Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Solene Belisle Fabre"'
Autor:
Solene Belisle-Fabre, Augustin Le-Naour, Stéphane Moreau, Pascal Sonnet, Isabelle Forfar, Grace Gosmann, Christian Jarry, François Ravanello, Gérard Déléris, Philippe Grellier, Jean Guillon, Noël Pinaud, Elisabeth Mouray, Vanessa Desplat, Jean-Michel Léger, Catherine Mullié
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2011, 46 (6), pp.2310-2326. ⟨10.1016/j.ejmech.2011.03.014⟩
European Journal of Medicinal Chemistry, Elsevier, 2011, 46 (6), pp.2310-2326
European Journal of Medicinal Chemistry, Elsevier, 2011, 46 (6), pp.2310-2326. ⟨10.1016/j.ejmech.2011.03.014⟩
European Journal of Medicinal Chemistry, Elsevier, 2011, 46 (6), pp.2310-2326
Following our search for antimalarial compounds, novel series of ferrocenyl-substituted pyrrolo[1,2-a]quinoxalines 1-2 were synthesized from ferrocene-carboxaldehyde and tested for their in vitro activity upon the erythrocytic development of Plasmodi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9a91e877b4f535ff43336fb611d1a26
https://hal-mnhn.archives-ouvertes.fr/mnhn-02070071
https://hal-mnhn.archives-ouvertes.fr/mnhn-02070071
Autor:
Djavad Mossalayi, Jean Guillon, Stéphane Massip, Juliette Uranga, Vanessa Desplat, Denis Thiolat, Romain Lucas, Gérard Déléris, Stéphane Moreau, Laure de Moor, Solene Belisle-Fabre, Christian Jarry, Pascal Sonnet
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 26(5)
A novel series of isoindolo[2,1-a]quinoxaline and indolo[1,2-a]quinoxaline derivatives was synthesized and evaluated in vitro against various human cancer cell lines for antiproliferative activity. These new compounds displayed activity against leuke
Autor:
Vanessa Desplat, Stephane Moreau, Aurore Gay, Solene Belisle Fabre, Denis Thiolat, Stephane Massip, Gregory Macky, Frederic Godde, Djavad Mossalayi, Christian Jarry, Jean Guillon
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 25(2)
Attenuation of protein kinases by selective inhibitors is an extremely active field of activity in anticancer drug development. Therefore, Akt, a serine/threonine protein kinase, also known as protein kinase B (PKB), represents an attractive potentia
Autor:
Elisabeth Mouray, Daniel Parzy, Solene Belisle Fabre, Christian Jarry, Jean Guillon, Stéphane Moreau, Véronique Sinou, Vanessa Desplat, Isabelle Forfar, Philippe Grellier, Pascal Millet
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2008, 16 (20), pp.9133-9144. ⟨10.1016/j.bmc.2008.09.038⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2008, 16 (20), pp.9133-9144. ⟨10.1016/j.bmc.2008.09.038⟩
Following our search for antimalarial compounds, novel series of ferrocenic pyrrolo[1,2-a]quinoxaline derivatives 1-2 were synthesized from various substituted nitroanilines and tested for in vitro activity upon the erythrocytic development of Plasmo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd96ccf1b572bd3f0a806e5e2e57996
https://hal-mnhn.archives-ouvertes.fr/mnhn-02070080
https://hal-mnhn.archives-ouvertes.fr/mnhn-02070080
Autor:
Jean Guillon, Stephane Brajot, Stéphane Massip, Djavad Mossalayi, Solene Belisle Fabre, Denis Thiolat, Ambre Geneste, Vanessa Desplat, Marc-Antoine Begorre, Christian Jarry
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 23(5)
Akt kinases are attractive targets for small molecule drug discovery because of their key role in tumor cell survival/proliferation and their overexpression/activation in many human cancers. Recent efforts in the development and biological evaluation
Autor:
Vanessa Desplat, Jean Guillon, Stéphane Massip, Denis Thiolat, Isabelle Forfar, Djavad Mossalayi, Christian Jarry, Solene Belisle Fabre, Hélène Carrié
Publikováno v:
Journal of enzyme inhibition and medicinal chemistry. 22(5)
A series of new 4-(E)-alkenylpyrrolo[1,2-a]quinoxaline derivatives, structural analogues of alkaloid chimanine B, was synthesized in good yields using efficient palladium(0)-catalyzed Suzuki-Miyaura cross-coupling reactions. These new compounds were
Autor:
Vanessa Desplat, Jean Guillon, Stéphane Massip, Djavad Mossalayi, Solene Belisle Fabre, Isabelle Forfar, Christian Jarry
Publikováno v:
Analytical Sciences: X-ray Structure Analysis Online. 24:X35-X36
The X-ray crystal structure of the antileishmanial 7-methoxy-4-[(E)-oct-1-enyl]pyrrolo[1,2-a]quinoxaline was established. It crystallizes in the monoclinic space group P21/c. Solid-state data could be used to clarify the mechanism of action implicati