Sweet Battle of the Epimers─Continued Exploration of Monosaccharide-Derived Delivery Agents for Boron Neutron Capture Therapy.

Autor: Matović J; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, Helsinki FI-00014, Finland., Bahrami K; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, Kuopio FI-70211, Finland., Stockmann P; Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Leipzig University, Leipzig D-04103, Germany., Sokka IK; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, Helsinki FI-00014, Finland., Khng YC; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, Helsinki FI-00014, Finland., Sarparanta M; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, Helsinki FI-00014, Finland., Hey-Hawkins E; Faculty of Chemistry and Mineralogy, Institute of Inorganic Chemistry, Leipzig University, Leipzig D-04103, Germany., Rautio J; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, Kuopio FI-70211, Finland., Ekholm FS; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, Helsinki FI-00014, Finland.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2023 Jun 05; Vol. 20 (6), pp. 3127-3139. Date of Electronic Publication: 2023 May 03.

Halogenation at the Phenylalanine Residue of Monomethyl Auristatin F Leads to a Favorable cis / trans Equilibrium and Retained Cytotoxicity.

Autor: Sokka IK; Department of Chemistry, University of Helsinki, P.O. Box 55, A. I. Virtasen aukio 1, FI-00014 Helsinki, Finland., Imlimthan S; Department of Chemistry, University of Helsinki, P.O. Box 55, A. I. Virtasen aukio 1, FI-00014 Helsinki, Finland., Sarparanta M; Department of Chemistry, University of Helsinki, P.O. Box 55, A. I. Virtasen aukio 1, FI-00014 Helsinki, Finland., Maaheimo H; VTT Technical Research Centre of Finland Ltd, P.O. Box 1000, VTT, FI-02044 Espoo, Finland., Johansson MP; Department of Chemistry, University of Helsinki, P.O. Box 55, A. I. Virtasen aukio 1, FI-00014 Helsinki, Finland.; CSC, IT Center for Science Ltd., P.O. Box 405, FI-02101 Espoo, Finland., Ekholm FS; Department of Chemistry, University of Helsinki, P.O. Box 55, A. I. Virtasen aukio 1, FI-00014 Helsinki, Finland.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2021 Aug 02; Vol. 18 (8), pp. 3125-3131. Date of Electronic Publication: 2021 Jul 23.

Addressing the Biochemical Foundations of a Glucose-Based "Trojan Horse"-Strategy to Boron Neutron Capture Therapy: From Chemical Synthesis to In Vitro Assessment.

Autor: Matović J; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Järvinen J; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland., Bland HC; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Sokka IK; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Imlimthan S; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Ferrando RM; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Huttunen KM; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland., Timonen J; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland., Peräniemi S; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland., Aitio O; Glykos Finland Ltd., Viikinkaari 6, FI-00790 Helsinki, Finland., Airaksinen AJ; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland.; Turku PET Centre, Department of Chemistry, University of Turku, P.O. Box 52, FI-20521 Turku, Finland., Sarparanta M; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland., Johansson MP; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland.; Helsinki Institute of Sustainability Science, HELSUS, FI-00014 Helsinki, Finland., Rautio J; School of Pharmacy, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland., Ekholm FS; Department of Chemistry, University of Helsinki, Finland, P.O. Box 55, FI-00014 Helsinki, Finland.

Publikováno v: Molecular pharmaceutics [Mol Pharm] 2020 Oct 05; Vol. 17 (10), pp. 3885-3899. Date of Electronic Publication: 2020 Sep 02.