Zobrazeno 1 - 10
of 1 079
pro vyhledávání: '"Solid tumour"'
Autor:
Jiamin Gao, Weishan Tan, Luyun Yuan, Haoyue Wang, Junkai Wen, Kexiang Sun, Xin Chen, Shuyun Wang, Wanli Deng
Publikováno v:
Heliyon, Vol 10, Iss 5, Pp e27220- (2024)
Tumour-associated macrophages (TAMs), particularly M2-TAMs, constitute the largest proportion of immune cells in the solid tumour microenvironment, playing a crucial role in tumour progression and correlating with poor prognosis. TAMs promote the pro
Externí odkaz:
https://doaj.org/article/8ca8b014fd0947ac8656f394661b9013
Autor:
Wei Wang, Yi Zhang, Yachao Zhang, Nai-Kei Wong, Jun Ma, Jie Li, Long Jin, Lidai Wang, Bai-Ou Guan
Publikováno v:
Materials & Design, Vol 234, Iss , Pp 112304- (2023)
With the recent advances in nanomaterials, photothermal therapies (PTT) enabled by deep-tissue penetration with novel nanoagents have offered a new hope for treating cancers. Nevertheless, PTT applications in conventional approaches remain translatio
Externí odkaz:
https://doaj.org/article/12b08f23e6244ccaac247049dad766ed
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/20d813d1121a4fc899e21e772b2862c8
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1918-1927 (2022)
Histone deacetylases (HDACs) are validated targets for the development of anticancer drugs in epigenetics. In the discovery of novel HDAC inhibitors with anticancer potency, the 5-chloro-4-((substituted phenyl)amino)pyrimidine fragment is assembled a
Externí odkaz:
https://doaj.org/article/10b08077a99545c6bd04fa8660e31c54
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 90-106 (2022)
Glioblastoma multiforme persists to be an enigmatic distress in neuro-oncology. Its untethering capacity to thrive in a confined microenvironment, metastasize intracranially, and remain resistant to the systemic treatments, renders this tumour incura
Externí odkaz:
https://doaj.org/article/e65a8c5fab014cc3bc79885a84cc4265
Akademický článek
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Autor:
John Maher
Publikováno v:
Clinical and Translational Discovery, Vol 3, Iss 2, Pp n/a-n/a (2023)
Abstract Immunotherapy using chimeric antigen receptor (CAR)‐engineered T‐cells has achieved remarkable impact in the treatment of selected blood cancers. However, meaningful clinical efficacy against nonhaematological malignancies has largely pr
Externí odkaz:
https://doaj.org/article/0973d60252a34340b2dc28d98aad4eba
Publikováno v:
IEEE Open Journal of Engineering in Medicine and Biology, Vol 3, Pp 86-95 (2022)
Chimeric antigen receptor (CAR)-T cell therapy is efficacious against many haematological malignancies, but challenges remain when using this cellular immunotherapy for treating solid tumours. Classical 2D in vitro models fail to recapitulate the com
Externí odkaz:
https://doaj.org/article/eaba4ea35d8546e281cfac93783da60e
Autor:
Clara Vigneron, Julien Charpentier, Sandrine Valade, Jérôme Alexandre, Samy Chelabi, Lola-Jade Palmieri, Nathalie Franck, Valérie Laurence, Jean-Paul Mira, Matthieu Jamme, Frédéric Pène
Publikováno v:
Annals of Intensive Care, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Background Major therapeutic advances including immunotherapy and targeted therapies have been changing the face of oncology and resulted in improved prognosis as well as in new toxic complications. The aim of this study is to appraise the t
Externí odkaz:
https://doaj.org/article/a9a7c1acfb784abb83a1fa8b610b77ac
Autor:
Henry Bory Prevez, Argenis Adrian Soutelo Jimenez, Eduardo José Roca Oria, José Alejandro Heredia Kindelán, Maraelys Morales González, Narciso Antonio Villar Goris, Nibaldo Hernández Mesa, Victoriano Gustavo Sierra González, Yenia Infantes Frometa, Juan Ignacio Montijano, Luis Enrique Bergues Cabrales
Publikováno v:
Royal Society Open Science, Vol 9, Iss 11 (2022)
Understanding untreated tumour growth kinetics and its intrinsic behaviour is interesting and intriguing. The aim of this study is to propose an approximate analytical expression that allows us to simulate changes in surface charge density at the can
Externí odkaz:
https://doaj.org/article/27f989f8fe6148e983363c0cf49bd20e