Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Soline Bourgeois"'
Publikováno v:
Cellular Physiology and Biochemistry, Vol 47, Iss 3, Pp 1095-1107 (2018)
Background/Aims: Homozygous mutations or deletion of the ATP6V1B1 gene encoding for the B1 subunit of the vacuolar H+-ATPase leads to distal renal tubular acidosis in man and mice. In humans, heterozygous carriers of B1 mutations can develop incomple
Externí odkaz:
https://doaj.org/article/af1f4c7d1ed84158ad79c6ea3adc8f5d
Autor:
Arezoo Daryadel, Soline Bourgeois, Marta F L Figueiredo, Ana Gomes Moreira, Nicole B Kampik, Lisa Oberli, Nilufar Mohebbi, Xifeng Lu, Marcel E Meima, A H Jan Danser, Carsten A Wagner
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0147831 (2016)
The (Pro)renin receptor (P)RR/Atp6ap2 is a cell surface protein capable of binding and non-proteolytically activate prorenin. Additionally, (P)RR is associated with H(+)-ATPases and alternative functions in H(+)-ATPase regulation as well as in Wnt si
Externí odkaz:
https://doaj.org/article/e663426370ff461fb5f58d8532cccfb6
Autor:
Thomas Verissimo, Delal Dalga, Grégoire Arnoux, Imene Sakhi, Anna Faivre, Hannah Auwerx, Soline Bourgeois, Deborah Paolucci, Quentin Gex, Joseph M. Rutkowski, David Legouis, Carsten A. Wagner, Andrew M. Hall, Sophie de Seigneux
Phosphoenolpyruvate carboxykinase 1 (PCK1) is highly expressed in the proximal tubule. We show here that this enzyme is crucial for the maintenance of normal tubular physiology, lactate, and glucose homeostasis. PCK1 is a regulator of acid-base balan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c208d60010311a0d49ba4a13417812d2
https://www.zora.uzh.ch/id/eprint/234063/
https://www.zora.uzh.ch/id/eprint/234063/
Autor:
Soline Bourgeois, Jana Kovacikova, Milika Bugarski, Carla Bettoni, Andrew Hall, Carsten Wagner
Publikováno v:
Nephrology Dialysis Transplantation. 37
BACKGROUND AND AIMS Non-type A intercalated cells (IC) in the connecting tubule (CNT) and cortical collecting duct (CCD) express the luminal Cl−/HCO3− exchanger pendrin and apical and/or basolateral vacuolar H+-ATPases containing the B1 subunit i
Autor:
Eva Maria Pastor Arroyo, Nima Yassini, Elif Sakiri, Giancarlo Russo, Soline Bourgeois, Nilufar Mohebbi, Kerstin Amann, Nicole Joller, Carsten A. Wagner, Pedro Henrique Imenez Silva
Chronic kidney disease (CKD) affects approximately 10–13% of the population worldwide and halting its progression is a major clinical challenge. Metabolic acidosis is both a consequence and a possible driver of CKD progression. Alkali therapy count
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368bb7d7ad64b231096c4e2c9a9fc950
Autor:
Arezoo Daryadel, Isabel Rubio-Aliaga, Soline Bourgeois, Marko Ugrica, Nicole Gehring, Eva-Maria Pastor-Arroyo, Nati Hernando, Carla Bettoni, Carsten A. Wagner
Background Phosphate intake has increased in the last decades due to a higher consumption of processed foods. This higher intake is detrimental for patients with chronic kidney disease, increasing mortality and cardiovascular disease risk and acceler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae11f63bc4e6c2f2a99a5f11d2e2b8ce
https://www.zora.uzh.ch/id/eprint/200534/
https://www.zora.uzh.ch/id/eprint/200534/
Autor:
Robert J. Unwin, Joana Raquel Martins, Soline Bourgeois, Dominik Haenni, Susan Ghazi, César Nombela-Arrieta, Carsten A. Wagner, Alvaro Gomariz, Andrew M. Hall, Milica Bugarski, Eilidh Craigie
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 34(6)
Alpha intercalated cells (αICs) in the kidney collecting duct (CD) belong to a family of mitochondria rich cells (MRCs) and have a crucial role in acidifying the urine via apical V-ATPase pumps. The nature of metabolism in αICs and its relationship
NRF2 regulates the glutamine transporter Slc38a3 (SNAT3) in kidney in response to metabolic acidosis
Autor:
Philippe Marbet, Bettina Keller, Isabel Rubio-Aliaga, Carsten A. Wagner, Olivier Devuyst, Alex Odermatt, Hannelore Daniel, Christopher E. Goldring, Pieter Giesbertz, Joanne Walsh, Luke M. Shelton, Ian M. Copple, François Verrey, Pedro Henrique Imenez Silva, Adam Lister, Soline Bourgeois
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Scientific Reports
Expression of the glutamine transporter SNAT3 increases in kidney during metabolic acidosis, suggesting a role during ammoniagenesis. Microarray analysis of Nrf2 knock-out (KO) mouse kidney identified Snat3 as the most significantly down-regulated tr
Autor:
Dennis Brown, Isabelle Mouro-Chanteloup, Carsten A. Wagner, Soline Bourgeois, Yves Colin, Lisa Bounoure
Publikováno v:
Kidney International
Kidney International, Nature Publishing Group, 2018, 93 (2), pp.390-402. ⟨10.1016/j.kint.2017.07.027⟩
Kidney International, Nature Publishing Group, 2018, 93 (2), pp.390-402. ⟨10.1016/j.kint.2017.07.027⟩
Ammonium, stemming from renal ammoniagenesis, is a major urinary proton buffer and is excreted along the collecting duct. This process depends on the concomitant secretion of ammonia by the ammonia channel RhCG and of protons by the vacuolar-type pro
Autor:
Carsten A. Wagner, Mikael Heglind, John A. Sayer, Sumaya Alkanderi, William van’t Hoff, Stephen B. Walsh, Detlef Bockenhauer, Daniel Nilsson, Abdulrahim R.A. Bakhsh, Emma Ashton, Sven Enerbäck, Arezoo Daryadel, Feras E.B. Kokash, Noel Edwards, Robert Kleta, Felice D'Arco, Soline Bourgeois, Asma Deeb
Publikováno v:
Journal of the American Society of Nephrology. 29:1041-1048
Maintenance of the composition of inner ear fluid and regulation of electrolytes and acid-base homeostasis in the collecting duct system of the kidney require an overlapping set of membrane transport proteins regulated by the forkhead transcription f