Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Soi Cheng Law"'
Autor:
Mika Casey, Carol Lee, Sharon M. Hoyte, Rebecca L. Johnston, Wing Yu Kwok, Soi Cheng Law, Maher K Gandhi, Simon J Harrison, Kyohei Nakamura
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
T-cell-engaging bispecific antibody (T-BsAb, also known as BiTE) therapy has emerged as a powerful therapeutic modality against multiple myeloma. Given that T-BsAb therapy redirects endogenous T cells to eliminate tumor cells, reinvigorating dysfunct
Externí odkaz:
https://doaj.org/article/e2b3c87782cc4f26af9c0283b3578f4b
Autor:
Mika Casey, Carol Lee, Wing Yu Kwok, Soi Cheng Law, Dillon Corvino, Maher K Gandhi, Simon J Harrison, Kyohei Nakamura
Publikováno v:
Haematologica, Vol 109, Iss 3 (2023)
T-cell-engaging bispecific antibodies (T-BsAb) have produced impressive clinical responses in patients with relapsed/refractory B-cell malignancies, although treatment failure remains a major clinical challenge. Growing evidence suggests that a compl
Externí odkaz:
https://doaj.org/article/b870098d16af4da8a6a9bc4158d2a216
Autor:
Mohamed Shanavas, Soi‐Cheng Law, Mark Hertzberg, Rodney J Hicks, John F Seymour, Zhixiu Li, Lilia Merida de Long, Karthik Nath, Muhammed B Sabdia, Jay Gunawardana, Maher K Gandhi, Colm Keane
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Abstract Objectives A diverse intratumoral T‐cell receptor (TCR) repertoire is associated with improved survival in diffuse large B‐cell lymphoma (DLBCL) treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R‐CHOP) chem
Externí odkaz:
https://doaj.org/article/50bba13efe444391a61f0d8ffaa50fb2
Autor:
Mika Casey, Kane Segawa, Soi Cheng Law, Muhamamed Bilal Sabdia, Bianca Nowlan, Basit Salik, Carol Lee, Clay Winterford, Sally Pearson, Jason Madore, William C. Dougall, Maher K. Gandhi, Kyohei Nakamura
Publikováno v:
Leukemia.
Redirection of tumor-associated macrophages to eliminate tumor cells holds great promise for overcoming therapeutic resistance to rituximab and other antibody drugs. Here, we determined the expression of ectonucleotidases CD39 and CD73 in diffuse lar
Autor:
Gayathri Thillaiyampalam, Sally Mujaj, Cameron Snell, Frank Vari, Maher K. Gandhi, Madeline Gough, Jamie P. Nourse, Colm Keane, Soi Cheng Law, Muhammed B. Sabdia, Rachael A. West, Alexandre S. Cristino, Jay Gunawardana
Publikováno v:
Blood. 134:2261-2270
Epstein-Barr virus–positive (EBV(+)) diffuse large B-cell lymphomas (DLBCLs) express high levels of programmed death ligand 1 (PD-L1) and PD-L2. MicroRNA (miR) regulation is an important mechanism for the fine-tuning of gene expression via 3′-unt
Autor:
Jay Gunawardana, Soi Cheng Law, Sabdia, Muhammed B., Karolina Bednarska, Sandra Brosda, Zaharia, Andreea, Hennes Tsang, Lilia Merida de Long, Burgess, Melinda, Talaulikar, Dipti, Lee, Justina N., Jude, Emily, Hawkes, Eliza A., Jain, Sanjiv, Nath, Karthik, Gould, Clare, Swain, Fiona, Joshua Tobin, colm keane, Birch, Simone, Mohamed Shanavas, Snell, Cameron, Maher Gandhi
Publikováno v:
University of Queensland
Hodgkin lymphoma (HL) comprises two distinct disease entities based on clinical, morphologic and genotypic characteristics. Relative to classical Hodgkin Lymphoma (cHL), nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is rare, and its tumor m
Autor:
Mohamed Shanavas, Judith Trotman, Maher K. Gandhi, Phillip Law, Karthik Nath, Donna Cross, Muhammed B. Sabdia, Sarah-Jane Halliday, Lilia M. de Long, Hennes Tsang, Soi Cheng Law, Robert Bird, David P. Sester, Joshua W.D. Tobin, Jay Gunawardana, Colm Keane, Sanjiv Jain, Annette Hernandez, Dipti Talaulikar
Publikováno v:
Blood Adv
Data on the prognostic impact of pretherapy 18F-fluorodeoxyglucose–positron emission tomography (FDG-PET) in follicular lymphoma (FL) is conflicting. The predictive utility of pretherapy total metabolic tumor volume (TMTV) and maximum standardized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847d81833d6ca43fdb61430471d25b97
https://europepmc.org/articles/PMC8270658/
https://europepmc.org/articles/PMC8270658/
Autor:
Lilia Merida de Long, Mark Hertzberg, Karthik Nath, Jay Gunawardana, John F. Seymour, Zhixiu Li, Mohamed Shanavas, Colm Keane, Maher K. Gandhi, Rodney J. Hicks, Muhammed B. Sabdia, Soi Cheng Law
Publikováno v:
Clinical & Translational Immunology
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Clinical & Translational Immunology, Vol 10, Iss 11, Pp n/a-n/a (2021)
Objectives A diverse intratumoral T‐cell receptor (TCR) repertoire is associated with improved survival in diffuse large B‐cell lymphoma (DLBCL) treated with rituximab/cyclophosphamide/doxorubicin/prednisolone/vincristine (R‐CHOP) chemoimmunoth
Autor:
Valentine Murigneux, J. Lynn Fink, Colm Keane, Oliver Weigert, Santiyagu M. Savarimuthu Francis, Frank Vari, Simone Birch, Maher K. Gandhi, Christian Steidl, Robert Kridel, Thanh Hoang, Wolfram Klapper, Li Huang, Nicholas Matigian, Li Li, Michelle N. Wykes, Laurie H. Sehn, Peter Mollee, Joshua W.D. Tobin, Sarah Haebe, Soi Cheng Law, Jay Gunawardana, Justina Lee, Vindi Jurinovic
Publikováno v:
Journal of Clinical Oncology
PURPOSE Understanding the immunobiology of the 15% to 30% of patients with follicular lymphoma (FL) who experience progression of disease within 24 months (POD24) remains a priority. Solid tumors with low levels of intratumoral immune infiltration ha
Autor:
Shuvashis Dey, Jennifer R Tyler, Jing Wang, Hendrik J. Nel, Jamie Rossjohn, Matt Trau, Abu Ali Ibn Sina, Soi Cheng Law, Ramanathan Vaidyanathan, Yuling Wang, K. Kamil Reza, Hugh H. Reid, Ranjeny Thomas
Publikováno v:
Sensors and Actuators B: Chemical. 284:281-288
T-cells play a major role in host defense mechanisms against many diseases. With the current growth of immunotherapy approaches, there is a strong need for advanced technologies to detect and characterize these immune cells. Herein, we present a simp