Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Sohyun Hwang"'
Publikováno v:
PLoS ONE, Vol 19, Iss 3, p e0298128 (2024)
ObjectivePoly(ADP-ribose) polymerase (PARP) inhibitors are used for targeted therapy for ovarian cancer with homologous recombination deficiency (HRD). In this study, we aimed to develop a homologous recombination deficiency prediction model to predi
Externí odkaz:
https://doaj.org/article/d6f09af313494684b9f9a13f51d50772
Autor:
Joo Dong Park, Hye Jung Jang, Seung Hee Choi, Gae Hoon Jo, Jin-Ho Choi, Sohyun Hwang, Wooram Park, Kyung-Soon Park
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-10 (2023)
Abstract Triple-negative breast cancer (TNBC) is the most lethal form of breast cancer. TNBC patients have higher rates of metastasis and restricted therapy options. Although chemotherapy is the conventional treatment for TNBC, the frequent occurrenc
Externí odkaz:
https://doaj.org/article/e40c390627d249dd8298a38547c67576
Autor:
Sohyun Hwang, Jaejoon Lim, Haeyoun Kang, Ju-Yeon Jeong, Je-Gun Joung, Jinhyung Heo, Daun Jung, Kyunggi Cho, Hee Jung An
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background Recurrent glioblastoma multiforme (GBM) is a highly aggressive primary malignant brain tumor that is resistant to existing treatments. Recently, we reported that activated autologous natural killer (NK) cell therapeutics induced a
Externí odkaz:
https://doaj.org/article/9bcc41a2725b4215ae1f35aee73aa482
Publikováno v:
Fertility & Reproduction, Vol 05, Iss 04, Pp 701-701 (2023)
Background and Aims: Current literature suggests that blastocyst ET (Embryo Transfer) at day 5 improves pregnancy outcomes compared with cleavage ET at day 3. However, blastocyst ET poses potential challenges due to the risk of developmental arrest a
Externí odkaz:
https://doaj.org/article/825523c54a2f4ab88de1e774190ef7ed
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114700- (2023)
Ubiquitin-specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUBs) that remove mono or polyubiquitin chains from target proteins. Depending on cancer types, USP7 has two opposing roles: oncogene or tumor suppressor. Moreover, it also
Externí odkaz:
https://doaj.org/article/70c8728df397446c803a4840360f0ae2
Publikováno v:
Cell Death and Disease, Vol 13, Iss 8, Pp 1-13 (2022)
Abstract Ubiquitin-specific protease 7 (USP7) is one of the deubiquitinating enzymes (DUBs) in the ubiquitin-specific protease (USP) family. It is a key regulator of numerous cellular functions including immune response, cell cycle, DNA damage and re
Externí odkaz:
https://doaj.org/article/d7dba26a6a5444e6a34dd64f23e141bd
Autor:
Daun Jung, Young Seok Baek, In Jee Lee, Ki Yeon Kim, Heejoo Jang, Sohyun Hwang, Jieun Jung, Yong-wha Moon, Kyung-Soon Park, Yong-Soo Choi, Hee Jung An
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-14 (2021)
Abstract Background Recently, allogeneic natural killer (NK) cells have gained considerable attention as promising immunotherapeutic tools due to their unique biological functions and characteristics. Although many NK expansion strategies have been r
Externí odkaz:
https://doaj.org/article/0012dff126bd4b0a93bde27377c06b52
Autor:
So Young Kim, Seungmin Lee, Go Hun Seo, Bong Jik Kim, Doo Yi Oh, Jin Hee Han, Moo Kyun Park, So min Lee, Bonggi Kim, Nayoung Yi, Namju Justin Kim, Doo Hyun Koh, Sohyun Hwang, Changwon Keum, Byung Yoon Choi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Variant prioritization of exome sequencing (ES) data for molecular diagnosis of sensorineural hearing loss (SNHL) with extreme etiologic heterogeneity poses a significant challenge. This study used an automated variant prioritization system
Externí odkaz:
https://doaj.org/article/debc16281735427387c11105f50bd90f
Autor:
Jin-Ho Choi, Joo Dong Park, Kwang-Soo Kim, Seung Hee Choi, Gae Hoon Jo, Si-Won Park, Eun-Su Ko, Minwook Lee, Dae-Keum Lee, Hye Jung Jang, Sohyun Hwang, Hae-Yun Jung, Kyung-Soon Park
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 7 (2022)
Background Triple negative breast cancer (TNBC) is the most lethal subtype of breast cancer due to its aggressive behavior and frequent development of resistance to chemotherapy. Although natural killer (NK) cell-based immunotherapy is a promising st
Externí odkaz:
https://doaj.org/article/2f63601538e64f49aa85bf46af486164
Publikováno v:
Genes, Vol 14, Iss 4, p 886 (2023)
In ovarian cancer patients, the 5-year survival rate is 90% for stages I and II, but only 30% for stages III and IV. Unfortunately, as 75% of the patients are diagnosed at stages III and IV, many experience a recurrence. To ameliorate this, it is nec
Externí odkaz:
https://doaj.org/article/fa39dce270674e3b9ae4ea33ad82e55e