Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Solange M.S.V. Wardell"'
Autor:
Rosana H.C.N. Freitas, Juliana M.C. Barbosa, Patrícia Bernardino, Vitor Sueth-Santiago, Solange M.S.V. Wardell, James L. Wardell, Débora Decoté-Ricardo, Tatiana G. Melo, Edson F. da Silva, Kelly Salomão, Carlos A.M. Fraga
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss , Pp 110162- (2020)
Herein, we present the design, synthesis and trypanocidal evaluation of sixteen new 1,3,4-thiadiazole derivatives from N-aminobenzyl or N-arylhydrazone series. All derivatives were assayed against the trypomastigote form of Trypanosoma cruzi, showing
Externí odkaz:
https://doaj.org/article/2913247f852a4bbe8cac3322fa6ea291
Autor:
Carlos A.M. Fraga, Giulianna P. de Alcântara, Juliana M.C. Barbosa, Kelly Salomão, Solange L. de Castro, James L. Wardell, John N. Low, Solange M.S.V. Wardell, Samir A. Carvalho, Edson F. da Silva
Publikováno v:
Letters in Drug Design & Discovery. 20:488-497
Background: The drugs available for the treatment of Chagas disease are ineffective in its chronic phase and produce many adverse effects, making the search for new drugs an urgent medical need. Objective: This study aimed to design, synthesize, and