Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Solid phase synthesi"'
Autor:
Alessandra Del Bene, Antonia D'Aniello, Stefano Tomassi, Francesco Merlino, Vincenzo Mazzarella, Rosita Russo, Angela Chambery, Sandro Cosconati, Salvatore Di Maro, Anna Messere
Herein, we developed an innovative and easily accessible solid-phase synthetic protocol for Peptide Nucleic Acid (PNA) oligomers by systematically investigating the ultrasonication effects in all steps of the PNA synthesis (US-PNAS). When compared wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26dffa2f5fccd4ea51b51e145fa5be10
https://hdl.handle.net/11588/915642
https://hdl.handle.net/11588/915642
Autor:
Anna Messere, Salvatore Di Maro, Rosita Russo, Francisco Franco Montalban, Stefano Tomassi, Ettore Novellino
Publikováno v:
Symmetry
Volume 11
Issue 4
Symmetry, Vol 11, Iss 4, p 567 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Volume 11
Issue 4
Symmetry, Vol 11, Iss 4, p 567 (2019)
Digibug. Repositorio Institucional de la Universidad de Granada
instname
Nucleopeptides represent an intriguing class of nucleic acid analogues, in which nucleobases are placed in a peptide structure. The incorporation of D- and/or L-amino acids in nucleopeptide molecules allows the investigation of the role of backbone s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c40e7662ce986ef46f5fa63fa83d7483
http://hdl.handle.net/11588/765865
http://hdl.handle.net/11588/765865
Autor:
Francesco Salvatore, Francesca D'Alessio, Jussara Amato, Francesco Ruffo, Nicola Borbone, Stefano D'Errico, Valentina D'Atri, Giorgia Oliviero, Gennaro Piccialli, Rosa Di Noto, Vincenzo Piccialli
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:5835-5838
Three novel inosine-based dinuclear platinum complexes have been synthesized via a solid-phase strategy. In these compounds, the metal is linked both to the N-7 of the purine nucleus and to the terminal amine group of a hexylamine side chain installe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c07bd3280e1fd82c402eaab9712bbeb3
https://doi.org/10.1016/j.bmcl.2011.07.104
https://doi.org/10.1016/j.bmcl.2011.07.104
Autor:
Jussara Amato, Nicola Borbone, Luciano Mayol, Giorgia Oliviero, Vincenzo Piccialli, Stefano D'Errico, Gennaro Piccialli
Publikováno v:
European Journal of Organic Chemistry. 2010:1517-1524
We report herein a facile, solid-phase synthesis of 5-amino-1-β-D-ribofuranosylimidazole-4-carboxamide-5'-monophosphate (ZMP), a biosynthetic precursor of purine nucleotides,as well as a small collection of its 4-N-alkyl derivatives. Thevery difficu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add849bfdf95c97d7732bc673efc8038
https://doi.org/10.1002/ejoc.200901271
https://doi.org/10.1002/ejoc.200901271
Autor:
Michela Varra, Vincenzo Piccialli, Giorgia Oliviero, Jussara Amato, Luciano Mayol, Nicola Borbone, Gennaro Piccialli, Stefano D'Errico
Publikováno v:
Tetrahedron. 66:1931-1936
We report here an efficient solid-phase synthesis of N -1-alkyl-substituted analogues of cyclic inosine-diphosphate-ribose (cIDPR), a mimic of cyclic ADP-ribose (cADPR). Our synthetic strategy makes use of a polystyrene support to which inosine was b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7366379a4dff9eb4386a85c1eaeb273b
https://doi.org/10.1016/j.tet.2010.01.013
https://doi.org/10.1016/j.tet.2010.01.013
Autor:
Luigi Petraccone, Alfonso Iadonisi, Giovanni Di Fabio, Concetta Giancola, Jan Balzarini, Luigi Martino, Jennifer D'Onofrio, Daniela Montesarchio
Publikováno v:
Bioconjugate Chemistry. 19:607-616
Novel hybrid oligonucleotides carrying the G-quadruplex-forming d(5′TGGGAG3′) sequence, conjugated with mono- or disaccharides at the 3′ or 5′-end through phosphodiester bonds, have been synthesized as potential anti-HIV agents, via a fully a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad625ad359b5521d31c41320418beb0a
https://doi.org/10.1021/bc7003395
https://doi.org/10.1021/bc7003395
Autor:
Lorenzo De Napoli, Giovanni Di Fabio, Daniela Montesarchio, Cinzia Coppola, Jennifer D'Onofrio
Publikováno v:
European Journal of Organic Chemistry. 2007:3849-3858
For potential cation scavenging both from water and from organic solvents, here we propose a synthetic procedure for functionalization of a Tentagel solid support with novel cyclic phosphate-linked oligosaccharide (CyPLOS) analogues. To establish the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c495a341fe6edd59d1f547212d04a65
https://doi.org/10.1002/ejoc.200700203
https://doi.org/10.1002/ejoc.200700203
Autor:
Giorgia Oliviero, Jussara Amato, Gennaro Piccialli, Stefano D'Errico, Nicola Borbone, Luciano Mayol
Publikováno v:
Tetrahedron Letters. 48:397-400
Herein, we report the synthesis and the use of new N-1-dinitrophenyi-inosine based solid supports, in which the C-2 of the purine base is strongly activated toward the attack of N-nucleophiles. The synthesized supports, binding the nucleoside by a 5'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27417829c99019c26714dbb53c960a9f
https://doi.org/10.1016/j.tetlet.2006.11.085
https://doi.org/10.1016/j.tetlet.2006.11.085
Autor:
D'ERRICO, STEFANO, OLIVIERO, GIORGIA, BORBONE, NICOLA, PICCIALLI, VINCENZO, PICCIALLI, GENNARO
This unit contains four basic protocols describing the synthesis of 5-aminoimidazole-4-carboxamide riboside (AICAR), 5-aminoimidazole-4-carboxamide riboside (ZPM), their 4-N functionalized derivatives, and two sugar-modified analogs of AICAR. The fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3730::870f055165ccc1b724fffc62766fea87
http://hdl.handle.net/11588/681257
http://hdl.handle.net/11588/681257
Autor:
Nicoletta Potenza, Armando Zarrelli, Giovanni Di Fabio, Valeria Romanucci, Maria Gaglione, Anna Messere, Jan Balzarini, Sam Noppen, Sandra Liekens
We describe the facile syntheses of new modified oligonucleotides based on d(TG3AG) that form bimolecular G-quadruplexes and possess a HEG loop as an inversion of polarity site 3'-3' or 5'-5' and aromatic residues conjugated to the 5'-end through pho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b649466af341704e3853e47e52aad4
http://hdl.handle.net/11588/651533
http://hdl.handle.net/11588/651533