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Hijacking of the O-GlcNAcZYME complex by the HTLV-1 Tax oncoprotein facilitates viral transcription.
Autor:
Damien Groussaud, Mostafa Khair, Armelle I Tollenaere, Laetitia Waast, Mei-Shiue Kuo, Marianne Mangeney, Christophe Martella, Yann Fardini, Solène Coste, Mouloud Souidi, Laurence Benit, Claudine Pique, Tarik Issad
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006518 (2017)
The viral Tax oncoprotein plays a key role in both Human T-cell lymphotropic virus type 1 (HTLV-1)-replication and HTLV-1-associated pathologies, notably adult T-cell leukemia. Tax governs the transcription from the viral 5'LTR, enhancing thereby its
Externí odkaz:
https://doaj.org/article/c404bc8567a54b58ada8727ec1829b1c