Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Soizick Mesnage"'
Autor:
Michael T. Richardson, Catherine Genestie, Sebastien Gouy, Amandine Maulard, Soizick Mesnage, Philippe Morice, Elisa Yaniz Galende, Patricia Pautier, Alexandra Leary, Audrey Le Formal, Chloé Brizais, F. Blanc-Durand
Publikováno v:
Gynecologic Oncology. 160:279-284
Background The disappointing activity of single agent immune-checkpoint inhibitors in epitherlial ovarian cancer (EOC) has been attributed in part to its unique tumor microenvironment (TME). IDO, PDL1, LAG3 and TIM3 have been implicated in the immuno
Autor:
Françoise Drusch, Judith Michels, Philippe Morice, Aya S. Khairallah, Amandine Maulard, Sebastien Gouy, Enrica Bentivegna, Bianca Cheaib, Audrey LeFormal, Catherine Genestie, Soizick Mesnage, Patricia Pautier, Ariane Dunant, Alexandra Leary, F. Blanc-Durand
Publikováno v:
Cancer Immunology, Immunotherapy
Background At diagnosis, tumor-infiltrating lymphocytes (TILs) are prognostic in epithelial ovarian cancer (EOC). We recently demonstrated that neoadjuvant chemotherapy (NACT) significantly increased stromal TILs. Here, we investigated the impact of
Autor:
Colin R Lindsay, Pier Francesco Ferrucci, Giuseppe Tonini, Dara Stein, Victoria Atkinson, Paola Queirolo, Barbara Merelli, Philippe Legenne, Massimo Aglietta, Klaus Freivogel, Soizick Mesnage, Michele Del Vecchio, Helen Linardou, Bart Neyns, Salvador Martín-Algarra, Lindi Dalland, Vanna Chiarion-Sileni, Michael Millward, Jonathan Cebon, Rebecca A. Hinshelwood, Mike Lau
Publikováno v:
Melanoma Research. 29:527-532
Given the approval of dabrafenib in patients with BRAF-mutant metastatic melanoma, a better understanding of treatment patterns and clinical outcomes with dabrafenib in a clinical setting is warranted. We performed a retrospective chart review of pat
Autor:
Michael Findlay, Soizick Mesnage, Kathryn Payne, Cherie Blenkiron, Cris Print, Rosalie Stephens, PS Houseman, Paula Shields, Tamsin Robb, Kathryn F. Chrystal, H Hameed, Michelle Wilson
Publikováno v:
Poster.
Introduction In clear cell ovarian cancers (CCOC) limited data is available on genomic evolution with disease progression. Methods 23 FFPE tumours collected from 12 patients with advanced CCOC, and 1 mixed clear cell endometrioid OC, treated at Auckl
Publikováno v:
Current Opinion in Oncology. 28:404-411
Purpose of review The proven activity of poly ADP ribose polymerase (PARP) inhibitors in BRCA-mutated homologous recombination deficient (HRD) ovarian cancer has led to the availability to patients with ovarian cancer of the first targeted therapy wi
Autor:
P. Morice, Françoise Drusch, A. Le Formal, E. Bentivegna, Alexandra Leary, Aurélie Auguste, Patricia Pautier, Soizick Mesnage, Catherine Genestie, Erwann Pain, Judith Michels, Bianca Cheaib, Julien Adam, Sebastien Gouy, Catherine Lhommé, Ariane Dunant
Publikováno v:
Annals of oncology : official journal of the European Society for Medical Oncology. 28(3)
Lymphocytic infiltration at diagnosis is prognostic in EOC, however, the impact of NACT on tumour infiltrating lymphocytes (TILs) or PD-L1 expression remains poorly described.Patients with EOC and sequential samples (pre-NACT, post-NACT or relapse) w
Autor:
Sebastien Gouy, P. Morice, E. Bentivegna, Marc Deloger, Catherine Genestie, Patricia Pautier, Soizick Mesnage, Bastien Job, Yannick Boursin, Alexandra Leary, Julien Adam, Judith Michels, A. Leformal-Ensarguex, Aurélie Auguste
Publikováno v:
Annals of Oncology. 28:v337-v338
Autor:
Peter C.C. Fong, Soizick Mesnage, Wilfred Levin, Helen Mackay, Lisa Wang, Kathryn Payne, Kathryn F. Chrystal, Amit M. Oza, Stephane Laframboise, Michelle K. Wilson, Marjan Rouzbahman, Andrew N. Shelling
Publikováno v:
Gynecologic oncology. 138(2)
Optimal management of women with early stage granulosa cell tumours (GCT) presents a management conundrum — they have excellent prognosis but a third will relapse. Advances uncovering the molecular characteristics of GCT have not been matched by im
Autor:
Soizick Mesnage, Enrica Bentivegna, Elena Cojocaru, Sebastien Gouy, Aurélie Auguste, Catherine Genestie, Audrey Le Formal, Alexandra Leary, Julien Adam, Catherine Lhommé, Patricia Pautier, Françoise Drusch
Publikováno v:
Molecular Cancer Research. 15:B02-B02
Background: HGOC is frequently diagnosed at an advanced stage where NeoAdjuvant Chemotherapy (NACT) provides an essential component of the treatment strategy. HGOC are initially very chemosensitive, putatively due to DNA repair defects. While BRCA mu
Autor:
Catherine Lhommé, Catherine Genestie, Erwann Pain, Philippe Morice, Patricia Pautier, Aurélie Auguste, Bianca Cheaib, Judith Michels, Ariane Dunant, Françoise Drusch, Soizick Mesnage, Enrica Bentivegna, Sebastien Gouy, Audrey Le Formal, Alexandra Leary, Julien Adam
Publikováno v:
Journal of Clinical Oncology. 35:64-64
64 Background: Tumour immune response plays a critical role in progression and prognosis of EOC, however patterns of TILs and PD-L1 expression in primary and metastatic disease remain poorly described. Methods: Patients treated with neoadjuvant chemo