Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Sok Kuan Wong"'
Publikováno v:
Heliyon, Vol 10, Iss 13, Pp e34064- (2024)
Background and objective: Osteoarthritis (OA) is the most common age-related disease of joints with increasing global prevalence. Persistent inflammation within the joint space is speculated to be the cause of OA. Resveratrol is an anti-inflammatory
Externí odkaz:
https://doaj.org/article/baeb38329ad04282b5affbd3c2bea8a4
Autor:
Nyruz Ramadan Elahmer, Sok Kuan Wong, Norazlina Mohamed, Ekram Alias, Kok-Yong Chin, Norliza Muhammad
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1635 (2024)
Osteoporosis, a metabolic bone disorder characterized by decreased bone mass per unit volume, poses a significant global health burden due to its association with heightened fracture risk and adverse impacts on patients’ quality of life. This revie
Externí odkaz:
https://doaj.org/article/a325786608c94647961442ecceb659f5
Autor:
Sophia Ogechi Ekeuku, Muhamed Lahtif Nor Muhamad, Alya Aqilah Aminuddin, Fairus Ahmad, Sok Kuan Wong, Wun Fui Mark-Lee, Kok-Yong Chin
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 170, Iss , Pp 115998- (2024)
Postmenopausal women are susceptible to osteoporosis and osteoarthritis. Tocotrienol, a bone-protective nutraceutical, is reported to prevent osteoarthritis in male rats. However, its efficacy on joint health in oestrogen deficiency has not been vali
Externí odkaz:
https://doaj.org/article/82f52e6edb094ce0ac53166e4748324e
Autor:
Sok Kuan Wong
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 502 (2024)
Glycogen synthase kinase 3-beta (GSK3β) is a highly conserved protein kinase originally involved in glucose metabolism, insulin activity, and energy homeostasis. Recent scientific evidence demonstrated the significant role of GSK3β in regulating bo
Externí odkaz:
https://doaj.org/article/e55da118f159434ca843a6a1744f2a37
Autor:
Aswini Kumareswaran, Sophia Ogechi Ekeuku, Norazlina Mohamed, Norliza Muhammad, Alfizah Hanafiah, Kok-Lun Pang, Sok Kuan Wong, Deborah Chia Hsin Chew, Kok-Yong Chin
Publikováno v:
Life, Vol 13, Iss 9, p 1882 (2023)
Gut dysbiosis has been associated with many chronic diseases, such as obesity, inflammatory bowel disease, and cancer. Gut dysbiosis triggers these diseases through the activation of the immune system by the endotoxins produced by gut microbiota, whi
Externí odkaz:
https://doaj.org/article/9bf8827824a644f3863e5eb70029a76e
Autor:
Sok Kuan Wong, Nur Irdina Adlin Fikri, Karthikgeyan Munesveran, Nur Syaqeerah Nor Hisham, Shirley Hui Jin Lau, Kok-Yong Chin, Nur Azlina Mohd Fahami, Qodriyah Hj Mohd Saad, Yusof Kamisah, Azman Abdullah, Norliana Masbah, Soelaiman Ima-Nirwana
Publikováno v:
Journal of Functional Foods, Vol 96, Iss , Pp 105213- (2022)
The potential of osteocyte-mediated phosphate homeostasis as a molecular link between metabolic syndrome and osteoporosis remains to be elucidated. This study investigated the osteocyte lacunar network, levels of osteocyte-specific molecules and phos
Externí odkaz:
https://doaj.org/article/afa042fa05694565b2c56b3437c46ebc
Autor:
Sophia Ogechi Ekeuku, Kok-Yong Chin, Jing Qian, Yan Zhang, Haibin Qu, Elvy Suhana Mohd Ramli, Sok Kuan Wong, Mohd Mustazil Mohd Noor, Soelaiman Ima-Nirwana
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 152, Iss , Pp 113265- (2022)
The current prevention options for postmenopausal osteoporosis are very limited. E’Jiao is a collagen-rich traditional Chinese medicine with the potential to prevent osteoporosis but more comprehensive investigations are lacking. This study aimed t
Externí odkaz:
https://doaj.org/article/137e46db01cf4bf1b3034406b151e312
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 5, p 286 (2023)
The management of bone defects is complicated by the presence of clinical conditions, such as critical-sized defects created by high-energy trauma, tumour resection, infection, and skeletal abnormalities, whereby the bone regeneration capacity is com
Externí odkaz:
https://doaj.org/article/d7b580f68c044731a0fd1a6ad7df5ace
Publikováno v:
Biomedicines, Vol 10, Iss 12, p 3239 (2022)
Metabolic syndrome (MetS) refers to a cluster of metabolic dysregulations, which include insulin resistance, obesity, atherogenic dyslipidemia and hypertension. The complex pathogenesis of MetS encompasses the interplay between environmental and gene
Externí odkaz:
https://doaj.org/article/6e74b03d33b241e48a3474fbd2878ecb
Autor:
Ban-Hock Khor, Hui-Ci Tiong, Shing Cheng Tan, Sok Kuan Wong, Kok-Yong Chin, Tilakavati Karupaiah, Soelaiman Ima-Nirwana, Abdul Halim Abdul Gafor
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0255205 (2021)
Studies investigating the effects of tocotrienols on inflammation and oxidative stress have yielded inconsistent results. This systematic review and meta-analysis aimed to evaluate the effects of tocotrienols supplementation on inflammatory and oxida
Externí odkaz:
https://doaj.org/article/056cf97347764b178456e38f4b30d76b