O23: Comparison of polygenic risk score in patients with early-onset vs late-onset dementia and the contribution of rare genetic variation*

Autor: Wright, Carter, Cooper, Sara, Cochran, Nicholas, Cochran, Meagan, Moyers, Belle, Roberson, Erik, Lawlor, James, Myers, Richard, Taylor, Jared, Solomon, Veronika, Geldmacher, David, Love, Marissa Natelson

Publikováno v: In Genetics in Medicine Open 2023 1(1) Supplement

Contributions of rare and common variation to early-onset and atypical dementia risk.

Autor: Wright CA; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.; University of Alabama in Huntsville, Huntsville, Alabama 35899, USA., Taylor JW; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Cochran M; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Lawlor JMJ; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Moyers BA; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Amaral MD; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Bonnstetter ZT; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Carter P; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Solomon V; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Myers RM; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Love MN; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Geldmacher DS; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Cooper SJ; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA., Roberson ED; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA., Cochran JN; HudsonAlpha Institute for Biotechnology, Huntsville, Alabama 35806, USA.; Alzheimer's Disease Center, Department of Neurology, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Feb 08. Date of Electronic Publication: 2023 Feb 08.