Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Solbert Permutt"'
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:693-699
Deep inspiration-induced bronchoprotection and bronchodilation are impaired in asthma. We evaluated the effect of inhaled glucocorticosteroids on these phenomena. Two groups of subjects with asthma, 9 with moderate/severe hyperresponsiveness to metha
Autor:
Roger A. Johns, Solbert Permutt, Hunter C. Champion, J. T. Sylvester, Reda E. Girgis, Gregory B. Diette
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 172:352-357
Decreased nitric oxide (NO) is considered an important pathogenetic mechanism in pulmonary arterial hypertension (PAH), but clear evidence is lacking.We used multiple techniques to assess endogenous NO in 10 patients with untreated PAH (8 idiopathic
Autor:
Robin Yachechko, Mark C. Liu, Solbert Permutt, David Proud, Edward S. Siekierski, Scherer P. Sanders
Publikováno v:
Journal of Allergy and Clinical Immunology. 113:697-702
Background Human rhinovirus (HRV) infections are associated with exacerbations of asthma, chronic obstructive pulmonary disease, and sinusitis. Nitric oxide (NO) might play an important role in host defense through its potent antiviral properties. Pr
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 165:34-40
According to a previously published theoretical model of emphysema, the ratio of RV to TLC (RV/TLC) reflects the size mismatch between the hyperinflated lungs in the disease and the surrounding chest. The model suggests that RV/TLC is an important pr
Autor:
Nicola Scichilone, Robert H. Brown, Solbert Permutt, Fiona B. Diemer, Alkis Togias, Beatrice Mudge
Publikováno v:
Scopus-Elsevier
The effects of a deep inspiration (DI) in individuals with asthma differ from those observed in healthy subjects. It has been postulated that the beneficial effect of lung inflation is mediated by airway stretch. One hypothesis to explain the defects
Publikováno v:
Scopus-Elsevier
In healthy subjects, deep inspiration (DI) acts both as a bronchodilator and a bronchoprotector. The latter is impaired in asthmatics. We have now evaluated whether the lack of bronchoprotection is related to bronchial hyperresponsiveness (BHR), and
Autor:
Christina Anderlind, George Pyrgos, Robert H. Brown, Solbert Permutt, Trigsevgeni Kapsali, Nicola Scichilone, Alkis Togias
Publikováno v:
International Archives of Allergy and Immunology. 124:262-266
Lung inflation has a beneficial effect on the airways of healthy subjects. It acts as a bronchoprotector, that is to prevent bronchoconstriction, and as a bronchodilator, in that it reverses bronchial obstruction. The bronchoprotective effect of deep
Publikováno v:
Scopus-Elsevier
In the absence of deep inspirations, healthy individuals develop bronchoconstriction with methacholine inhalation. One hypothesis is that deep inspiration results in bronchodilation. In this study, we tested an alternative hypothesis, that deep inspi
Autor:
Solbert Permutt, Fiona B. Diemer, Pierre Croisille, Robert H. Brown, Beatrice Mudge, Alkis Togias
Publikováno v:
ResearcherID
Normal subjects prevented from taking a deep breath show changes in airflow similar to those of asthmatics when challenged with methacholine (MCh). To confirm airway narrowing by MCh in this setting and to determine its location, we concurrently meas
Autor:
Solbert Permutt
Publikováno v:
Academic Radiology. 12:1359-1361