Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Solenne Marmier"'
Autor:
Pasqualina Colella, Pauline Sellier, Helena Costa Verdera, Francesco Puzzo, Laetitia van Wittenberghe, Nicolas Guerchet, Nathalie Daniele, Bernard Gjata, Solenne Marmier, Severine Charles, Marcelo Simon Sola, Isabella Ragone, Christian Leborgne, Fanny Collaud, Federico Mingozzi
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 12, Iss , Pp 85-101 (2019)
Hepatocyte-restricted, AAV-mediated gene transfer is being used to provide sustained, tolerogenic transgene expression in gene therapy. However, given the episomal status of the AAV genome, this approach cannot be applied to pediatric disorders when
Externí odkaz:
https://doaj.org/article/a3d927f9d1284167b0026e3289c81292
Autor:
Benedicte Noblet, Fadila Benhamed, InSug O-Sullivan, Wenwei Zhang, Gaëlle Filhoulaud, Alexandra Montagner, Arnaud Polizzi, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Tarik Issad, Hervé Guillou, Catherine Bernard, Terry Unterman, Catherine Postic
Publikováno v:
iScience, Vol 24, Iss 3, Pp 102218- (2021)
Summary: TxNIP (Thioredoxin-interacting protein) is considered as a potential drug target for type 2 diabetes. Although TxNIP expression is correlated with hyperglycemia and glucotoxicity in pancreatic β cells, its regulation in liver cells has been
Externí odkaz:
https://doaj.org/article/54c26cec1c3f4bb594dcc0aa898781ca
Autor:
Jules Russick, Pierre-Emmanuel Joubert, Mélanie Gillard-Bocquet, Carine Torset, Maxime Meylan, Florent Petitprez, Marie-Agnes Dragon-Durey, Solenne Marmier, Aditi Varthaman, Nathalie Josseaume, Claire Germain, Pierre Validire, Ludovic Fournel, Audrey Lupo
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background Natural killer (NK) cells play a crucial role in tumor immunosurveillance through their cytotoxic effector functions and their capacity to interact with other immune cells to build a coordinated antitumor immune response. Emerging data rev
Externí odkaz:
https://doaj.org/article/66cfd0aa9b7a4ab3ad675fae3785d405
Autor:
Elena Barbon, Gabriel Ayme, Amel Mohamadi, Jean‐François Ottavi, Charlotte Kawecki, Caterina Casari, Sebastien Verhenne, Solenne Marmier, Laetitia van Wittenberghe, Severine Charles, Fanny Collaud, Cecile V Denis, Olivier D Christophe, Federico Mingozzi, Peter J Lenting
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 4, Pp n/a-n/a (2020)
Abstract Novel therapies for hemophilia, including non‐factor replacement and in vivo gene therapy, are showing promising results in the clinic, including for patients having a history of inhibitor development. Here, we propose a novel therapeutic
Externí odkaz:
https://doaj.org/article/4434607219fc41c0b6465b55049e9dff
Autor:
Amine Meliani, Florence Boisgerault, Romain Hardet, Solenne Marmier, Fanny Collaud, Giuseppe Ronzitti, Christian Leborgne, Helena Costa Verdera, Marcelo Simon Sola, Severine Charles, Alban Vignaud, Laetitia van Wittenberghe, Giorgia Manni, Olivier Christophe, Francesca Fallarino, Christopher Roy, Alicia Michaud, Petr Ilyinskii, Takashi Kei Kishimoto, Federico Mingozzi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Immunogenicity of AAV vectors renders repeated AAV dosing ineffective. Here the authors show that coadministration of nanoparticle-encapsulated rapamycin overcomes AAV immunogenicity through Treg induction, enabling efficient AAV redosing in mice and
Externí odkaz:
https://doaj.org/article/8c201057906f4f2d8d990ffb8e12cbae
Autor:
