Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Soili I Lehtonen"'
Autor:
Nitin Agrawal, Soili I Lehtonen, Meri Uusi-Mäkelä, Purvi Jain, Sari Viitala, Juha A E Määttä, Niklas Kähkönen, Latifeh Azizi, Tiina A Riihimäki, Markku S Kulomaa, Mark S Johnson, Vesa P Hytönen, Tomi T Airenne
Publikováno v:
PLoS ONE, Vol 14, Iss 2, p e0212339 (2019)
Chicken avidin (Avd) and streptavidin from Streptomyces avidinii are extensively used in bionanotechnology due to their extremely tight binding to biotin (Kd ~ 10-15 M for chicken Avd). We previously reported engineered Avds known as antidins, which
Externí odkaz:
https://doaj.org/article/addaf38daa174d15b4a834c6349f099d
Autor:
Markku S. Kulomaa, Sampo Kukkurainen, Tiina A. Riihimäki, Nitin Agrawal, Masi Koskinen, Mark S. Johnson, Antti Tullila, Niklas Kähkönen, Tomi T. Airenne, Tarja K. Nevanen, Soili I. Lehtonen, Vesa P. Hytönen
Publikováno v:
Lehtonen, S I, Tullila, A, Agrawal, N, Kukkurainen, S, Kähkönen, N, Koskinen, M, Nevanen, T K, Johnson, M S, Airenne, T T, Kulomaa, M S, Riihimäki, T A & Hytönen, V P 2016, ' Artificial avidin-based receptors for a panel of small molecules ', ACS Chemical Biology, vol. 11, no. 1, pp. 211-221 . https://doi.org/10.1021/acschembio.5b00906
Proteins with high specificity, affinity, and stability are needed for biomolecular recognition in a plethora of applications. Antibodies are powerful affinity tools, but they may also suffer from limitations such as low stability and high production
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6a031479973723878b09d21e72ca27c
https://cris.vtt.fi/en/publications/79e78d3d-a693-4568-8141-75eb28c1b107
https://cris.vtt.fi/en/publications/79e78d3d-a693-4568-8141-75eb28c1b107
Autor:
Yang Deng, Ludovic Bannwarth, Titus J. Boggon, Heung-Chin Cheng, Benjamin E. Turk, Nilda L. Alicea-Velázquez, Soili I. Lehtonen, Vesa P. Hytönen
Publikováno v:
Journal of Proteome Research
Protein kinases phosphorylate substrates in the context of specific phosphorylation site sequence motifs. The knowledge of the specific sequences that are recognized by kinases is useful for mapping sites of phosphorylation in protein substrates and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c76fb915c953500d75dfdc2f7b161c88
https://doi.org/10.1021/pr500503q
https://doi.org/10.1021/pr500503q
Autor:
Vesa P. Hytönen, Martina Rangl, Soili I. Lehtonen, Hermann J. Gruber, Tiina A. Riihimäki, Markku S. Kulomaa, Andreas Ebner, Michael Leitner, Peter Hinterdorfer
Publikováno v:
Journal of Molecular Recognition. 27:92-97
Molecular recognition force spectroscopy, a biosensing atomic force microscopy technique allows to characterise the dissociation of ligand-receptor complexes at the molecular level. Here, we used molecular recognition force spectroscopy to study the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cd61695a394f2a294a702f0f7adb600
https://doi.org/10.1002/jmr.2337
https://doi.org/10.1002/jmr.2337
Autor:
Sari Viitala, Tomi T. Airenne, Soili I. Lehtonen, Niklas Kähkönen, Meri I. E. Uusi-Mäkelä, Juha A. E. Määttä, Markku S. Kulomaa, Purvi Jain, Tiina A. Riihimäki, Latifeh Azizi, Vesa P. Hytönen, Nitin Agrawal, Mark S. Johnson
Publikováno v:
'PloS One ', vol: 14, pages: e0212339-1-e0212339-27 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212339 (2019)
PLoS ONE
PLoS ONE, Vol 14, Iss 2, p e0212339 (2019)
Chicken avidin (Avd) and streptavidin from Streptomyces avidinii are extensively used in bionanotechnology due to their extremely tight binding to biotin (K-d similar to 10(-15) M for chicken Avd). We previously reported engineered Avds known as anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fc5363e479486187867f75a7b8f4de3
https://doi.org/10.1371/journal.pone.0212339
https://doi.org/10.1371/journal.pone.0212339
Autor:
Juha A. E. Määttä, Vesa P. Hytönen, Niklas Kähkönen, Markku S. Kulomaa, Soili I. Lehtonen, Hermann J. Gruber, Teemu O. Ihalainen, Masi Koskinen, Chloe Thomson, Sampo Kukkurainen, Dominik Zauner, Barbara Taskinen
Publikováno v:
Bioconjugate chemistry. 25(12)
Switchavidin is a chicken avidin mutant displaying reversible binding to biotin, an improved binding affinity toward conjugated biotin, and low nonspecific binding due to reduced surface charge. These properties make switchavidin an optimal tool in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112b7318de1e6166e1a964c927ac730c
https://pubmed.ncbi.nlm.nih.gov/25405260
https://pubmed.ncbi.nlm.nih.gov/25405260