespie, Stephen D, Bentley
Publikováno v:
The Lancet. Respiratory medicine. 1(10)
Recurrence of tuberculosis after treatment makes management difficult and is a key factor for determining treatment efficacy. Two processes can cause recurrence: relapse of the primary infection or re-infection with an exogenous strain. Although re-i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::97d51fc470c13a9b57565cf538736b55
https://pubmed.ncbi.nlm.nih.gov/24461746
https://pubmed.ncbi.nlm.nih.gov/24461746
Autor:
Antima Gupta, Simon Gibbons, John P. Malkinson, Dimitrios Evangelopoulos, Barbara Saxty, Juan D. Guzman, Timothy D. McHugh, Sanjib Bhakta, Solomon Mwaigwisya, Kristian Birchall
Publikováno v:
BMJ Open
Objectives: Lead antituberculosis (anti-TB) molecules with novel mechanisms of action are urgently required to fuel the anti-TB drug discovery pipeline. The aim of this study was to validate the use of the high-throughput spot culture growth inhibiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9190f505a3c97c41f6cb744dd592045a
http://europepmc.org/articles/PMC3693423
http://europepmc.org/articles/PMC3693423