Amine Meliani, Florence Boisgerault, Zachary Fitzpatrick, Solenne Marmier, Christian Leborgne, Fanny Collaud, Marcelo Simon Sola, Severine Charles, Giuseppe Ronzitti, Alban Vignaud, Laetitia van Wittenberghe, Beatrice Marolleau, Fabienne Jouen, Sisareuth Tan, Olivier Boyer, Olivier Christophe, Alain R. Brisson, Casey A. Maguire, Federico Mingozzi
Publikováno v:
Blood Advances, Vol 1, Iss 23, Pp 2019-2031 (2017)
Abstract: Results from clinical trials of liver gene transfer for hemophilia demonstrate the potential of the adeno-associated virus (AAV) vector platform. However, to achieve therapeutic transgene expression, in some cases high vector doses are requ
Externí odkaz:
https://doaj.org/article/302c51191d2d4ae38857d80e959d437b
Autor:
Alison Iroz, Alexandra Montagner, Fadila Benhamed, Françoise Levavasseur, Arnaud Polizzi, Elodie Anthony, Marion Régnier, Edwin Fouché, Céline Lukowicz, Michèle Cauzac, Emilie Tournier, Marcio Do-Cruzeiro, Martine Daujat-Chavanieu, Sabine Gerbal-Chalouin, Véronique Fauveau, Solenne Marmier, Anne-Françoise Burnol, Sandra Guilmeau, Yannick Lippi, Jean Girard, Walter Wahli, Renaud Dentin, Hervé Guillou, Catherine Postic
Publikováno v:
Cell Reports, Vol 21, Iss 2, Pp 403-416 (2017)
Summary: While the physiological benefits of the fibroblast growth factor 21 (FGF21) hepatokine are documented in response to fasting, little information is available on Fgf21 regulation in a glucose-overload context. We report that peroxisome-prolif
Externí odkaz:
https://doaj.org/article/27cfd3a0fbcd4dd49659cb793fec8873
Autor:
Marion Dajon, Kristina Iribarren, Florent Petitprez, Solenne Marmier, Audrey Lupo, Mélanie Gillard, Hanane Ouakrim, Navas Victor, Di Bartolo Vincenzo, Pierre Emmanuel Joubert, Oliver Kepp, Guido Kroemer, Marco Alifano, Diane Damotte, Isabelle Cremer
Publikováno v:
OncoImmunology, Vol 8, Iss 1 (2019)
In non-small cell lung carcinoma (NSCLC), stimulation of toll-like receptor 7 (TLR7), a receptor for single stranded RNA, is linked to tumor progression and resistance to anticancer chemotherapy. However, the mechanism of this effect has been elusive
Externí odkaz:
https://doaj.org/article/3d8711a3d69047dc912aa59845b4beaa
Autor:
Irati Garmendia, Aditi Varthaman, Solenne Marmier, Mahmud Angrini, Ingrid Matchoua, Aurelie Darbois-Delahousse, Nathalie Josseaume, Pierre-Emmanuel Foy, Lubka T. Roumenina, Naïra Naouar, Maxime Meylan, Sophie Sibéril, Jules Russick, Pierre-Emmanuel Joubert, Karen Leroy, Diane Damotte, Audrey Mansuet-Lupo, Marie Wislez, Marco Alifano, Laurie Menger, Ignacio Garcia-Verdugo, Jean-Michel Sallenave, Olivier Lantz, Florent Petitprez, Isabelle Cremer
Publikováno v:
Cancer Immunology Research. 11:530-545
One billion people worldwide get flu every year, including patients with non–small cell lung cancer (NSCLC). However, the impact of acute influenza A virus (IAV) infection on the composition of the tumor microenvironment (TME) and the clinical outc
Autor:
Isabelle Cremer, Florent Petitprez, Olivier Lantz, Jean-Michel Sallenave, Ignacio Garcia-Verdugo, Laurie Menger, Marco Alifano, Marie Wislez, Audrey Mansuet-Lupo, Diane Damotte, Karen Leroy, Pierre-Emmanuel Joubert, Jules Russick, Sophie Sibéril, Maxime Meylan, Naïra Naouar, Lubka T. Roumenina, Pierre-Emmanuel Foy, Nathalie Josseaume, Aurelie Darbois-Delahousse, Ingrid Matchoua, Mahmud Angrini, Solenne Marmier, Aditi Varthaman, Irati Garmendia
One billion people worldwide get flu every year, including patients with non–small cell lung cancer (NSCLC). However, the impact of acute influenza A virus (IAV) infection on the composition of the tumor microenvironment (TME) and the clinical outc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43874e3d1f3a2b3243ca97e3617be67a
https://doi.org/10.1158/2326-6066.c.6534828
https://doi.org/10.1158/2326-6066.c.6534828