Výsledky vyhledávání - "Solari, José Ignácio Gonzalez"

Dissertation/ Thesis

Avaliação da combinação quimioterápica na indução de morte Imunogênica no tratamento de câncer de pulmão de não-pequenas células

Autor: Solari, José Ignácio Gonzalez

Publikováno v: Biblioteca Digital de Teses e Dissertações da UFRGSUniversidade Federal do Rio Grande do SulUFRGS.

O câncer de pulmão é a principal causa de morte por câncer na população mundial. Muitos estudos vêm demonstrando que em determinados tipos tumorais, algumas drogas quimioterápicas estimulam uma eficiente resposta antitumoral, através da indu

Externí odkaz: http://hdl.handle.net/10183/179718

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Akademický článek

Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells.

Autor: Solari, José Ignácio Gonzalez¹ (AUTHOR), Filippi-Chiela, Eduardo^2,3 (AUTHOR) eduardochiela@gmail.com, Pilar, Emily Salles³ (AUTHOR), Nunes, Vitória⁴ (AUTHOR), Gonzalez, Esteban Alberto³ (AUTHOR), Figueiró, Fabrício^4,5 (AUTHOR), Andrade, Cristiano Feijó¹ (AUTHOR), Klamt, Fábio^5,6 (AUTHOR)

Publikováno v: BMC Cancer. 5/26/2020, Vol. 20 Issue 1, p1-14. 14p. 2 Color Photographs, 1 Diagram, 2 Graphs.

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Additional file 7 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 7: Fig. S7 Influence of HMGB1 levels in the prognosis of NSCLC. Kaplan–Meier survival analysis according to HMGB1 levels.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ae37f2c750ea3469701c7b23758bc2b

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Additional file 3 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 3: Fig. S3 Nuclear and LC3 co-staining. Representative images from each treatment are shown. Double arrowheads: nuclei classified as small and regular in the NMA; Arrows – nuclei classified as large in the NMA; Single arrowhead: nuc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::382cfff1f2c1c74ca72868f21148c211

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Additional file 6 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 6: Fig. S6 Correlation matrix to all measurements assessed. ρ coef. Represent the pearson correlation coefficients. Red and green boxes correspond to all negative or positive significant correlations, respectively. Abbreviatures: ‘

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::949e121d4ff9b8fceba67897a75a4747

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Additional file 4 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 4: Fig. S4 Calreticulin (CRT) exposure and its correlation with cell area. (A) Representative histograms of cell count and CRT exposure in the cell surface, as obtained by flow cytometry. *p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b75759705f582fc459a3977c5af513e

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Additional file 5 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 5: Fig. S5 Influence of CRT levels in the prognosis and staging of NSCLC. (A) Kaplan-Meier survival curve to patients expressing high or low levels of CRT in the TCGA cohort. (B) Dead/live ratio of patients for grade i-iv tumors accor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a803baf2c050c90c17091abe3bfc5f97

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Additional file 2 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 2: Fig. S2 Morphological changes and caspase activation in A549 cells treated with chemotherapeutics. (A) Analysis of cell phenotype assessed by flow cytometry. Population 1 indicates normal cell morphology. Reduced cell size (low FSC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53f4a7b394c98dc1915bc2d6f6364e31

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Additional file 1 of Damage-associated molecular patterns (DAMPs) related to immunogenic cell death are differentially triggered by clinically relevant chemotherapeutics in lung adenocarcinoma cells

Autor: Solari, José Ignácio Gonzalez, Filippi-Chiela, Eduardo, Pilar, Emily Salles, Nunes, Vitória, Gonzalez, Esteban Alberto, Fabrício Figueiró, Andrade, Cristiano Feijó, Fábio Klamt

Additional file 1: Fig. S1 Dose-response curves in A549 cells. Cells were treated with the chemotherapeutics as indicated, for 48 h. After this, cell number was determined through flow cytometry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248971ff3e776563396de7500096905a

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