Sex-specific phenotypical, functional and metabolic profiles of human term placenta macrophages

Autor: Daniel E. Paparini, Esteban Grasso, Franco Aguilera, M. Agustina Arslanian, Victoria Lella, Brenda Lara, Ana Schafir, Soledad Gori, Fátima Merech, Vanesa Hauk, Claudio Schuster, Marcelo Martí, Cesar Meller, Rosanna Ramhorst, Daiana Vota, Claudia Pérez Leirós

Publikováno v: Biology of Sex Differences, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Background Placental macrophages, Hofbauer cells (HBC) are the only fetal immune cell population within the stroma of healthy placenta along pregnancy. They are central players in maintaining immune tolerance during pregnancy. Immunometaboli

Externí odkaz: https://doaj.org/article/87b951a1dc6c453d813d1a0e28471877

VIP Promotes Recruitment of Tregs to the Uterine–Placental Interface During the Peri-Implantation Period to Sustain a Tolerogenic Microenvironment

Autor: Lucila Gallino, Vanesa Hauk, Laura Fernández, Elizabeth Soczewski, Soledad Gori, Esteban Grasso, Guillermina Calo, Nora Saraco, Esperanza Berensztein, James A. Waschek, Claudia Pérez Leirós, Rosanna Ramhorst

Publikováno v: Frontiers in Immunology, Vol 10 (2020)

Uterine receptivity and embryo implantation are two main processes that need a finely regulated balance between pro-inflammatory and tolerogenic mediators to allow a successful pregnancy. The neuroimmune peptide vasoactive intestinal peptide (VIP) is

Externí odkaz: https://doaj.org/article/3724df3d88e04688bd3a950ed0823b54

From decidualization to pregnancy progression: An overview of immune and metabolic effects of VIP

Autor: Rosanna Ramhorst, Esteban Grasso, Daiana Vota, Soledad Gori, Vanesa Hauk, Daniel Paparini, Guillermina Calo, Claudia Pérez Leirós

Publikováno v: American journal of reproductive immunology (New York, N.Y. : 1989)REFERENCES. 88(4)

A tight immune and metabolic regulation underlies the early maternal-placental interaction to assist the energetic dynamic demands of the fetus throughout pregnancy. The vasoactive intestinal peptide (VIP) holds biochemical, metabolic and immune prop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5af0f0365b0c98435521b835b601962b
https://pubmed.ncbi.nlm.nih.gov/35810353

Conditioning of maternal monocytes to myeloid regulatory cells by endometrial stromal cells

Autor: Soledad Gori

Publikováno v: Placenta. 122:2

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d17d218c65ff1250c0c2394d18efda75
https://doi.org/10.1016/j.placenta.2022.03.019

Decidualization Process Induces Maternal Monocytes to Tolerogenic IL-10-Producing Dendritic Cells (DC-10)

Autor: Gabriela Salamone, Fátima Merech, Claudia Perez Leiros, Soledad Gori, Elizabeth Soczewski, Ana Colado, Mercedes Borge, E. Grasso, Lucila Gallino, Rosanna Ramhorst, Laura Fernández

Publikováno v: Frontiers in Immunology, Vol 11 (2020)
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Frontiers in Immunology

Decidualization is a process that involves phenotypic and functional changes of endometrial stromal cells to sustain endometrial receptivity and the participation of immunoregulatory factors to maintain immune homeostasis. In this context, tolerogeni

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2929da79305b7399369ac4a3042715d6
https://www.frontiersin.org/article/10.3389/fimmu.2020.01571/full