Mitochondrial modulation with leriglitazone as a potential treatment for Rett syndrome

Autor: Uliana Musokhranova, Cristina Grau, Cristina Vergara, Laura Rodríguez-Pascau, Clara Xiol, Alba A. Castells, Soledad Alcántara, Pilar Rodríguez-Pombo, Pilar Pizcueta, Marc Martinell, Angels García-Cazorla, Alfonso Oyarzábal

Publikováno v: Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-17 (2023)

Abstract Background Rett syndrome is a neuropediatric disease occurring due to mutations in MECP2 and characterized by a regression in the neuronal development following a normal postnatal growth, which results in the loss of acquired capabilities su

Externí odkaz: https://doaj.org/article/34688ba859f34c5d88309d4927e40819

Neuroprotection with hypothermia and allopurinol in an animal model of hypoxic-ischemic injury: Is it a gender question?

Autor: Javier Rodríguez-Fanjul, Cristina Durán Fernández-Feijóo, Míriam Lopez-Abad, Maria Goretti Lopez Ramos, Rafael Balada Caballé, Soledad Alcántara-Horillo, Marta Camprubí Camprubí

Publikováno v: PLoS ONE, Vol 12, Iss 9, p e0184643 (2017)

Hypoxic-ischemic encephalopathy (HIE) is one of the most important causes of neonatal brain injury. Therapeutic hypothermia (TH) is the standard treatment for term newborns after perinatal hypoxic ischemic injury (HI). Despite this, TH does not provi

Externí odkaz: https://doaj.org/article/460dbfd4edb1462d8d8c1b2aef83acdf

Front Cover

Autor: Ainhoa Pascual‐Alonso, Laura Blasco, Silvia Vidal, Esther Gean, Patricia Rubio, Mar O'Callaghan, Antonio F. Martínez‐Monseny, Alba Aina Castells, Clara Xiol, Vicenç Català, Nuria Brandi, Paola Pacheco, Carlota Ros, Miguel Campo, Encarna Guillén, Salva Ibañez, María J. Sánchez, Pablo Lapunzina, Julián Nevado, Fernando Santos, Elisabet Lloveras, Juan D. Ortigoza‐Escobar, María I. Tejada, Hiart Maortua, Francisco Martínez, Carmen Orellana, Mónica Roselló, María A. Mesas, María Obón, Alberto Plaja, Joaquín A. Fernández‐Ramos, Eduardo Tizzano, Rosario Marín, José L. Peña‐Segura, Soledad Alcántara, Judith Armstrong

Publikováno v: Clinical Genetics. 97

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::202e2ec403763de4affe42e483322c72
https://doi.org/10.1111/cge.13733

Comprehensive Analysis of GABA(A)-A1R Developmental Alterations in Rett Syndrome: Setting the Focus for Therapeutic Targets in the Time Frame of the Disease

Autor: Soledad Alcántara, Mar O'Callaghan, Alfonso Oyarzabal, Mercè Pineda, Angels García-Cazorla, Cristina Grau, Clara Xiol, Alba-Aina Castells, Xavier Altafaj, Judith Armstrong, Guerau Fernandez

Publikováno v: INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
Dipòsit Digital de la UB
Universidad de Barcelona
International Journal of Molecular Sciences, Vol 21, Iss 2, p 518 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 2

Rett syndrome, a serious neurodevelopmental disorder, has been associated with an altered expression of different synaptic-related proteins and aberrant glutamatergic and &gamma
aminobutyric acid (GABA)ergic neurotransmission. Despite its severi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e6923f5c981bfafb66fe2e76ad17740
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=17245

Reply to 'The use of gene expression as disease stratification tool of neonatal encephalopathy'

Autor: Soledad Alcántara, Alfredo García-Alix, Cristian Tebé, Rafael Balada

Publikováno v: Pediatric Research. 89:2-3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1888c21d3cf7aba67b03bad7831cd048
https://doi.org/10.1038/s41390-020-01210-x