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Autor:
Jean Benhattar, Lucienne Juillerat-Jeanneret, Solange Gros, Robert C. Janzer, Sylviane Trepey, Charlotte Bricod, Catherine Chapuis Bernasconi
Publikováno v:
Cancer investigation. 26(6)
The DNA repair and detoxifying enzymes, O(6)-methylguanine-DNA-methyltransferase (MGMT) and glutathione-S-transferase (GST), may be responsible fpr poor response to alkylating agents in glioblastoma treatment. The methylation of MGMT promoter and the