Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Sokolowska-Wedzina A"'
Autor:
Marta Pozniak, Aleksandra Sokolowska‐Wedzina, Kamil Jastrzebski, Jakub Szymczyk, Natalia Porebska, Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Marta Miaczynska, Jacek Otlewski, Lukasz Opalinski
Publikováno v:
Molecular Oncology, Vol 14, Iss 9, Pp 1998-2021 (2020)
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitu
Externí odkaz:
https://doaj.org/article/41add822f32c4099b544103cf1062b2c
Autor:
Mateusz Adam Krzyscik, Malgorzata Zakrzewska, Vigdis Sørensen, Aleksandra Sokolowska-Wedzina, Michal Lobocki, Karolina Weronika Swiderska, Daniel Krowarsch, Antoni Wiedlocha, Jacek Otlewski
Publikováno v:
ACS Omega, Vol 2, Iss 7, Pp 3792-3805 (2017)
Externí odkaz:
https://doaj.org/article/187efb47319e4e688b8c5315fd2347c4
Autor:
Jacek Otlewski, Malgorzata Zakrzewska, Aleksandra Borek, Julia Chudzian, Grzegorz Chodaczek, Aleksandra Sokolowska-Wedzina
Supplementary Materials and Methods - Description of affinity maturation procedure used in the study and of the preparation of scFvD2 diabody and scFvD2-Fc; Supplementary Figure S1 - Reactivity of scFv clones against Fc fragment; Supplementary Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a5886c73fdc612ef08d289909f7e515
https://doi.org/10.1158/1541-7786.22511946.v1
https://doi.org/10.1158/1541-7786.22511946.v1
Autor:
Jacek Otlewski, Malgorzata Zakrzewska, Aleksandra Borek, Julia Chudzian, Grzegorz Chodaczek, Aleksandra Sokolowska-Wedzina
Targeted delivery of anticancer drugs using antibodies specific for tumor-associated antigens represents one of the most important approaches in current immuno-oncology research. Fibroblast growth factor receptor 1 (FGFR1) has been demonstrated to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7fcc6f46d3dbe75b0bea3ff3f3e51b6
https://doi.org/10.1158/1541-7786.c.6540084.v1
https://doi.org/10.1158/1541-7786.c.6540084.v1
Autor:
Sokolowska-Wedzina, Aleksandra, Borek, Aleksandra, Chudzian, Julia, Jakimowicz, Piotr, Zakrzewska, Malgorzata, Otlewski, Jacek
Publikováno v:
In Protein Expression and Purification July 2014 99:50-57
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192194 (2018)
Fibroblast growth factor receptors (FGFRs) are promising targets for antibody-based cancer therapies, as their substantial overexpression has been found in various tumor cells. Aberrant activation of FGF receptor 2 (FGFR2) signaling through overexpre
Externí odkaz:
https://doaj.org/article/d73d37e30b2446d88396c627277803c3
Autor:
Mateusz Adam Krzyścik, Marta Poźniak, Łukasz Opaliński, Natalia Porębska, Martyna Sochacka, Jakub Szymczyk, Kamil Jastrzębski, Aleksandra Sokolowska-Wedzina, Malgorzata Zakrzewska, Jacek Otlewski
Publikováno v:
Molecular Medicine
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Molecular Medicine, Vol 27, Iss 1, Pp 1-13 (2021)
Background Antibody drug conjugates (ADCs) represent one of the most promising approaches in the current immuno-oncology research. The precise delivery of cytotoxic drugs to the cancer cells using ADCs specific for tumor-associated antigens enables s
Autor:
Borek, Aleksandra1, Sokolowska-Wedzina, Aleksandra1, Chodaczek, Grzegorz2, Otlewski, Jacek1 jacek.otlewski@uwr.edu.pl
Publikováno v:
PLoS ONE. 2/8/2018, Vol. 13 Issue 2, p1-16. 16p.
Autor:
Daria Nawrocka, Aleksandra Sokolowska-Wedzina, Karolina Jendryczko, Mateusz Adam Krzyscik, Natalia Porębska, Marta Pozniak, Malgorzata Zakrzewska, Lukasz Opalinski, Jacek Otlewski, Anna Szlachcic
Publikováno v:
Journal of Visualized Experiments.
Cancer is currently the second most common cause of death worldwide. The hallmark of cancer cells is the presence of specific marker proteins such as growth factor receptors on their surface. This feature enables development of highly selective thera
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