Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Soling Zimik"'
Publikováno v:
Frontiers in Physics, Vol 9 (2022)
Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that affect the dynamics of these spiral waves. By using an electrophysiologi
Externí odkaz:
https://doaj.org/article/cade1b4685244fc98e5ac55c8956db3d
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230214 (2020)
Several pathological conditions introduce spatial variations in the electrical properties of cardiac tissue. These variations occur as localized or distributed gradients in ion-channel functionality over extended tissue media. Electrical waves, propa
Externí odkaz:
https://doaj.org/article/673fd24c6ab4498c9c91f33bac837ccb
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144979 (2015)
Premature ventricular complexes (PVCs), which are abnormal impulse propagations in cardiac tissue, can develop because of various reasons including early afterdepolarizations (EADs). We show how a cluster of EAD-generating cells (EAD clump) can lead
Externí odkaz:
https://doaj.org/article/9c55e7ac5e6a4fa9a57fe1c5b6698e3d
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130632 (2015)
Early afterdepolarizations (EADs), which are abnormal oscillations of the membrane potential at the plateau phase of an action potential, are implicated in the development of cardiac arrhythmias like Torsade de Pointes. We carry out extensive numeric
Externí odkaz:
https://doaj.org/article/5db1f517252f45c5bd8b5d16e7bcd676
Autor:
Soling Zimik, Rahul Pandit
Publikováno v:
New Journal of Physics, Vol 18, Iss 12, p 123014 (2016)
Fibroblast–myocyte coupling can modulate electrical-wave dynamics in cardiac tissue. In diseased hearts, the distribution of fibroblasts is heterogeneous, so there can be gradients in the fibroblast density (henceforth we call this GFD) especially
Externí odkaz:
https://doaj.org/article/b9029e1302b943779635ef26b297dc95
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230214 (2020)
PLOS ONE
PLoS ONE
PLOS ONE
PLoS ONE
Several pathological conditions introduce spatial variations in the electrical properties of cardiac tissue. These variations occur as localized or distributed gradients in ion-channel functionality over extended tissue media. Electrical waves, propa
Autor:
Rahul Pandit, Soling Zimik
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Localized heterogeneities, caused by the regional proliferation of fibroblasts, occur in mammalian hearts because of diseases like myocardial infarction. Such fibroblast clumps can become sources of pathological reentrant activities, e.g., spiral or
Spiral-wave Instability in a Medium with a Gradient in the Fibroblast Density: a Computational Study
Autor:
Soling Zimik, Rahul Pandit
Publikováno v:
CinC
Fibrosis, a process of fibroblast proliferation in cardiac tissue, is a major concern for patients with diseases like ischemia, heart failure, and cardiomyopathy, because of its arrhythmogenic effects. Fibroblasts, in appreciable densities, are known
Autor:
Rahul Pandit, Soling Zimik
Publikováno v:
IndraStra Global.
Fibroblast-myocyte coupling can modulate electrical-wave dynamics in cardiac tissue. In diseased hearts, the distribution of fibroblasts is heterogeneous, so there can be gradients in the fibroblast density (henceforth we call this GFD) especially fr
Publikováno v:
PLoS ONE
PLoS ONE, Vol 10, Iss 12, p e0144979 (2015)
PLoS ONE, Vol 10, Iss 12, p e0144979 (2015)
Premature ventricular complexes (PVCs), which are abnormal impulse propagations in cardiac tissue, can develop because of various reasons including early afterdepolarizations (EADs). We show how a cluster of EAD-generating cells (EAD clump) can lead