Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Soichiro Kakuta"'
Autor:
Tetsuya Kotani, Yuji Sakai, Hiromi Kirisako, Chika Kakuta, Soichiro Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract In autophagy, a membrane cisterna called the isolation membrane expands, bends, becomes spherical, and closes to sequester cytoplasmic constituents into the resulting double-membrane vesicle autophagosome for lysosomal/vacuolar degradation.
Externí odkaz:
https://doaj.org/article/6fb6d83a63724c03a4afa4a07ad6e9e1
Autor:
Sayaka Shizukuishi, Michinaga Ogawa, Eisuke Kuroda, Shigeto Hamaguchi, Chisato Sakuma, Soichiro Kakuta, Isei Tanida, Yasuo Uchiyama, Yukihiro Akeda, Akihide Ryo, Makoto Ohnishi
Publikováno v:
Cell Reports, Vol 43, Iss 3, Pp 113962- (2024)
Summary: Pneumolysin (Ply) is an indispensable cholesterol-dependent cytolysin for pneumococcal infection. Although Ply-induced disruption of pneumococci-containing endosomal vesicles is a prerequisite for the evasion of endolysosomal bacterial clear
Externí odkaz:
https://doaj.org/article/d6adba8baf80479c868bdf88e7e8ecf2
Publikováno v:
Autophagy Reports, Vol 2, Iss 1 (2023)
ATG9A is an important membrane protein in mammalian macroautophagy. The formation of autophagosomes and phagophores is blocked in atg9a KO cells. However, it remains possible that residual membrane formation activity exists in these cells. These prec
Externí odkaz:
https://doaj.org/article/6e574d7da9f64470a356e2e4c3d30b16
Autor:
Takeshi Kameyama, Muneaki Miyata, Hajime Shiotani, Jun Adachi, Soichiro Kakuta, Yasuo Uchiyama, Kiyohito Mizutani, Yoshimi Takai
Publikováno v:
iScience, Vol 26, Iss 10, Pp 108010- (2023)
Summary: Astrocytes interact with not only synapses but also brain blood vessels through perivascular astrocyte endfeet (PV-AEF) to form the neurovascular unit (NVU). However, PV-AEF components have not been fully identified. Here, we biochemically i
Externí odkaz:
https://doaj.org/article/284f87b094cb43ccba6d8301bf19a4f1
Autor:
Mutsumi Yokota, Yutaro Yoshino, Mitsuko Hosoi, Ryota Hashimoto, Soichiro Kakuta, Takahiro Shiga, Kei-Ichi Ishikawa, Hideyuki Okano, Nobutaka Hattori, Wado Akamatsu, Masato Koike
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Endoplasmic reticulum-mitochondrial contact sites (ERMCS) play an important role in mitochondrial dynamics, calcium signaling, and autophagy. Disruption of the ERMCS has been linked to several neurodegenerative diseases, including Alzheimer’s disea
Externí odkaz:
https://doaj.org/article/4aa9abf1f0a54d21b9a3929c6aafe40d
Publikováno v:
Heliyon, Vol 9, Iss 6, Pp e17394- (2023)
In-resin CLEM (Correlative Light and Electron Microscopy) of Epon-embedded cells involves correlating fluorescence microscopy with electron microscopy in the same Epon-embedded ultrathin section. This method offers the advantage of high positional ac
Externí odkaz:
https://doaj.org/article/381002c4a6c342d4bcb9dd7a75c5f43e
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Biotin ligases have been developed as proximity biotinylation enzymes for analyses of the interactome. However, there has been no report on the application of proximity labeling for in-resin correlative light-electron microscopy of Epon-embe
Externí odkaz:
https://doaj.org/article/612a87f889c0423e99c63a7b64245df5
Autor:
Takayuki Miyaki, Nozomi Homma, Yuto Kawasaki, Mami Kishi, Junji Yamaguchi, Soichiro Kakuta, Tomoko Shindo, Makoto Sugiura, Oliva Trejo, Juan Alejandro, Hisako Kaneda, Takuya Omotehara, Masaki Takechi, Takako Negishi-Koga, Muneaki Ishijima, Kazushi Aoto, Sachiko Iseki, Kosuke Kitamura, Satoru Muto, Mao Amagasa, Shiori Hotchi
Publikováno v:
Journal of Cell Science; Oct2024, Vol. 137 Issue 20, p1-15, 15p
Autor:
Mutsumi Yokota, Soichiro Kakuta, Takahiro Shiga, Kei-ichi Ishikawa, Hideyuki Okano, Nobutaka Hattori, Wado Akamatsu, Masato Koike
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-18 (2021)
Abstract Mitochondrial structural changes are associated with the regulation of mitochondrial function, apoptosis, and neurodegenerative diseases. PRKN is known to be involved with various mechanisms of mitochondrial quality control including mitocho
Externí odkaz:
https://doaj.org/article/0b00ee531f2040729435d60ecf707a02
Autor:
Isei Tanida, Yoko Furuta, Junji Yamaguchi, Soichiro Kakuta, Juan Alejandro Oliva Trejo, Yasuo Uchiyama
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract In-resin CLEM of Epon embedded samples can greatly simplify the correlation of fluorescent images with electron micrographs. The usefulness of this technique is limited at present by the low number of fluorescent proteins that resist CLEM pr
Externí odkaz:
https://doaj.org/article/84e16da512444879bfc9d6a0294bd7cd