Zobrazeno 1 - 10
of 276
pro vyhledávání: '"Soichi, Wakatsuki"'
Crystal structure of the 4-hydroxybutyryl-CoA synthetase (ADP-forming) from nitrosopumilus maritimus
Autor:
Jerome Johnson, Bradley B. Tolar, Bilge Tosun, Yasuo Yoshikuni, Christopher A. Francis, Soichi Wakatsuki, Hasan DeMirci
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract The 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle from ammonia-oxidizing Thaumarchaeota is currently considered the most energy-efficient aerobic carbon fixation pathway. The Nitrosopumilus maritimus 4-hydroxybutyryl-CoA synthetase (
Externí odkaz:
https://doaj.org/article/b0074faf961d4e1784f937a5b876db42
Autor:
Tetsumori Yamashima, Daria Mochly-Rosen, Soichi Wakatsuki, Eishiro Mizukoshi, Takuya Seike, Isabel Maria Larus, Che-Hong Chen, Miho Takemura, Hisashi Saito, Akihiro Ohashi
Publikováno v:
Frontiers in Molecular Biosciences, Vol 11 (2024)
Autophagy mediates the degradation of intracellular macromolecules and organelles within lysosomes. There are three types of autophagy: macroautophagy, microautophagy, and chaperone-mediated autophagy. Heat shock protein 70.1 (Hsp70.1) exhibits dual
Externí odkaz:
https://doaj.org/article/eee398e828314d8f9bda7fabb7eb97e6
Autor:
Michael J Currie, James S Davies, Mariafrancesca Scalise, Ashutosh Gulati, Joshua D Wright, Michael C Newton-Vesty, Gayan S Abeysekera, Ramaswamy Subramanian, Weixiao Y Wahlgren, Rosmarie Friemann, Jane R Allison, Peter D Mace, Michael DW Griffin, Borries Demeler, Soichi Wakatsuki, David Drew, Cesare Indiveri, Renwick CJ Dobson, Rachel A North
Publikováno v:
eLife, Vol 12 (2024)
Tripartite ATP-independent periplasmic (TRAP) transporters are secondary-active transporters that receive their substrates via a soluble-binding protein to move bioorganic acids across bacterial or archaeal cell membranes. Recent cryo-electron micros
Externí odkaz:
https://doaj.org/article/59de71f8bf864a14be2120a060302bca
Autor:
Brian C. Sanders, Suman Pokhrel, Audrey D. Labbe, Irimpan I. Mathews, Connor J. Cooper, Russell B. Davidson, Gwyndalyn Phillips, Kevin L. Weiss, Qiu Zhang, Hugh O’Neill, Manat Kaur, Jurgen G. Schmidt, Walter Reichard, Surekha Surendranathan, Jyothi Parvathareddy, Lexi Phillips, Christopher Rainville, David E. Sterner, Desigan Kumaran, Babak Andi, Gyorgy Babnigg, Nigel W. Moriarty, Paul D. Adams, Andrzej Joachimiak, Brett L. Hurst, Suresh Kumar, Tauseef R. Butt, Colleen B. Jonsson, Lori Ferrins, Soichi Wakatsuki, Stephanie Galanie, Martha S. Head, Jerry M. Parks
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
The development of direct-acting antivirals to combat COVID-19 remains an important goal. Here the authors design covalent inhibitors that target the papain-like protease from SARS-CoV-2. The most promising inhibitor blocks viral replication in mamma
Externí odkaz:
https://doaj.org/article/fd261a622e08487782f550c5d0f5bc31
Autor:
James S. Davies, Michael J. Currie, Rachel A. North, Mariafrancesca Scalise, Joshua D. Wright, Jack M. Copping, Daniela M. Remus, Ashutosh Gulati, Dustin R. Morado, Sam A. Jamieson, Michael C. Newton-Vesty, Gayan S. Abeysekera, Subramanian Ramaswamy, Rosmarie Friemann, Soichi Wakatsuki, Jane R. Allison, Cesare Indiveri, David Drew, Peter D. Mace, Renwick C. J. Dobson
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Bacteria and archaea use tripartite ATP-independent periplasmic (TRAP) transporters to import essential nutrients. Davies et al. report a high resolution structure of a TRAP and show that it uses an ‘elevator-with-an operator’ mechanism.
Externí odkaz:
https://doaj.org/article/a1b3692949d14006b916bdaba4de7228
Autor:
Nai-Chi Chen, Chun-Hsiung Wang, Masato Yoshimura, Yi-Qi Yeh, Hong-Hsiang Guan, Phimonphan Chuankhayan, Chien-Chih Lin, Pei-Ju Lin, Yen-Chieh Huang, Soichi Wakatsuki, Meng-Chiao Ho, Chun-Jung Chen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Viruses can cause Colony Collapse Disorder, leading to large losses of honeybee hives globally. In this study, the authors solve capsid structures of honeybee-infecting Lake Sinai viruses and identify distinct features, which advances understanding o
Externí odkaz:
https://doaj.org/article/f21c98a297944033a2fab46ed62b6422
Autor:
Mikhail A. Hameedi, Erica T. Prates, Michael R. Garvin, Irimpan I. Mathews, B. Kirtley Amos, Omar Demerdash, Mark Bechthold, Mamta Iyer, Simin Rahighi, Daniel W. Kneller, Andrey Kovalevsky, Stephan Irle, Van-Quan Vuong, Julie C. Mitchell, Audrey Labbe, Stephanie Galanie, Soichi Wakatsuki, Daniel Jacobson
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The authors report crystallographic and computational studies that detail how SARS-CoV-2 3CLpro cleaves the host NF-κB Essential Modulator in addition to its canonical viral substrates. The association with the high fitness of SARS-CoV-2 in humans i
Externí odkaz:
https://doaj.org/article/f4a60ed5420947fea700b6dd36aeb82f
Autor:
Kaiming Zhang, Naoki Horikoshi, Shanshan Li, Alexander S. Powers, Mikhail A. Hameedi, Grigore D. Pintilie, Hee-Don Chae, Yousuf A. Khan, Carl-Mikael Suomivuori, Ron O. Dror, Kathleen M. Sakamoto, Wah Chiu, Soichi Wakatsuki
Publikováno v:
ACS Central Science, Vol 8, Iss 2, Pp 214-222 (2022)
Externí odkaz:
https://doaj.org/article/65bfa553069248ed93809a76bca79c14
Autor:
Ebru Destan, Busra Yuksel, Bradley B. Tolar, Esra Ayan, Sam Deutsch, Yasuo Yoshikuni, Soichi Wakatsuki, Christopher A. Francis, Hasan DeMirci
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract The ammonia-oxidizing thaumarchaeal 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle is one of the most energy-efficient CO2 fixation cycles discovered thus far. The protein encoded by Nmar_1308 (from Nitrosopumilus maritimus SCM1) is a
Externí odkaz:
https://doaj.org/article/9facd89c002a40c5b7cd6090b588717b
Autor:
Colin J. Comerci, Jonathan Herrmann, Joshua Yoon, Fatemeh Jabbarpour, Xiaofeng Zhou, John F. Nomellini, John Smit, Lucy Shapiro, Soichi Wakatsuki, W. E. Moerner
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Bacteria assemble the surface layer (S-layer), a crystalline protein coat surrounding the curved surface, using protein self-assembly. Here authors image native and purified RsaA, the S-layer protein from C. crescentus, and show that protein crystall
Externí odkaz:
https://doaj.org/article/dff21d49c92d4800b6501520ddadea62