Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Solange Landreville"'
Autor:
Kelly Coutant, Brice Magne, Karel Ferland, Aurélie Fuentes-Rodriguez, Olivier Chancy, Andrew Mitchell, Lucie Germain, Solange Landreville
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-18 (2024)
Abstract Melanocytes are dendritic cells localized in skin, eyes, hair follicles, ears, heart and central nervous system. They are characterized by the presence of melanosomes enriched in melanin which are responsible for skin, eye and hair pigmentat
Externí odkaz:
https://doaj.org/article/65ef924c40504b6d8a03573e85098657
Publikováno v:
Cells, Vol 13, Iss 12, p 1023 (2024)
Uveal melanoma (UM), a distinct subtype of melanoma, presents unique challenges in its clinical management due to its complex molecular landscape and tendency for liver metastasis. This review highlights recent advancements in understanding the molec
Externí odkaz:
https://doaj.org/article/8bad78abdc8c4dc8ab3bfa9cd669f5a5
LKB1‐SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition
Autor:
Sarah Proteau, Imène Krossa, Chrystel Husser, Maxime Guéguinou, Federica Sella, Karine Bille, Marie Irondelle, Mélanie Dalmasso, Thibault Barouillet, Yann Cheli, Céline Pisibon, Nicole Arrighi, Sacha Nahon‐Estève, Arnaud Martel, Lauris Gastaud, Sandra Lassalle, Olivier Mignen, Patrick Brest, Nathalie M Mazure, Frédéric Bost, Stéphanie Baillif, Solange Landreville, Simon Turcotte, Dan Hasson, Saul Carcamo, Christophe Vandier, Emily Bernstein, Laurent Yvan‐Charvet, Mitchell P Levesque, Robert Ballotti, Corine Bertolotto, Thomas Strub
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp n/a-n/a (2023)
Abstract Metastatic uveal melanomas are highly resistant to all existing treatments. To address this critical issue, we performed a kinome‐wide CRISPR‐Cas9 knockout screen, which revealed the LKB1‐SIK2 module in restraining uveal melanoma tumor
Externí odkaz:
https://doaj.org/article/1a3e75bad0684eebb8afbad93d505cd9
Autor:
Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna L. Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, J. William Harbour, Zachary T. Schug, Andrew E. Aplin
Publikováno v:
Cancers, Vol 15, Iss 13, p 3451 (2023)
Uveal melanoma (UM) displays a high frequency of metastasis; however, effective therapies for metastatic UM are limited. Identifying unique metabolic features of UM may provide a potential targeting strategy. A lipid metabolism protein expression sig
Externí odkaz:
https://doaj.org/article/bd1520908be04ad1b023ec228e9a8999
Autor:
Léo Piquet, Kelly Coutant, Andrew Mitchell, Amel Ben Anes, Enola Bollmann, Nathan Schoonjans, Julie Bérubé, François Bordeleau, Alain Brisson, Solange Landreville
Publikováno v:
Cells, Vol 11, Iss 23, p 3828 (2022)
Uveal melanoma (UM) is the most common primary intraocular tumor and often spreads to the liver. Intercellular communication though extracellular vesicles (EVs) plays an important role in several oncogenic processes, including metastasis, therapeutic
Externí odkaz:
https://doaj.org/article/795134d1bb4c44d1972efb4ba8125c56
Autor:
Léo Piquet, Louise Dewit, Nathan Schoonjans, Martial Millet, Julie Bérubé, Peter R. A. Gerges, François Bordeleau, Solange Landreville
Publikováno v:
Cancers, Vol 11, Iss 8, p 1043 (2019)
Uveal melanoma (UM) is a malignant intraocular tumor that spreads to the liver in half of the cases. Since hepatic cells could play a role in the therapeutic resistance of metastatic UM, the purpose of our study was to investigate the pro-invasive ro
Externí odkaz:
https://doaj.org/article/0be60e650ec14bc097d4bbd6b4d793c0
Autor:
Aplin, Anna Han, Dzmitry Mukha, Vivian Chua, Timothy J. Purwin, Manoela Tiago, Bhavik Modasia, Usman Baqai, Jenna L. Aumiller, Nelisa Bechtel, Emily Hunter, Meggie Danielson, Mizue Terai, Philip B. Wedegaertner, Takami Sato, Solange Landreville, Michael A. Davies, Stefan Kurtenbach, J. William Harbour, Zachary T. Schug, Andrew E.
Publikováno v:
Cancers; Volume 15; Issue 13; Pages: 3451
Uveal melanoma (UM) displays a high frequency of metastasis; however, effective therapies for metastatic UM are limited. Identifying unique metabolic features of UM may provide a potential targeting strategy. A lipid metabolism protein expression sig
Autor:
J. William Harbour, Anne M. Bowcock, Ryan S. Lee, Michael D. Onken, Zachary T. Kneass, Katie A. Matatall, Olga A. Agapova, Solange Landreville
PDf file - 8.7MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142b4b2fba8c7df0361d6391eab5ae4f
https://doi.org/10.1158/1078-0432.22444322
https://doi.org/10.1158/1078-0432.22444322
Autor:
J. William Harbour, Anne M. Bowcock, Ryan S. Lee, Michael D. Onken, Zachary T. Kneass, Katie A. Matatall, Olga A. Agapova, Solange Landreville
Purpose: Metastasis is responsible for the death of most cancer patients, yet few therapeutic agents are available which specifically target the molecular events that lead to metastasis. We recently showed that inactivating mutations in the tumor sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a8c0f2721e8105d93117095d5f527c
https://doi.org/10.1158/1078-0432.c.6520130
https://doi.org/10.1158/1078-0432.c.6520130
Autor:
J. William Harbour, Anne M. Bowcock, Ryan S. Lee, Michael D. Onken, Zachary T. Kneass, Katie A. Matatall, Olga A. Agapova, Solange Landreville
PDF file - 1.9MB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2c0ec8493eb150f7abf576ec610010
https://doi.org/10.1158/1078-0432.22444310.v1
https://doi.org/10.1158/1078-0432.22444310.v1