Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Solmaz, Sobhanifar"'
Autor:
J. Andrew N. Alexander, Liam J. Worrall, Jinhong Hu, Marija Vuckovic, Nidhi Satishkumar, Raymond Poon, Solmaz Sobhanifar, Federico I. Rosell, Joshua Jenkins, Daniel Chiang, Wesley A. Mosimann, Henry F. Chambers, Mark Paetzel, Som S. Chatterjee, Natalie C. J. Strynadka
Publikováno v:
Nature. 613:375-382
Broad-spectrum β-lactam antibiotic resistance in Staphylococcus aureus is a global healthcare burden1,2. In clinical strains, resistance is largely controlled by BlaR13, a receptor that senses β-lactams through the acylation of its sensor domain, i
Autor:
J Andrew N, Alexander, Liam J, Worrall, Jinhong, Hu, Marija, Vuckovic, Nidhi, Satishkumar, Raymond, Poon, Solmaz, Sobhanifar, Federico I, Rosell, Joshua, Jenkins, Daniel, Chiang, Wesley A, Mosimann, Henry F, Chambers, Mark, Paetzel, Som S, Chatterjee, Natalie C J, Strynadka
Publikováno v:
Nature.
Broad-spectrum β-lactam antibiotic resistance in Staphylococcus aureus is a global healthcare burden
Autor:
Solmaz Sobhanifar, Liam J Worrall, Dustin T King, Gregory A Wasney, Lars Baumann, Robert T Gale, Michael Nosella, Eric D Brown, Stephen G Withers, Natalie C J Strynadka
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006067 (2016)
In recent years, there has been a growing interest in teichoic acids as targets for antibiotic drug design against major clinical pathogens such as Staphylococcus aureus, reflecting the disquieting increase in antibiotic resistance and the historical
Externí odkaz:
https://doaj.org/article/5145b8a01c064e478e04e7f807981379
Autor:
Krithika Muthuraman, Richard E. Higgs, Carl L. Hansen, Maren de Vries, Mark J. Mulligan, Kizzmekia S. Corbett, Ping Xiang, Nicole V. Johnson, Jory A. Goldsmith, Jason S. McLellan, John R. Mascola, Marissa H. Piper, Lucas Kraft, Jamie L. Blackbourne, Samuel J. Hinshaw, Davide Pellacani, Stefanie Žentelis, Christopher M. Wiethoff, Solmaz Sobhanifar, David R. Martinez, Franz J. Triana, Thomas P. Cujec, Barney S. Graham, Robert W. Cross, Ching-Lin Hsieh, Beverly A. Heinz, Denisa Foster, Ralph S. Baric, Sean A. Tycho, Jorg Hendle, David Collins, Eun Sung Yang, Ester Falconer, Daniel Wrapp, Andrew C. Adams, Roza Bidshahri, A. Pustilnik, Yuri Hwang, Adil Mohamed, Julian Davies, Yi Zhang, Patricia Brown-Augsburger, Bryan Edward Jones, Shawn J. Berens, Kevin R. Jepson, Bryan C. Barnhart, Kathryn Westendorf, Lingshu Wang, Viktoriya Borisevich, Meike Dittmann, Maia A. Smith, Deepa Balasubramaniam, Thomas W. Geisbert, Rodrigo Goya, Hayley M. Belli, Olubukola M. Abiona, Marie I. Samanovic
Publikováno v:
bioRxiv
Science Translational Medicine
Science Translational Medicine
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) poses a public health threat for which preventive and therapeutic agents are urgently needed. Neutralizing antibodies are a key class of therapeutics that may bridge widespread vaccination
Autor:
Mark J. Mulligan, Kizzmekia S. Corbett, Marissa H. Piper, Nicole V. Johnson, Jory A. Goldsmith, Roza Bidshahri, Carl L. Hansen, Robert W. Cross, Daniel Wrapp, A. Pustilnik, Yuri Hwang, Julian Davies, Adil Mohamed, Kathryn Westendorf, Beverly A. Heinz, Olubukola M. Abiona, Lucas Kraft, Jamie L. Blackbourne, Andrew C. Adams, Marie I. Samanovic, Samuel J. Hinshaw, Bryan Edward Jones, Sean A. Tycho, Christopher M. Wiethoff, Shawn J. Berens, Krithika Muthuraman, Stefanie Zentelis, Thomas W. Geisbert, Richard E. Higgs, Ralph S. Baric, Lingshu Wang, Jorg Hendle, Maia A. Smith, Hayley M. Belli, Meike Dittmann, Deepa Balasubramaniam, Solmaz Sobhanifar, Rodrigo Goya, Denisa Foster, John R. Mascola, Viktoriya Borisevich, Thomas P. Cujec, Barney S. Graham, Ping Xiang, Jason S. McLellan, Davide Pellacani, David R. Martinez, Maren de Vries, Patricia Brown-Augsburger, Franz J. Triana, David Collins, Ester Falconer, Kevin R. Jepson, Bryan C. Barnhart, Ching-Lin Hsieh
Publikováno v:
Science Translational Medicine
LY-CoV555, a SARS-CoV-2 spike protein–specific antibody, neutralizes SARS-CoV-2 and protects the airways of nonhuman primates against infection.
A monoclonal for SARS-CoV-2 Among the most promising therapeutic options for individuals with coro
A monoclonal for SARS-CoV-2 Among the most promising therapeutic options for individuals with coro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::910c20bb8473b8eebf9a1ddc2b988951
https://doi.org/10.1101/2020.09.30.318972
https://doi.org/10.1101/2020.09.30.318972
Publikováno v:
Protein Science. 25:787-803
From humble beginnings of a contaminated petri dish, β-lactam antibiotics have distinguished themselves among some of the most powerful drugs in human history. The devastating effects of antibiotic resistance have nevertheless led to an "arms race"
Publikováno v:
Handbook of Antimicrobial Resistance ISBN: 9781493906673
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26837b77d20be2be79c09bde7f8eb6eb
https://doi.org/10.1007/978-1-4939-0694-9_10
https://doi.org/10.1007/978-1-4939-0694-9_10
Autor:
Stephen G. Withers, Solmaz Sobhanifar, Lars Baumann, Eric D. Brown, Robert T. Gale, Gregory A. Wasney, Natalie C. J. Strynadka, Michael Nosella, Liam J. Worrall, Dustin T. King
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 12, Iss 12, p e1006067 (2016)
PLoS Pathogens, Vol 12, Iss 12, p e1006067 (2016)
In recent years, there has been a growing interest in teichoic acids as targets for antibiotic drug design against major clinical pathogens such as Staphylococcus aureus, reflecting the disquieting increase in antibiotic resistance and the historical
Publikováno v:
Current Opinion in Structural Biology. 23:695-703
Growth and maintenance of the protective peptidoglycan cell wall are vital to bacterial growth and morphogenesis. Thus, the relative rate and spatiotemporal control of the synthesis and degradation of this net-like polymer defines bacterial cell shap
Autor:
Krzysztof Mlynarczyk, Frank Löhr, Volker Dötsch, Frank Bernhard, Daniel Gottstein, Peter Güntert, Michal Kolinski, Birgit Schneider, Slawomir Filipek, Wojciech Pulawski, Solmaz Sobhanifar, Teppei Ikeya, Umesh Ghoshdastider
Publikováno v:
Proceedings of the National Academy of Sciences; Vol 107
The γ-secretase complex has a decisive role in the development of Alzheimer’s disease, in that it cleaves a precursor to create the amyloid β peptide whose aggregates form the senile plaques encountered in the brains of patients. Γ-secretase is